Zobrazeno 1 - 10
of 677
pro vyhledávání: '"R, Grubb"'
Autor:
Weining Yin, Hannah L. Golliher, Amy J. Ferguson, Julia S. Kimbell, Alessandra Livraghi-Butrico, Troy D. Rogers, Barbara R. Grubb, Adam J. Kimple, Lawrence E. Ostrowski
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Background: Genetic defects in motile cilia cause primary ciliary dyskinesia (PCD), a rare disease with no specific therapeutics. Individuals with PCD often have impaired fertility and laterality defects and universally suffer from upper and lower ai
Externí odkaz:
https://doaj.org/article/7313cb29e11040f7ab3ac56f34fb3ca2
Autor:
Troy D. Rogers, Brian Button, Samir N. P. Kelada, Lawrence E. Ostrowski, Alessandra Livraghi-Butrico, Mark I. Gutay, Charles R. Esther, Barbara R. Grubb
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
As the nasal cavity is the portal of entry for inspired air in mammals, this region is exposed to the highest concentration of inhaled particulate matter and pathogens, which must be removed to keep the lower airways sterile. Thus, one might expect v
Externí odkaz:
https://doaj.org/article/8f11df437d0b4e6cbc966594a58fd2c5
Autor:
Matthew J. Reed, Neil R. Grubb, Christopher C. Lang, Rachel O'Brien, Kirsty Simpson, Mia Padarenga, Alison Grant, Sharon Tuck, Liza Keating, Frank Coffey, Lucy Jones, Tim Harris, Gavin Lloyd, James Gagg, Jason E. Smith, Tim Coats
Publikováno v:
EClinicalMedicine, Vol 8, Iss , Pp 37-46 (2019)
Background: Patients with palpitations and pre-syncope commonly present to Emergency Departments (EDs) but underlying rhythm diagnosis is often not possible during the initial presentation. This trial compares the symptomatic rhythm detection rate of
Externí odkaz:
https://doaj.org/article/08861aa74a7642c29fcced7b35e7ce7b
Autor:
Jie Xu, Alessandra Livraghi-Butrico, Xia Hou, Carthic Rajagopalan, Jifeng Zhang, Jun Song, Hong Jiang, Hong-Guang Wei, Hui Wang, Mohamad Bouhamdan, Jinxue Ruan, Dongshan Yang, Yining Qiu, Youming Xie, Ronald Barrett, Sharon McClellan, Hongmei Mou, Qingtian Wu, Xuequn Chen, Troy D. Rogers, Kristen J. Wilkinson, Rodney C. Gilmore, Charles R. Esther Jr., Khalequz Zaman, Xiubin Liang, Michael Sobolic, Linda Hazlett, Kezhong Zhang, Raymond A. Frizzell, Martina Gentzsch, Wanda K. O’Neal, Barbara R. Grubb, Y. Eugene Chen, Richard C. Boucher, Fei Sun
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
Existing animal models of cystic fibrosis (CF) have provided key insights into CF pathogenesis but have been limited by short lifespans, absence of key phenotypes, and/or high maintenance costs. Here, we report the CRISPR/Cas9-mediated generation of
Externí odkaz:
https://doaj.org/article/ff264f8cd5104415abd1eba07591062e
Autor:
Matthew J. Reed, Neil R. Grubb, Christopher C. Lang, Rachel O’Brien, Kirsty Simpson, Mia Padarenga, Alison Grant, Sharon Tuck
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-9 (2018)
Abstract Background Palpitations and pre-syncope are together responsible for 300,000 annual Emergency Department (ED) attendances in the United Kingdom (UK). Diagnosis of the underlying rhythm is difficult as many patients are fully recovered on ED
Externí odkaz:
https://doaj.org/article/59a564a092dd4ad0b4e13b0ccf0c86e7
Autor:
Nick B Spath, Kelvin Wang, Sowmya Venkatasumbramanian, Omar Fersia, David E Newby, Chris CE Lang, Neil R Grubb, Marc R Dweck
Publikováno v:
Open Heart, Vol 6, Iss 1 (2019)
Objectives Optimal right ventricular lead placement remains controversial. Large studies investigating the safety and long-term prognosis of apical and septal right ventricular lead placement have been lacking.Methods Consecutive patients undergoing
Externí odkaz:
https://doaj.org/article/6fc277379e5941f2952c1ecb02c2fb33
Publikováno v:
Life, Vol 11, Iss 5, p 430 (2021)
Mucociliary clearance (MCC) is a dominant component of pulmonary host defense. In health, the periciliary layer (PCL) is optimally hydrated, thus acting as an efficient lubricant layer over which the mucus layer moves by ciliary force. Airway surface
Externí odkaz:
https://doaj.org/article/22b9ca4970c1453d8e882a06125eda49
Autor:
Matthew James Reed, Hannah Brutin, Neil R. Grubb, Christopher C. Lang, Alasdair J. Gray, Kirsty Simpson, Allan MacRaild, Christopher J. Weir
Publikováno v:
Emergency Care Journal, Vol 14, Iss 2 (2018)
To investigate if Brain Natriuretic Peptide (BNP) and highsensitivity troponin I predict significant arrhythmia, symptomatic significant arrhythmia and 90-day death and/or Major Adverse Cardiac Event in Emergency Department (ED) unexplained syncope p
Externí odkaz:
https://doaj.org/article/b0bfbe54da5a4d88b2acc57e7ddfdee8
Publikováno v:
Journal of Police and Criminal Psychology. 37:195-211
Hostage and crisis negotiators are specialist police officers utilised internationally by police forces to resolve hostage and crisis incidents. Whilst the role has been heavily documented in some parts of the world (namely the United States of Ameri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b74c35aa0cc685096f0ce518fb799d1
https://doi.org/10.1007/s11896-021-09486-3
https://doi.org/10.1007/s11896-021-09486-3
Autor:
Wanda K. O'Neal, Rhianna E. Lee, Teresa M. Mascenik, Takanori Asakura, Hong Dang, Lisa C. Morton, Barbara R. Grubb, Hirotoshi Matsui, Martina Gentzsch, Richard C. Boucher, Carlton W Anderson, Kenichi Okuda, Gang Chen, Purushothama Rao Tata, Yvonne K. O’Neal, Satoko Nakano, Takahide Nagase, Yoshihiko Kobayashi, Michael Chua, Selene Margarita Barbosa Cardenas, Nancy L. Quinney, John C. Olsen, Andrew J. Ghio, Gianni Carraro, Caroline E Minnick, Lawrence E. Ostrowski, Rodney C. Gilmore, Takafumi Kato, Scott H. Randell, Barry R. Stripp, Weining Yin
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 203:1275-1289
Rationale: Identification of the specific cell types expressing CFTR (cystic fibrosis [CF] transmembrane conductance regulator) is required for precision medicine therapies for CF. However, a full ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df31dfc34267825f4278294c9b3077a9
https://doi.org/10.1164/rccm.202008-3198oc
https://doi.org/10.1164/rccm.202008-3198oc