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Akademický článek

Tracer kinetic studies of the low density lipoprotein metabolism in the fetal rat: an example for estimation of flux rates in the nonsteady state.

Autor: D Plonné, B Schlag, L Winkler, R Dargel

Publikováno v: Journal of Lipid Research, Vol 31, Iss 5, Pp 747-752 (1990)

To get insight into the low density lipoprotein (LDL)-apoB flux in the rat fetus near term and in the early postnatal period, homologous apoE-free 125I-labeled LDL was injected into the umbilical vein of the rat fetus immediately after Caesarean sect

Externí odkaz: https://doaj.org/article/6e9f0264448641feb7a3e84f00448e61

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Akademický článek

Preparation of apoE-free rat low density lipoprotein for catabolic studies.

Autor: B Schlag, L Winkler, D Plonné, U Dürer, R Dargel

Publikováno v: Journal of Lipid Research, Vol 28, Iss 12, Pp 1521-1524 (1987)

The use of serum from rat fetuses instead of serum from adult rats for preparation of LDL by preparative ultracentrifugation leads to an LDL fraction containing apoB-100 and apoB-95 as the only protein moieties without need for any further purificati

Externí odkaz: https://doaj.org/article/3c01dc3e380c4e33b530267763eeed4a

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The lipid peroxidation end product 4‐hydroxy‐2,3‐nonenal up‐regulates transforming growth factor β1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis 1

Autor: Fiorella Biasi, Elena Chiarpotto, Simonetta Camandola, R Dargel, S Vogel, Antonella Scavazza, Gabriella Leonarduzzi, Giuseppe Poli

Publikováno v: The FASEB Journal. 11:851-857

An increasing number of reports underscore the frequent association of fibrosclerotic diseases of lung, liver, arterial wall, brain, etc., with the accumulation of oxidatively modified lipids and proteins. A cause-and-effect relationship has been pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21d00c0fd0d1da4d02fe59696c073904
https://doi.org/10.1096/fasebj.11.11.9285483

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Metabolism of leukotrienes is impaired in hepatocytes from rats with thioacetamide-induced liver cirrhosis

Autor: R. Dargel

Publikováno v: Prostaglandins, Leukotrienes and Essential Fatty Acids. 53:309-314

It is likely that the hepatocellular metabolism of potent mediators of inflammation is impaired in chronic liver injury. Therefore, in this study the degradation of the leukotrienes LTC4, LTE4 and LTB4 was investigated in isolated liver parenchymal c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ef8d3f79a4df50cfd09164d82a77e7
https://doi.org/10.1016/0952-3278(95)90131-0

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Varia

Publikováno v: Fresenius' Journal of Analytical Chemistry. 337:128-144

Fig. I. Time course of C-reactive protcin (CRP), panercatic seerctory trypsin inhibitor(PSTI), and neoplerin (mcan ± SEM) in polytraumalized patients. The patients were subdivided in three groups: lctal multiorgan failure (n = 11) x ---x; reversible

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19cc98a54d4591863746f83880bfdd0c
https://doi.org/10.1007/bf00325734

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Expression of insulin-like growth factor-I and insulin-like growth factor binding proteins during thioacetamide-induced liver cirrhosis in rats

Autor: Jens-Gerd Scharf, R. Novosyadlyy, R. Dargel

Publikováno v: Growth hormoneIGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. 15(5)

Objective The liver plays a central role in insulin-like growth factor (IGF) homeostasis providing the majority of circulating IGF-I and some of its binding proteins (IGFBPs). In liver cirrhosis the IGF axis is severely disturbed, and these alteratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8522d5885d036ceba97126a24a2d0ac6
https://pubmed.ncbi.nlm.nih.gov/16098781

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Luminol-and lucigenin-amplified chemiluminescence with rat liver microsomes. Kinetics and influence of ascorbic acid, glutathione, dimethylsulfoxide, N-t-butyl-a-phenyl-nitrone, copper-ions and a copper complex, catalase, superoxide dismutase, hexobarbital and aniline

Autor: W, Klinger, E, Karge, M, Kretzschmar, M, Rost, H P, Schulze, R, Dargel, C, Reinemann, H, Rein

Publikováno v: Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. 48(5)

For the investigation of luminol (LM)-and lucigenin (LC)-amplified chemiluminescence (CL) in rat liver microsomes using both a liquid-scintillation counter (LKB/Wallac 1219 Rackbeta) and a Berthold luminometer (AutoLumat LB 953) optimal incubation mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d661362c44608b69bb7d8b1513bcee21
https://pubmed.ncbi.nlm.nih.gov/8765690

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[Isolation and characterization of hepatocytes from chronic cholestatic damage to rat livers after bile duct ligation]

Autor: S, Hinz, A, Müller, G, Machnik, H, Franke, T, Zimmermann, R, Dargel

Publikováno v: Zeitschrift fur Gastroenterologie. 31

The aim of these investigations was the isolation and characterisation of hepatocytes from chronic injured rat livers after bile duct ligation. In three months old female Uje:WIST rats the distal common bile duct was double ligated. 14 days after the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::972f998fe7cb5b6e88851456e274f91b
https://pubmed.ncbi.nlm.nih.gov/7483707

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Stimulation of bile flow and inhibition of biliary secretion of taurocholate and leukotriene C4 in thioacetamide-induced liver fibrosis

Autor: D, Müller, E, Dietze, R, Dargel, H, Krell

Publikováno v: Zeitschrift fur Gastroenterologie. 31

In order to study the relation of hepatic fibrogenesis to biliary elimination, female Uje:WIST rats were treated with thioacetamide (TAA). This treatment results in single cell necrosis, fibrosis, nodular parenchyma und proliferation of bile ducts. I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::734abdc62e1443ead342ae651cd0cd0f
https://pubmed.ncbi.nlm.nih.gov/7483705

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[Microsomal phospholipid pattern and liver ultrastructure of aging rats following treatment with essential phospholipids]

Autor: R, Dargel, T, Zimmermann, H, Franke, V, Buko

Publikováno v: Gastroenterologisches Journal : Organ der Gesellschaft fur Gastroenterologie der DDR. 51(2)

The treatment of aging rats with 100 or 300 mg/kg "essential" phospholipids (EPL) for 10 weeks significantly changed the microsomal concentration of phosphatidyl serine plus phosphatidyl inositol. The most marked alterations of the phospholipid fatty

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d7afe1c0394a8a2ade9413cd59c2e75
https://pubmed.ncbi.nlm.nih.gov/1755950

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