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Akademický článek

Eat1-Like Alcohol Acyl Transferases From Yeasts Have High Alcoholysis and Thiolysis Activity

Autor: Constantinos Patinios, Lucrezia Lanza, Inge Corino, Maurice C. R. Franssen, John Van der Oost, Ruud A. Weusthuis, Servé W. M. Kengen

Publikováno v: Frontiers in Microbiology, Vol 11 (2020)

Esters are important flavor and fragrance compounds that are present in many food and beverage products. Many of these esters are produced by yeasts and bacteria during fermentation. While ester production in yeasts through the alcohol acyl transfera

Externí odkaz: https://doaj.org/article/0c9a853614fc4a778c6c788b71f4a344

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Akademický článek

Investigating the effectiveness of care delivery at an acute geriatric community hospital for older adults in the Netherlands: a protocol for a prospective controlled observational study

Autor: Rosanne van Seben, Marthe E Ribbink, Janet L Macneil-Vroomen, Irène Oudejans, R Franssen, W J Frenkel, M J Henstra, M A van Maanen, J L Parlevliet, E P van Poelgeest, M N Resodikromo, K J Kaland, N van der Velde, M E Visser, H C Willems

Publikováno v: BMJ Open, Vol 10, Iss 3 (2020)

IntroductionHospital admission in older adults with multiple chronic conditions is associated with unwanted outcomes like readmission, institutionalisation, functional decline and mortality. Providing acute care in the community and integrating effec

Externí odkaz: https://doaj.org/article/4ab40b3eb074498ea409062ebf6892ab

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Akademický článek

Kauniolide synthase is a P450 with unusual hydroxylation and cyclization-elimination activity

Autor: Qing Liu, Arman Beyraghdar Kashkooli, David Manzano, Irini Pateraki, Lea Richard, Pim Kolkman, Maria Fátima Lucas, Victor Guallar, Ric C.H. de Vos, Maurice C. R. Franssen, Alexander van der Krol, Harro Bouwmeester

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

Guaianolides are pharmaceutically interesting molecules. Here, the authors isolate the enzyme kauniolide synthase from feverfew, show that it converts constunolide into a guaianolide via an unusual mechanism of action, and reconstruct the full kaunio

Externí odkaz: https://doaj.org/article/2bca8e4a2e3b473f86c74e293fd3548d

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Robust Vaccine-Induced as Well as Hybrid B- and T-Cell Immunity across SARS-CoV-2 Vaccine Platforms in People with HIV

Autor: Myrthe L. Verburgh, Lisa van Pul, Marloes Grobben, Anders Boyd, Ferdinand W. N. M. Wit, Ad C. van Nuenen, Karel A. van Dort, Khadija Tejjani, Jacqueline van Rijswijk, Margreet Bakker, Lia van der Hoek, Maarten F. Schim van der Loeff, Marc van der Valk, Marit J. van Gils, Neeltje A. Kootstra, Peter Reiss, P. Reiss, F. W. N. M. Wit, M. van der Valk, A. Boyd, M. L. Verburgh, I. A. J. van der Wulp, M. C. Vanbellinghen, C. J. van Eeden, M. F. Schim van der Loeff, J. C. D. Koole, L. del Grande, I. Agard, S. Zaheri, M. M. J. Hillebregt, Y. M. C. Ruijs, D. P. Benschop, A. el Berkaoui, N. A. Kootstra, A. M. Harskamp-Holwerda, I. Maurer, M. M. Mangas Ruiz, B. D. N. Boeser-Nunnink, O. S. Starozhitskaya, L. van der Hoek, M. Bakker, M. J. van Gils, L. Dol, G. Rongen, S. E. Geerlings, A. Goorhuis, J. W. R. Hovius, F. J. B. Nellen, J. M. Prins, T. van der Poll, W. J. Wiersinga, M. van Vugt, G. de Bree, B. A. Lemkes, V. Spoorenberg, J. van Eden, F. J. J. Pijnappel, A. Weijsenfeld, S. Smalhout, I. J. Hylkema-van den Bout, C. Bruins, M. E. Spelbrink, P. G. Postema, P. H. L. T. Bisschop, E. Dekker, N. van der Velde, R. Franssen, J. M. R. Willemsen, L. Vogt, P. Portegies, G. J. Geurtsen, I. Visser, A. Schadé, P. T. Nieuwkerk, R. P. van Steenwijk, R. E. Jonkers, C. B. L. M. Majoie, M. W. A. Caan, B. J. H. van den Born, E. S. G. Stroes, S. van Oorspronk

Publikováno v: Microbiology Spectrum.

Few studies have comprehensively compared severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine-induced and hybrid B- and T-cell responses in people with HIV (PWH) to those in comparable controls without HIV. We included 195 PWH and 24

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f311c19c52f5b51a8b458a2e2467424c
https://doi.org/10.1128/spectrum.01155-23

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Changes to the trophic structure of a desert fish community following river regulation and species turnover: Implications for an endangered top predator

Autor: Eliza I. Gilbert, Nathan R. Franssen

Publikováno v: River Research and Applications.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::766e2d75751e712a1f1210130c5ce25b
https://doi.org/10.1002/rra.4128

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Akademický článek

Controlled Production of Zearalenone-Glucopyranoside Standards with Cunninghamella Strains Using Sulphate-Depleted Media

Autor: Jeroen Peters, Edward Ash, Arjen Gerssen, Ruud Van Dam, Maurice C. R. Franssen, Michel W. F. Nielen

Publikováno v: Toxins, Vol 13, Iss 6, p 366 (2021)

In recent years, conjugated mycotoxins have gained increasing interest in food safety, as their hydrolysis in human and animal intestines leads to an increase in toxicity. For the production of zearalenone (ZEN) glycosides reference standards, we app

Externí odkaz: https://doaj.org/article/a4bd5da112e04ebcb2e605e413e99090

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