Zobrazeno 1 - 10
of 316
pro vyhledávání: '"R, Colten"'
Autor:
Institute of Medicine, Board on Health Sciences Policy, Committee on Sleep Medicine and Research, Bruce M. Altevogt, Harvey R. Colten
Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorde
Autor:
H R Colten
Publikováno v:
Immunology today. 4(5)
The structure, organization and control of the expression of complement genes is now being studied at the RNA and DNA levels. This work was prompted by recognized genetic polymorphisms and complement deficiencies in humans and animals. Here Harvey Co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9474dac2633e5186b876e3cb93a8d31
https://pubmed.ncbi.nlm.nih.gov/25291675
https://pubmed.ncbi.nlm.nih.gov/25291675
Autor:
Harvey R. Colten, Béla Z. Schmidt
Publikováno v:
Immunological Reviews. 178:166-176
The biological activities of the more than 30 proteins that comprise the complement system have been elucidated in parallel lines of investigation that resulted in the purification of the proteins and studies of their function in vitro. Twenty years
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f694819945a5a152653ad67e79b80d92
https://doi.org/10.1034/j.1600-065x.2000.17801.x
https://doi.org/10.1034/j.1600-065x.2000.17801.x
Autor:
Claude Libert, Bernardo Grijalba, Wim Van Molle, Elisabeth Kremmer, Peter Brouckaert, Harvey R Colten, Ben Wielockx, Walter Fiers
Publikováno v:
Cytokine. 11:617-625
Injection of tumour necrosis factor (TNF) in animals causes severe liver cell toxicity, especially when D-(+)-galactosamine (GalN) is co-administered. After challenge with TNF/GalN, serum complement activity (CH50 and APCH50) decreased dramatically,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9786bd4986c81dcb6fe3e025106c580
https://doi.org/10.1006/cyto.1998.0462
https://doi.org/10.1006/cyto.1998.0462
Autor:
Gérard Garnier, David E. Briles, Tünde Hidvégi, Harvey R. Colten, Antonella Circolo, Rick A. Wetsel, John E Volanakis, Xeufeng Wang, Alexander J. Szalai, Wataru Fukuda
Publikováno v:
Immunopharmacology. 42:135-149
Genetic deficiencies of the complement protein C3 occur naturally in humans and animal models and have been induced in mice by targeted deletion of the C3 gene. The study of these deficiencies has provided evidence for C3 functions in immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d22e1ec41e0c6bf6ebfdc0aa10829dc
https://doi.org/10.1016/s0162-3109(99)00021-1
https://doi.org/10.1016/s0162-3109(99)00021-1
Publikováno v:
Journal of Biological Chemistry. 274:11782-11788
Factor H, a secretory glycoprotein composed of 20 short consensus repeat modules, is an inhibitor of the complement system. Previous studies of inherited factor H deficiency revealed single amino acid substitutions at conserved cysteine residues, on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b27d7d9694ef64e4d989a7c36a7c942
https://doi.org/10.1074/jbc.274.17.11782
https://doi.org/10.1074/jbc.274.17.11782
Autor:
Marja-Liisa Lokki, Antonella Circolo, Pirkko Ahokas, Kristi L. Rupert, C. Yung Yu, Harvey R. Colten
Publikováno v:
The Journal of Immunology. 162:3687-3693
The complement protein C4, encoded by two genes (C4A and C4B) on chromosome 6p, is the most polymorphic among the MHC III gene products. We investigated the molecular basis of C4 deficiency in a Finnish woman with systemic lupus erythematosus. C4-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25e78f5c1809d8dc09e260e05a244d4c
https://doi.org/10.4049/jimmunol.162.6.3687
https://doi.org/10.4049/jimmunol.162.6.3687
Autor:
Liyang Wang, Gary H. Cohen, Athena M. Soulika, Roselyn J. Eisenberg, Reinhard Burger, Harvey R. Colten, John M. Lubinski, Rick A. Wetsel, John D. Lambris, Harvey M. Friedman
Publikováno v:
Journal of Virology. 72:8257-8263
Many microorganisms encode proteins that interact with molecules involved in host immunity; however, few of these molecules have been proven to promote immune evasion in vivo. Herpes simplex virus type 1 (HSV-1) glycoprotein C (gC) binds complement c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806f3943faed821cd292344fe3fee1ec
https://doi.org/10.1128/jvi.72.10.8257-8263.1998
https://doi.org/10.1128/jvi.72.10.8257-8263.1998
Autor:
Xuefeng Wang, Antonella Circolo, Marja Liisa Lokki, Harvey R. Colten, P. G. Shackelford, Rick A. Wetsel
Publikováno v:
Immunology. 93:184-191
Deficiency of the complement protein C2 (C2D), one of the most common genetic deficiencies of the complement system, is associated with rheumatological disorders and increased susceptibility to infection. Two types of C2D have been recognized, each i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0a2451bcca1de74b878b35a4b6741d4
https://doi.org/10.1046/j.1365-2567.1998.00392.x
https://doi.org/10.1046/j.1365-2567.1998.00392.x