Zobrazeno 1 - 10
of 6 896
pro vyhledávání: '"R, Cox"'
Autor:
Danni A. Gadd, Hannah M. Smith, Donncha Mullin, Ola Chybowska, Robert F. Hillary, Dorien M. Kimenai, Elena Bernabeu, Yipeng Cheng, Chloe Fawns-Ritchie, Archie Campbell, Danielle Page, Adele Taylor, Janie Corley, Maria Del C. Valdés-Hernández, Susana Muñoz Maniega, Mark E. Bastin, Joanna M. Wardlaw, Rosie M. Walker, Kathryn L. Evans, Andrew M. McIntosh, Caroline Hayward, Tom C. Russ, Sarah E. Harris, Paul Welsh, Naveed Sattar, Simon R. Cox, Daniel L. McCartney, Riccardo E. Marioni
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Plasma growth differentiation factor 15 (GDF15) and N‐terminal proB‐type natriuretic peptide (NT‐proBNP) are cardiovascular biomarkers that associate with a range of diseases. Epigenetic scores (EpiScores) for GDF15 and NT-p
Externí odkaz:
https://doaj.org/article/76e8233ab631452ab514eb985f52d351
Autor:
James R. Cox, Ehad Akeila, Alberto P. Avolio, Mark Butlin, Catherine Liao, Gisele J. Bentley, Ahmad Qasem
Publikováno v:
Pulse, Vol 12, Iss 1, Pp 95-105 (2024)
Introduction: Central aortic pressure waveform analyses can provide clinically relevant information beyond conventional brachial blood pressure (BP) assessment. This waveform can be reproduced noninvasively through application of a generalized transf
Externí odkaz:
https://doaj.org/article/1418b38a4de34a1681da6eba19a5f0d4
Autor:
Katie Mckinnon, Eleanor L. S. Conole, Kadi Vaher, Robert F. Hillary, Danni A. Gadd, Justyna Binkowska, Gemma Sullivan, Anna J. Stevenson, Amy Corrigan, Lee Murphy, Heather C. Whalley, Hilary Richardson, Riccardo E. Marioni, Simon R. Cox, James P. Boardman
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-14 (2024)
Abstract Background Epigenetic scores (EpiScores), reflecting DNA methylation (DNAm)-based surrogates for complex traits, have been developed for multiple circulating proteins. EpiScores for pro-inflammatory proteins, such as C-reactive protein (DNAm
Externí odkaz:
https://doaj.org/article/a9cea3b05e5c4db6b4d9d4b171d871d0
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Frailty is a complex trait. Twin studies and high-powered Genome Wide Association Studies conducted in the UK Biobank have demonstrated a strong genetic basis of frailty. The present study utilized summary statistics from a Genome Wide Assoc
Externí odkaz:
https://doaj.org/article/0f6a3ca14720400fae9492624b63f56f
Autor:
Sjaan R Gomersall, Wendy J Brown, Jeff S Coombes, Shelley E Keating, Nicola W Burton, Robert G Fassett, Veronique S Chachay, Matthew D Hordern, Trishan Gajanand, Emily R Cox
Publikováno v:
BMJ Open Sport & Exercise Medicine, Vol 10, Iss 4 (2024)
Objective The objective of this study was to compare the effects of novel, time-efficient, low-volume combined aerobic and resistance high-intensity interval training (C-HIIT), and current exercise guidelines (210 min/week of combined moderate-intens
Externí odkaz:
https://doaj.org/article/24cc9284cc0b4124a827bc6770ffe627
Autor:
Maxim N. Shokhirev, Daniel J. Kramer, Janie Corley, Simon R. Cox, Trinna L. Cuellar, Adiv A. Johnson
Publikováno v:
Frontiers in Aging, Vol 5 (2024)
While earlier first-generation epigenetic aging clocks were trained to estimate chronological age as accurately as possible, more recent next-generation clocks incorporate DNA methylation information more pertinent to health, lifestyle, and/or outcom
Externí odkaz:
https://doaj.org/article/f4b4f1b4321c421aa2658ccd019d25a7
Autor:
Anna K. Jansson, David R. Lubans, Mitch J. Duncan, Jordan J. Smith, Adrian Bauman, John Attia, Sara L. Robards, Emily R. Cox, Sam Beacroft, Ronald C. Plotnikoff
Publikováno v:
Contemporary Clinical Trials Communications, Vol 41, Iss , Pp 101358- (2024)
Background: In this paper we outline the protocol for an implementation-effectiveness trial of ecofit, a multi-component mHealth intervention aimed at increasing participation in resistance and aerobic physical activity using the outdoor built enviro
Externí odkaz:
https://doaj.org/article/81cd344ed06d4074ae3749fce95be4a1
Autor:
Neena Modi, Sarah J Stock, James P Boardman, Ruth Andrew, G David Batty, Athanasios Tsanas, Cheryl Battersby, Riccardo E Marioni, Jill Hall, Michael J Thrippleton, Rebecca M Reynolds, Mark E Bastin, Simon R Cox, Lee Murphy, Heather C Whalley, Hilary Richardson, Alan J Quigley, Manuel Blesa Cábez, Lauren Ingledow
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Introduction Preterm birth (PTB) is strongly associated with encephalopathy of prematurity (EoP) and neurocognitive impairment. The biological axes linking PTB with atypical brain development are uncertain. We aim to elucidate the roles of neuroendoc
Externí odkaz:
https://doaj.org/article/659350e489234fb4bd93a47faaef04d5
Autor:
Danielle McCartney, Christopher Irwin, Zeeta Bawa, Blake Palmer, Ayshe Sahinovic, Nathan Delang, Gregory R. Cox, Ben Desbrow, Namson S. Lau, Iain S. McGregor
Publikováno v:
Sports Medicine - Open, Vol 10, Iss 1, Pp 1-15 (2024)
Abstract Background Exercise is known to improve health. However, it can be unpleasant, often inducing negative feelings, or ‘affect’. Cannabidiol (CBD), a non-intoxicating constituent of the cannabis plant, has been reported to enhance the subje
Externí odkaz:
https://doaj.org/article/ba9def7abdb54c56bfe14c6c18f5f908
Autor:
Hannah M. Smith, Joanna E. Moodie, Karla Monterrubio-Gómez, Danni A. Gadd, Robert F. Hillary, Aleksandra D. Chybowska, Daniel L. McCartney, Archie Campbell, Paul Redmond, Danielle Page, Adele Taylor, Janie Corley, Sarah E. Harris, Maria Valdés Hernández, Susana Muñoz Maniega, Mark E. Bastin, Joanna M. Wardlaw, Ian J. Deary, James P. Boardman, Donncha S. Mullin, Tom C. Russ, Simon R. Cox, Riccardo E. Marioni
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-10 (2024)
Abstract Background Epigenetic Scores (EpiScores) for blood protein levels have been associated with disease outcomes and measures of brain health, highlighting their potential usefulness as clinical biomarkers. They are typically derived via penalis
Externí odkaz:
https://doaj.org/article/3c13220e7e174e5f8add934cd767d03c