Zobrazeno 1 - 10
of 113
pro vyhledávání: '"R, Ciabatti"'
Publikováno v:
European Journal of Medicinal Chemistry. 32:459-478
Summary Resistance to the glycopeptide antibiotics vancomycin (V) and teicoplanin (T) in multi-resistant Gram-positive pathogens, particularly enterococci, is becoming a dramatic nosocomial problem. Besides the current lack of efficacious alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14a8b60333e44cba86f8dedfa8bb6e33
https://doi.org/10.1016/s0223-5234(97)84010-x
https://doi.org/10.1016/s0223-5234(97)84010-x
Autor:
A. Malabarba, R. Ciabatti
Publikováno v:
ChemInform. 28
Glycopeptides are a class of naturally occurring antibiotics produced by fermentation of microorganisms. They inhibit cell wall biosynthesis in bacteria by forming a complex with the C-terminal D-alanyl-D-alanine of growing peptidoglycan chains. Glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a67cbbdc4f5c07e2e58875f1517b386
https://doi.org/10.1002/chin.199743317
https://doi.org/10.1002/chin.199743317
Publikováno v:
ChemInform. 28
Summary Resistance to the glycopeptide antibiotics vancomycin (V) and teicoplanin (T) in multi-resistant Gram-positive pathogens, particularly enterococci, is becoming a dramatic nosocomial problem. Besides the current lack of efficacious alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::983cbd25ca3fbae7949b6a42b15d7cec
https://doi.org/10.1002/chin.199743302
https://doi.org/10.1002/chin.199743302
Autor:
R, Ciabatti, A, Malabarba
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 52(5)
Glycopeptides are a class of naturally occurring antibiotics produced by fermentation of microorganisms. They inhibit cell wall biosynthesis in bacteria by forming a complex with the C-terminal D-alanyl-D-alanine of growing peptidoglycan chains. Glyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f9e26b5858b31243d61b50e862e7c872
https://pubmed.ncbi.nlm.nih.gov/9274002
https://pubmed.ncbi.nlm.nih.gov/9274002
Autor:
A Iu, Pavlov, E N, Olsuf'eva, O V, Miroshnikova, M I, Reznikova, E I, Lazhko, A, Malabarba, R, Ciabatti, M N, Preobrazhenskaia
Publikováno v:
Bioorganicheskaia khimiia. 23(5)
A new approach for the modification of the heptapeptide core of glycopeptide antibiotics was proposed based on the replacement of amino acid residues in positions 1 and 3 in teicoplanin aglycone and in position 1 in the eremomycin aglycone. Six novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::238d459817baf37b522d835504d247f8
https://pubmed.ncbi.nlm.nih.gov/9290051
https://pubmed.ncbi.nlm.nih.gov/9290051
Autor:
A. Malabarba, R. Ciabatti
The increased interest for glycopeptides is related to the increasing incidence of serious and often multi-resistant Gram-positive pathogens infecting hospital patients, such as the difficult-to-treat methicillin-resistant (Meth-R) Staphylococcus aur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26419bcae985c7fadc5847ce09525f4
https://doi.org/10.1016/s0165-7208(97)80076-1
https://doi.org/10.1016/s0165-7208(97)80076-1
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 51(7)
Purpuromycin (1) is a natural antibiotic with a broad spectrum of activity encompassing bacteria, fungi and protozoa. A new series of derivatives of 1 was prepared by the modification or replacement of the C-4 hydroxyl group. The physico-chemical cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ccab17a788a9faf909c8d7510ca18fb9
https://pubmed.ncbi.nlm.nih.gov/8765673
https://pubmed.ncbi.nlm.nih.gov/8765673
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 48(5)
Purpuromycin, isolated in our laboratories from the culture broth of Actinoplanes ianthinogenes, is very active in vitro against Gram-positive bacteria and fungi and shows variable activity against Gram-negative bacteria. Its poor bioavailability, pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf6edf00feacabb77b59228f543dcc04
https://pubmed.ncbi.nlm.nih.gov/8343211
https://pubmed.ncbi.nlm.nih.gov/8343211
Publikováno v:
Drugs under experimental and clinical research. 16(9)
Ramoplanin is a novel antibacterial agent with characteristics that make it suitable for development as a topical treatment for acne, infected wounds, and for treatment of antibiotic-associated diarrhoea. In this paper, the authors will review the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04f555c51a1801663425fc739a1f8389
https://pubmed.ncbi.nlm.nih.gov/2100246
https://pubmed.ncbi.nlm.nih.gov/2100246
Publikováno v:
Chemischer Informationsdienst. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b4ffa515f1e6793cebd35837a5f59ea
https://doi.org/10.1002/chin.198232332
https://doi.org/10.1002/chin.198232332