Zobrazeno 1 - 10
of 232
pro vyhledávání: '"R, Gourley"'
Autor:
Jing Yang, Glenn R. Gourley, Adam Gilbertsen, Chi Chen, Lei Wang, Karen Smith, Marion Namenwirth, Libang Yang
Publikováno v:
Cells, Vol 13, Iss 3, p 236 (2024)
Hyperglycemia, lipotoxicity, and insulin resistance are known to increase the secretion of extracellular matrix from cardiac fibroblasts as well as the activation of paracrine signaling from cardiomyocytes, immune cells, and vascular cells, which rel
Externí odkaz:
https://doaj.org/article/81b9250985654c228d6e1e6220fcafad
Autor:
Nicholas M. Negretti, Christopher R. Gourley, Prabhat K. Talukdar, Geremy Clair, Courtney M. Klappenbach, Cody J. Lauritsen, Joshua N. Adkins, Michael E. Konkel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The pathogen Campylobacter jejuni invades intestinal cells after secreting protein effectors into the host cell cytosol via the flagellum. Here, Negretti et al. show that one of these effectors, CiaD, binds to host protein IQGAP1, thus leading to unc
Externí odkaz:
https://doaj.org/article/a8b8eb06bb7146fe925ceebb8d17162e
Publikováno v:
FPID Bulletin: The Bulletin of the Faculty for People with Intellectual Disabilities. 21:5-16
There is limited research into adults‘ experiences of being assessed and diagnosed with an intellectual disability (ID). We asked ten individuals referred to an adult learning disability health service for suspected ID, to complete a questionnaire
Autor:
Nicholas M Negretti, Yinyin Ye, Lais M Malavasi, Swechha M Pokharel, Steven Huynh, Susan Noh, Cassidy L Klima, Christopher R Gourley, Claude A Ragle, Santanu Bose, Torey Looft, Craig T Parker, Geremy Clair, Joshua N Adkins, Michael E Konkel
Publikováno v:
Gut Microbes, Vol 12, Iss 1 (2020)
The symptoms of infectious diarrheal disease are mediated by a combination of a pathogen’s virulence factors and the host immune system. Campylobacter jejuni is the leading bacterial cause of diarrhea worldwide due to its near-ubiquitous zoonotic a
Externí odkaz:
https://doaj.org/article/514f03e05aba4a3b83309a0d4398f590
Autor:
Nicholas M. Negretti, Geremy Clair, Prabhat K. Talukdar, Christopher R. Gourley, Steven Huynh, Joshua N. Adkins, Craig T. Parker, Colby M. Corneau, Michael E. Konkel
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Major foodborne bacterial pathogens, such as Campylobacter jejuni, have devised complex strategies to establish and foster intestinal infections. For more than two decades, researchers have used immortalized cell lines derived from human intestinal t
Externí odkaz:
https://doaj.org/article/0694950675a1409ab044eba5f886533f
Autor:
Jason L O'Loughlin, Tyson P Eucker, Juan D Chavez, Derrick R Samuelson, Jason Neal-McKinney, Christopher R Gourley, James E Bruce, Michael E Konkel
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118533 (2015)
Campylobacter jejuni is a leading bacterial cause of human gastroenteritis. The goal of this study was to analyze the C. jejuni F38011 strain, recovered from an individual with severe enteritis, at a genomic and proteomic level to gain insight into m
Externí odkaz:
https://doaj.org/article/a75237a0a4114a1383968169d881bd2b
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 114:e469
Publikováno v:
Cement and Concrete Research. 115:1-7
The use of pyrrhotite-containing aggregate in concrete has led to the premature deterioration of building foundations in Connecticut (U.S.A.). Pyrrhotite is a highly reactive iron-sulfide mineral that can initiate internal sulfate attack in concrete
Autor:
Cody J. Lauritsen, Christopher R. Gourley, Geremy Clair, Joshua N. Adkins, Nicholas M. Negretti, Prabhat K. Talukdar, Michael E. Konkel, Courtney M. Klappenbach
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications
Campylobacter jejuni is a foodborne pathogen that binds to and invades the epithelial cells lining the human intestinal tract. Maximal invasion of host cells by C. jejuni requires cell binding as well as delivery of the Cia proteins (Campylobacter in