Zobrazeno 1 - 10
of 160
pro vyhledávání: '"R, Counsell"'
Autor:
Zehan Zhang, John R. Counsell
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101221- (2024)
Externí odkaz:
https://doaj.org/article/44053127898f43a197dcb3127b6a669a
Autor:
Auxtine Micalet, Luke J. Tappouni, Katarzyna Peszko, Despoina Karagianni, Ashley Lam, John R. Counsell, Sergio A. Quezada, Emad Moeendarbary, Umber Cheema
Publikováno v:
Matrix Biology Plus, Vol 19, Iss , Pp 100137- (2023)
Background: Cancer cells remodel their local physical environment through processes of matrix reorganisation, deposition, stiffening and degradation. Urokinase-type plasminogen activator (uPA), which is encoded by the PLAU gene, is an extracellular p
Externí odkaz:
https://doaj.org/article/d717ce246c6c4b19a2effb52e7212958
Autor:
Allison R. Julien, Kristen R. Counsell, Isabella J. Burger, Andrew J. Kouba, Diane Barber, Cassidi Cobos, Randy D. Jennings, Bruce L. Christman, Carrie K. Kouba
Publikováno v:
Conservation Science and Practice, Vol 5, Iss 1, Pp n/a-n/a (2023)
Abstract The Chiricahua leopard frog (Lithobates chiricahuensis) is a threatened species endemic to the southwestern United States and Northern Mexico. Captive breeding programs were established to support reintroduction efforts, yet reproductive out
Externí odkaz:
https://doaj.org/article/5057959381304f5c813ef17741957032
Autor:
John R. Counsell, Guillaume De Brabandere, Rajvinder Karda, Marc Moore, Antonio Greco, Alysha Bray, Juan Antinao Diaz, Dany P. Perocheau, Ulrike Mock, Simon N. Waddington
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 357-365 (2021)
Lentiviral (LV) vectors based on human immunodeficiency virus type I (HIV-1) package two copies of their single-stranded RNA into vector particles. Normally, this RNA genome is reverse transcribed into a double-stranded DNA provirus that integrates i
Externí odkaz:
https://doaj.org/article/91dfe80765324ae6b172bc6c3bfd05e5
Autor:
Isabella Burger, Allison R. Julien, Andrew J. Kouba, Diane Barber, Kristen R. Counsell, Carlos Pacheco, Jessi Krebs, Carrie K. Kouba
Publikováno v:
Conservation Science and Practice, Vol 3, Iss 11, Pp n/a-n/a (2021)
Abstract Genetic variation of the endangered Puerto Rican crested toad (PRCT; Peltophryne lemur) has dwindled over time in both wild and captive populations, leading to long‐term sustainability issues for the recovery program. To address this chall
Externí odkaz:
https://doaj.org/article/76788fb69db9499d98094b47a736b730
Autor:
Luca Pinton, Moustafa Khedr, Valentina M. Lionello, Shilpita Sarcar, Sara M. Maffioletti, Sumitava Dastidar, Elisa Negroni, SungWoo Choi, Noreen Khokhar, Anne Bigot, John R. Counsell, Andreia Sofia Bernardo, Peter S. Zammit, Francesco Saverio Tedesco
Publikováno v:
Nature Protocols. 18:1337-1376
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fadf217c330c1b3256dec4924faacfe
https://doi.org/10.1038/s41596-022-00790-8
https://doi.org/10.1038/s41596-022-00790-8
Autor:
Maëlle Lorvellec, Alessandro Filippo Pellegata, Alice Maestri, Chiara Turchetta, Elena Alvarez Mediavilla, Soichi Shibuya, Brendan Jones, Federico Scottoni, Dany P. Perocheau, Andrei Claudiu Cozmescu, Juliette M. Delhove, Daniel Kysh, Asllan Gjinovci, John R. Counsell, Wendy E. Heywood, Kevin Mills, Tristan R. McKay, Paolo De Coppi, Paul Gissen
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101808- (2020)
Summary: Explosion of gene therapy approaches for treating rare monogenic and common liver disorders created an urgent need for disease models able to replicate human liver cellular environment. Available models lack 3D liver structure or are unable
Externí odkaz:
https://doaj.org/article/c043e3e17edd419a9dda615cee1a696f
Autor:
Chioma Izzi-Engbeaya, Yue Ma, Niki W. Buckley, Risheka Ratnasabapathy, Errol Richardson, John R. Counsell, Isabel Fernandes-Freitas, Mariana Norton, Gala Farooq, Zainab Mirza, Mingzhu Cai, Sharon Cheetham, Jonathan Seckl, Kevin Murphy, Waljit S. Dhillo, James Gardiner
Publikováno v:
Molecular Metabolism, Vol 36, Iss , Pp - (2020)
Objective: Obesity is a major cause of morbidity and mortality. Few weight-reducing medications are available, and these have limited efficacy. Cushing's Syndrome (caused by elevated glucocorticoid levels) and obesity have similar metabolic features.
Externí odkaz:
https://doaj.org/article/93c7b4921eff4f49941fd156d8b4926c
Autor:
John R. Counsell, Rajvinder Karda, Juan Antinao Diaz, Louise Carey, Tatiana Wiktorowicz, Suzanne M.K. Buckley, Shima Ameri, Joanne Ng, Julien Baruteau, Filipa Almeida, Rohan de Silva, Roberto Simone, Eleonora Lugarà, Gabriele Lignani, Dirk Lindemann, Axel Rethwilm, Ahad A. Rahim, Simon N. Waddington, Steven J. Howe
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 626-634 (2018)
Viral vectors are rapidly being developed for a range of applications in research and gene therapy. Prototype foamy virus (PFV) vectors have been described for gene therapy, although their use has mainly been restricted to ex vivo stem cell modificat
Externí odkaz:
https://doaj.org/article/6238edf25cf544478737c499f40dbd36
Autor:
Rajvinder Karda, Dany P. Perocheau, Natalie Suff, Joanne Ng, Juliette M. K. M. Delhove, Suzanne M. K. Buckley, Samantha Richards, John R. Counsell, Henrik Hagberg, Mark R. Johnson, Tristan R. McKay, Simon N. Waddington
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Luciferase bioimaging in living animals is increasingly being applied in many fields of biomedical research. Rodent imaging usually involves anaesthetising the animal during data capture, however, the biological consequences of anaesthesia h
Externí odkaz:
https://doaj.org/article/9f6f64e65ad641139897de92958624f7