Zobrazeno 1 - 10
of 204
pro vyhledávání: '"R, Gundle"'
Autor:
Kenneth R. Gundle, Karthik Rajasekaran, Jeffrey Houlton, Gary B. Deutsch, Thomas J. Ow, Robert G. Maki, John Pang, Cherie-Ann O. Nathan, Daniel Clayburgh, Jason G. Newman, Elyse Brinkmann, Michael J. Wagner, Seth M. Pollack, Matthew J. Thompson, Ryan J. Li, Vikas Mehta, Bradley A. Schiff, Barry I. Wenig, Paul L. Swiecicki, Alice L. Tang, Jessica L. Davis, Annemieke van Zante, Jessica A. Bertout, Wendy Jenkins, Atticus Turner, Marc Grenley, Connor Burns, Jason P. Frazier, Angela Merrell, Kimberly H. W. Sottero, Jonathan M. J. Derry, Kate C. Gillespie, Bre Mills, Richard A. Klinghoffer
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Drug development is systemically inefficient. Research and development costs for novel therapeutics average hundreds of millions to billions of dollars, with the overall likelihood of approval estimated to be as low as 6.7% for oncology
Externí odkaz:
https://doaj.org/article/df356ddd88154387999a5c867f337370
Autor:
Ryland Kagan, Lindsay Parlee, Brooke Beckett, James B Hayden, Kenneth R Gundle, Yee-Cheen Doung
Publikováno v:
Acta Orthopaedica, Vol 91, Iss 2, Pp 171-176 (2020)
Background and purpose — Compressive osseointegration fixation is an alternative to intramedullary fixation for endoprosthetic reconstruction. Mechanical failure of compressive osseointegration presents differently on radiographs than stemmed impla
Externí odkaz:
https://doaj.org/article/9e18adef0ab149868850296c98db8082
Publikováno v:
Orthopedic Reviews, Vol 12, Iss 3 (2020)
This review summarizes the biomechanical concepts, clinical outcomes and limitations of compressive osseointegration fixation for endoprosthetic reconstruction. Compressive osseointe - gration establishes stable fixation and integration through a nov
Externí odkaz:
https://doaj.org/article/914093f7697148038b1c9c51d634aa30
Autor:
M. H. Al-Mossawi, L. Chen, H. Fang, A. Ridley, J. de Wit, N. Yager, A. Hammitzsch, I. Pulyakhina, B. P. Fairfax, D. Simone, Yao Yi, S. Bandyopadhyay, K. Doig, R Gundle, B. Kendrick, F. Powrie, J. C. Knight, P. Bowness
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Spondyloarthritis is an inflammatory disease with Th17 cells implicated in the pathogenesis. Here the authors show that patients with spondyloarthritis have increased numbers of GM-CSF-secreting blood and synovial lymphocytes, Th17 or not, that carry
Externí odkaz:
https://doaj.org/article/1ce207c6c774466e8f0f97749494b098
Autor:
Duncan C. Ramsey, Jorge R. Walker, Rebecca Wetzel, Kenneth R. Gundle, James B. Hayden, Yee-Cheen Doung
Publikováno v:
Clinical Orthopaedics & Related Research. 480:2409-2417
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
Table of microinjected drugs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc7b60dd4f612c1719b4b938f3f115c
https://doi.org/10.1158/1078-0432.22477539.v1
https://doi.org/10.1158/1078-0432.22477539.v1
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
Microinjection of olaratumab does not inhibit PDGFRα, ERK, or S6 phosphorylation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e21e4c9b577eabda8261cdf9c16c3e0
https://doi.org/10.1158/1078-0432.22477542.v1
https://doi.org/10.1158/1078-0432.22477542.v1
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
All adverse events reported on the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35c5adbf368fd28def73541f84f8cfd0
https://doi.org/10.1158/1078-0432.22477536.v1
https://doi.org/10.1158/1078-0432.22477536.v1
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b87dedf9125fa69357f4ec88861afd
https://doi.org/10.1158/1078-0432.22477527.v1
https://doi.org/10.1158/1078-0432.22477527.v1
Autor:
Robert G. Maki, Richard A. Klinghoffer, Micah Ellison, Joyoti Dey, Jason Frazier, Emily Beirne, Kimberly H.W. Sottero, Marc O. Grenley, Jessica A. Bertout, William Kerwin, Daniel C. Ramirez, Mee-Young Lee, Jessica L. Davis, Matthew J. Thompson, Seth M. Pollack, Howard J. Goodman, Gary B. Deutsch, Kenneth R. Gundle
Distinct drug induced phenotypes and apoptotic responses specific to drug mechanism of action are seen at sites of CIVO microinjection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c94e647a6225c5c17f50ce28048d5d
https://doi.org/10.1158/1078-0432.22477554
https://doi.org/10.1158/1078-0432.22477554