Zobrazeno 1 - 10
of 690
pro vyhledávání: '"R, Gurny"'
Autor:
Moritz Radbruch, Jörg Raabe, Annika Vogt, Lars Mundhenk, Sebastian Bachmann, Achim D. Gruber, Fiorenza Rancan, Eckart Rühl, R. Gurny, Benjamin Watts, A. Klossek, Hannah Pischon, K. Yamamoto, R. Flesch, Petra Schrade, Ulrike Blume-Peytavi, K. Fuchs
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 139:68-75
The penetration of topically applied tacrolimus formulated in micelles into murine skin is reported, measured by X-ray microscopy. Tacrolimus and micelles are probed for the first time by this high spatial resolution technique by element-selective ex
Autor:
J, Heller, J, Barr, S Y, Ng, H R, Shen, K, Schwach-Abdellaoui, S, Einmahl, A, Rothen-Weinhold, R, Gurny, S, Emmahl
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 50, No 1 (2000) pp. 121-128
Poly(ortho esters) have been under development since the early 1970s and four families of such polymers have been described. Of most interest are poly(ortho ester) III and poly(ortho ester) IV. Poly(ortho ester) III is a semisolid material that has b
Publikováno v:
Photochemistry and photobiology. 77(6)
The cellular uptake, localization and efflux of meso-tetra-(4-hydroxyphenyl)porphyrin (p-THPP)-loaded nanoparticles have been studied in EMT-6 tumor cells. The effect of blood serum on photocytotoxicity has also been evaluated. Sub-130 nm nanoparticl
Publikováno v:
Pharmaceutical research. 18(8)
To investigate the potential use of polymeric nanoparticles for the delivery of antisense oligonucleotides in HIV-1-infected cell cultures.Phosphorothioate oligonucleotides were encapsulated into poly (D,L-lactic acid) nanoparticles. Two models of in
Autor:
I, Brigger, P, Chaminade, D, Desmaële, M T, Peracchia, J, d'Angelo, R, Gurny, M, Renoir, P, Couvreur
Publikováno v:
Pharmaceutical research. 17(9)
To progress in the characterization of a poly(MePEGcyanoacrylate-co-hexadecylcyanoacrylate) (poly(PEGCA-co-HDCA) copolymer and the nanoparticles formed from this copolymer.Poly(PEGCA-co-HDCA) at a MePEG/hexadecyl ratio of 1:4 was investigated by 1H-N
Autor:
R Gurny
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 50(1)
Autor:
S, Einmahl, F, Behar-Cohen, C, Tabatabay, M, Savoldelli, F, D'Hermies, D, Chauvaud, J, Heller, R, Gurny
Publikováno v:
Journal of biomedical materials research. 50(4)
The biocompatibility of a viscous, hydrophobic, bioerodible poly(ortho ester) (POE) intended for intraocular application was investigated. POE was evaluated as a blank carrier and as containing modulators of degradation. Each formulation was injected
Publikováno v:
Pharmaceutical research. 16(6)
To investigate the feasibility of producing freeze-dried poly(ethylene oxide) (PEO)-surface modified nanoparticles and to study their ability to avoid the mononuclear phagocytic system (MPS), as a function of the PEO chain length and surface density.
Publikováno v:
Critical reviews in therapeutic drug carrier systems. 15(4)
Development of ophthalmic drug-delivery systems has always been challenging. The commonly used route for drug delivery to the anterior segment of the eye has been the conjunctival cul-de-sac. Because of drawbacks associated with this route, new appro