Zobrazeno 1 - 10
of 1 232
pro vyhledávání: '"R, Dudley"'
Autor:
Augusto Faria Andrade, Alva Annett, Elham Karimi, Danai Georgia Topouza, Morteza Rezanejad, Yitong Liu, Michael McNicholas, Eduardo G. Gonzalez Santiago, Dhana Llivichuzhca-Loja, Arne Gehlhaar, Selin Jessa, Antonella De Cola, Bhavyaa Chandarana, Caterina Russo, Damien Faury, Geoffroy Danieau, Evan Puligandla, Yuhong Wei, Michele Zeinieh, Qing Wu, Steven Hebert, Nikoleta Juretic, Emily M. Nakada, Brian Krug, Valerie Larouche, Alexander G. Weil, Roy W. R. Dudley, Jason Karamchandani, Sameer Agnihotri, Daniela F. Quail, Benjamin Ellezam, Liza Konnikova, Logan A. Walsh, Manav Pathania, Claudia L. Kleinman, Nada Jabado
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Histone H3-mutant gliomas are deadly brain tumors characterized by a dysregulated epigenome and stalled differentiation. In contrast to the extensive datasets available on tumor cells, limited information exists on their tumor microenvironme
Externí odkaz:
https://doaj.org/article/69253d46aa2e495fb76b6cda5b46af80
Autor:
Marie-France Dorion, Diana Casas, Irina Shlaifer, Moein Yaqubi, Peter Fleming, Nathan Karpilovsky, Carol X.-Q. Chen, Michael Nicouleau, Valerio E. C. Piscopo, Emma J. MacDougall, Aeshah Alluli, Taylor M. Goldsmith, Alexandria Schneider, Samuel Dorion, Nathalia Aprahamian, Adam MacDonald, Rhalena A. Thomas, Roy W. R. Dudley, Jeffrey A. Hall, Edward A. Fon, Jack P. Antel, Jo Anne Stratton, Thomas M. Durcan, Roberta La Piana, Luke M. Healy
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-26 (2024)
Abstract Background Induced pluripotent stem cell-derived microglia (iMGL) represent an excellent tool in studying microglial function in health and disease. Yet, since differentiation and survival of iMGL are highly reliant on colony-stimulating fac
Externí odkaz:
https://doaj.org/article/aa6be16cdc4045c0b1747096bb52aa8a
Autor:
Florian Pernin, Qiao-Ling Cui, Abdulshakour Mohammadnia, Milton G. F. Fernandes, Jeffery A. Hall, Myriam Srour, Roy W. R. Dudley, Stephanie E. J. Zandee, Wendy Klement, Alexandre Prat, Hannah E. Salapa, Michael C. Levin, G. R. Wayne Moore, Timothy E. Kennedy, Christine Vande Velde, Jack P. Antel
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Oligodendrocyte (OL) injury and subsequent loss is a pathologic hallmark of multiple sclerosis (MS). Stress granules (SGs) are membrane-less organelles containing mRNAs stalled in translation and considered as participants of the cellular re
Externí odkaz:
https://doaj.org/article/7ecd4f332096485d86164c4aeb9e24fc
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 8, Pp 639-651 (2021)
Abstract Duchenne muscular dystrophy (DMD) is a genetic disorder that results in the absence of dystrophin, a cytoskeletal protein. Individuals with this disease experience progressive muscle destruction, which leads to muscle weakness. Studies have
Externí odkaz:
https://doaj.org/article/c296dd0e573b493c9639fae57959f01b
Publikováno v:
npj Digital Medicine, Vol 3, Iss 1, Pp 1-10 (2020)
Abstract Meningiomas are known to have relatively lower aggressiveness and better outcomes than other central nervous system (CNS) tumors. However, there is considerable overlap between clinical and radiological features characterizing benign, atypic
Externí odkaz:
https://doaj.org/article/8c580cb80a094cad8e4a04fe593e6768
Autor:
Lei Chen, Anweshan Samanta, Lin Zhao, Nathaniel R. Dudley, Tanner Buehler, Robert J. Vincent, Jeryl Hauptman, Magdy Girgis, Buddhadeb Dawn
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102272- (2021)
Summary: Although vitamin D3 (VitD3) prevents angiogenesis in cancer, VitD3 deficiency is associated with greater incidence of cardiovascular events in patients. We examined the influence of VitD3 on the angiogenic potential of mesenchymal stem cells
Externí odkaz:
https://doaj.org/article/0ebcb5869a2f4021b83c3b0a3df8a458
Autor:
Tenzin Gayden, Gabriel Crevier-Sorbo, Wajih Jawhar, Christine Saint-Martin, Robert Eveleigh, Mirko S. Gilardino, Natascia Anastasio, Yannis Trakadis, Angelia V. Bassenden, Albert M. Berghuis, Nada Jabado, Roy W. R. Dudley
Publikováno v:
Journal of Neurosurgery: Pediatrics. :1-9
OBJECTIVE The aim of this study was to characterize a novel pathogenic variant in the transient receptor potential vanilloid 4 (TRPV4) gene, causing familial nonsyndromic craniosynostosis (CS) with complete penetrance and variable expressivity. METHO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c3e6bf7219223be00d933f25d91c3c9
https://doi.org/10.3171/2023.1.peds22287
https://doi.org/10.3171/2023.1.peds22287
Autor:
Jorge M. Zuniga, Katsavelis Dimitrios, Jean L. Peck, Rakesh Srivastava, James E. Pierce, Drew R. Dudley, David A. Salazar, Keaton J. Young, Brian A. Knarr
Publikováno v:
Journal of NeuroEngineering and Rehabilitation, Vol 15, Iss 1, Pp 1-11 (2018)
Abstract Background Co-contraction is the simultaneous activation of agonist and antagonist muscles that produces forces around a joint. It is unknown if the use of a wrist-driven 3D printed transitional prostheses has any influence on the neuromuscu
Externí odkaz:
https://doaj.org/article/5ad45b846dcb46cebbc7ccd170d47ddb
Publikováno v:
The Journal of Sexual Medicine. 20
Introduction A novel oral testosterone replacement therapy (TRT), testosterone undecanoate (TU, JATENZO) has been shown in 1- and 2-year studies to have durable efficacy and safety. Hypogonadal men are heterogeneous with respect to age, body mass ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dc27e8121fd3ee24c87c4d6868d49d6
https://doi.org/10.1093/jsxmed/qdad060.368
https://doi.org/10.1093/jsxmed/qdad060.368