Zobrazeno 1 - 10
of 1 162
pro vyhledávání: '"R, Gomis"'
Autor:
Jana R. Crespo, Natalia Martín-Martín, Saioa Garcia-Longarte, Jon Corres-Mendizabal, Onintza Carlevaris, Ianire Astobiza, Amaia Zabala-Letona, Marc Guiu, Mikel Azkargorta, Monika Gonzalez-Lopez, Nuria Macías-Cámara, Phuong Doan, Félix Elortza, Isabel Mendizabal, Jukka Westermack, Roger R. Gomis, Amaia Ercilla, Arkaitz Carracedo
Publikováno v:
Cell Death and Disease, Vol 15, Iss 7, Pp 1-11 (2024)
Abstract Prostate cancer exhibits high prevalence and accounts for a high number of cancer-related deaths. The discovery and characterization of molecular determinants of aggressive prostate cancer represents an active area of research. The Immediate
Externí odkaz:
https://doaj.org/article/9d77cf5d40a74212b0e4aa7821487081
Autor:
Jenniffer Linares, Anna Sallent-Aragay, Jordi Badia-Ramentol, Alba Recort-Bascuas, Ana Méndez, Noemí Manero-Rupérez, Daniele Lo Re, Elisa I. Rivas, Marc Guiu, Melissa Zwick, Mar Iglesias, Carolina Martinez-Ciarpaglini, Noelia Tarazona, Monica Varese, Xavier Hernando-Momblona, Adrià Cañellas-Socias, Mayra Orrillo, Marta Garrido, Nadia Saoudi, Elena Elez, Pilar Navarro, Josep Tabernero, Roger R. Gomis, Eduard Batlle, Jorge Pisonero, Andres Cervantes, Clara Montagut, Alexandre Calon
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Standard platinum-based chemotherapy is the basis of treatment of many cancers, however a proportion of patients do not derive benefit. Here the authors show that the platinum-based drug oxaliplatin accumulates in cancer-associated fibroblasts, activ
Externí odkaz:
https://doaj.org/article/6c73f8461c124a2ba8d43e933f393b91
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-5 (2022)
Abstract Policies in sunny countries, such as those in the Mediterranean area, do not promote vitamin D supplementation despite some studies might suggest the high prevalence of sub-optimal levels. The objective was to determine the vitamin D levels
Externí odkaz:
https://doaj.org/article/eab0c82258084de9840f240a3d7ff2e5
Autor:
Elisa I. Rivas, Jenniffer Linares, Melissa Zwick, Andrea Gómez-Llonin, Marc Guiu, Anna Labernadie, Jordi Badia-Ramentol, Anna Lladó, Lídia Bardia, Iván Pérez-Núñez, Carolina Martínez-Ciarpaglini, Noelia Tarazona, Anna Sallent-Aragay, Marta Garrido, Toni Celià-Terrassa, Octavio Burgués, Roger R. Gomis, Joan Albanell, Alexandre Calon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
A substantial proportion of HER2+ breast cancer patients do not benefit from HER2-targeted therapy. Here, the authors identify a population of cancer-associated fibroblasts involved in the suppression of trastuzumab-induced ADCC that can be pharmacol
Externí odkaz:
https://doaj.org/article/5a2417c908e3473699f39e6e2bb007ca
Autor:
E. García-Escobar, S. Valdés, F. Soriguer, J. Vendrell, I. M. Urrutia-Etxebarria, C. Maldonado-Araque, E. Ortega, P. Ocón, E. Montanya, E. Menéndez, A. Lago-Sampedro, T. González-Frutos, R. Gomis, A. Goday, S. García-Serrano, J. L. Galán-García, C. Castell, E. Bordiú, R. Badía, G. Aguilera-Venegas, J. Girbés, S. Gaztambide, E. Delgado, F. J. Chaves, L. Castaño, A. Calle-Pascual, G. Rojo-Martínez, J. Franch-Nadal
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Our aim was to evaluate whether fatty liver index (FLI) is associated with the risk of type 2 diabetes (T2DM) development within the Spanish adult population and according to their prediabetes status; additionally, to examine its incremental
Externí odkaz:
https://doaj.org/article/28b84e6f83be4b6e8c242034dfc860aa
Autor:
Fara Brasó-Maristany, Gaia Griguolo, Tomás Pascual, Laia Paré, Paolo Nuciforo, Antonio Llombart-Cussac, Begoña Bermejo, Mafalda Oliveira, Serafín Morales, Noelia Martínez, Maria Vidal, Barbara Adamo, Olga Martínez, Sonia Pernas, Rafael López, Montserrat Muñoz, Núria Chic, Patricia Galván, Isabel Garau, Luis Manso, Jesús Alarcón, Eduardo Martínez, Sara Gregorio, Roger R. Gomis, Patricia Villagrasa, Javier Cortés, Eva Ciruelos, Aleix Prat
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
HER2-enriched breast cancers within the HER2-positive subtype are addicted to the HER2 pathway. Here, the authors analyse gene expression before, during, and after treatment with anti-HER2-based therapies in the phase II PAMELA clinical trial, findin
Externí odkaz:
https://doaj.org/article/76ae9021acef4670a550a57d2950a303
Autor:
R.E. Coleman, M. Collinson, W. Gregory, H. Marshall, R. Bell, D. Dodwell, M. Keane, M. Gil, P. Barrett-Lee, D. Ritchie, A. Bowman, V. Liversedge, R.H. De Boer, J.L. Passos-Coelho, S. O'Reilly, G. Bertelli, J. Joffe, J.E. Brown, C. Wilson, J.C. Tercero, J. Jean-Mairet, R. Gomis, D. Cameron
Publikováno v:
Journal of Bone Oncology, Vol 13, Iss , Pp 123-135 (2018)
Adjuvant bisphosphonates improve disease outcomes in postmenopausal early breast cancer (EBC) but the long-term effects are poorly described. The AZURE trial (ISRCTN79831382) was designed to determine whether adjuvant zoledronic acid (ZOL) improves d
Externí odkaz:
https://doaj.org/article/97c01596da034c229da91e0ecbf0b075
Autor:
Ivan del Barco Barrantes, Camille Stephan-Otto Attolini, Konstantin Slobodnyuk, Ana Igea, Sara Gregorio, Sylwia Gawrzak, Roger R. Gomis, Angel R. Nebreda
Publikováno v:
Stem Cell Reports, Vol 10, Iss 1, Pp 257-271 (2018)
Summary: Mammary stem and progenitor cells are essential for mammary gland homeostasis and are also candidates for cells of origin of mammary tumors. Here, we have investigated the function of the protein kinase p38α in the mammary gland using mice
Externí odkaz:
https://doaj.org/article/1cdcb52fea14446297d22a6b3b3be2a8
Autor:
Mireia Olivan, Marta Garcia, Leticia Suárez, Marc Guiu, Laura Gros, Olga Méndez, Marina Rigau, Jaume Reventós, Miguel F. Segura, Inés de Torres, Jacques Planas, Xavier de la Cruz, Roger R. Gomis, Juan Morote, Ruth Rodríguez-Barrueco, Anna Santamaria
Publikováno v:
Cancers, Vol 13, Iss 24, p 6202 (2021)
About 70% of advanced-stage prostate cancer (PCa) patients will experience bone metastasis, which severely affects patients’ quality of life and progresses to lethal PCa in most cases. Hence, understanding the molecular heterogeneity of PCa cell po
Externí odkaz:
https://doaj.org/article/72cf3aba413245fb9db340fa9c79d997
Autor:
Naiara Perurena, Carolina Zandueta, Susana Martínez-Canarias, Haritz Moreno, Silvestre Vicent, Ana S. Almeida, Elisabet Guruceaga, Roger R. Gomis, Marta Santisteban, Mikala Egeblad, José Hermida, Fernando Lecanda
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Background Activated protein C/endothelial protein C receptor (APC/EPCR) axis is physiologically involved in anticoagulant and cytoprotective activities in endothelial cells. Emerging evidence indicates that EPCR also plays a role in breast
Externí odkaz:
https://doaj.org/article/34465a9e7ce04ad0b458592b725c8f37