Zobrazeno 1 - 10
of 713
pro vyhledávání: '"R, Chong"'
Autor:
Jiangbo Cui, Caroline Robert, Chia May Teh, Eddie Chong Jun Yi, Joyce R. Chong, Boon Yeow Tan, Narayanaswamy Venketasubramanian, Mitchell K. P. Lai, Christopher Chen, Saima Hilal
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background Cognitive impairment is an increasingly recognized comorbidity of diabetes, yet the mechanisms underlying this association remain poorly understood. This knowledge gap has contributed to conflicting findings regarding the impact o
Externí odkaz:
https://doaj.org/article/2b51c5a2c02f4d57b16b6fe58bc01ea7
Autor:
Guido Ghilardi, Luca Paruzzo, Vrutti Patel, Jakub Svoboda, Emeline R. Chong, Eugenio Fardella, Elise A. Chong, Giulia Gabrielli, Sunita D. Nasta, Daniel J. Landsburg, Jordan Carter, Raymone Pajarillo, Stefan K. Barta, Griffin White, Elizabeth Weber, Ellen Napier, David L. Porter, Alfred L. Garfall, Stephen J. Schuster, Marco Ruella
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-5 (2024)
Abstract Bendamustine has been retrospectively shown to be an effective and safe lymphodepletion regimen prior to the anti-CD19 chimeric antigen receptor T cell (CART) products tisagenlecleucel and axicabtagene ciloleucel, as well as the anti-BCMA CA
Externí odkaz:
https://doaj.org/article/7841086f48d141fcacd16214fbafb379
Autor:
Nazia Pathan, Wei Q. Deng, Matteo Di Scipio, Mohammad Khan, Shihong Mao, Robert W. Morton, Ricky Lali, Marie Pigeyre, Michael R. Chong, Guillaume Paré
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract It has been postulated that rare coding variants (RVs; MAF 5%, with height having the highest h 2 RV at 21.9% (95% CI: 19.0-24.8%). The total heritability, including common and rare variants, recovered pedigree-based estimates for 11 traits.
Externí odkaz:
https://doaj.org/article/c178b4267dff4643bed6e59ce258ffbb
Autor:
Xin Ying Chua, Federico Torta, Joyce R. Chong, Narayanaswamy Venketasubramanian, Saima Hilal, Markus R. Wenk, Christopher P. Chen, Thiruma V. Arumugam, Deron R. Herr, Mitchell K. P. Lai
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Alzheimer’s disease (AD) and vascular dementia (VaD) are two of the commonest causes of dementia in the elderly. Of the myriad biomolecules implicated in dementia pathogenesis, sphingolipids have attracted relatively scant resea
Externí odkaz:
https://doaj.org/article/504a7fb1e0244d43871ae662fd979401
Autor:
Joyce R. Chong, Yuek Ling Chai, Amelia T. Y. Yam, Saima Hilal, Henri Vrooman, Narayanaswamy Venketasubramanian, Kaj Blennow, Henrik Zetterberg, Nicholas J. Ashton, Christopher P. Chen, Mitchell K. P. Lai
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 2, Pp n/a-n/a (2024)
Abstract INTRODUCTION While elevated blood glial fibrillary acidic protein (GFAP) has been associated with brain amyloid pathology, whether this association occurs in populations with high cerebral small vessel disease (CSVD) concomitance remains unc
Externí odkaz:
https://doaj.org/article/847dff28cdd24ebbb6c6125076d11e68
Autor:
Yuek Ling Chai, Jasinda H. Lee, Joyce R. Chong, Clive Ballard, Paul T. Francis, Brian K. Kennedy, Thiruma V. Arumugam, Christopher P. Chen, Dag Aarsland, Mitchell K. P. Lai
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background Chronically dysregulated neuroinflammation has been implicated in neurodegenerative dementias, with separate studies reporting increased brain levels of inflammatory mediators and gliosis in Alzheimer’s disease (AD) as well as i
Externí odkaz:
https://doaj.org/article/2a5cf1b0ed4d4f41a68dd14770553323
Autor:
Rachel S. L. Chia, Karolina Minta, Liu-Yun Wu, Kaung H. T. Salai, Yuek Ling Chai, Saima Hilal, Narayanaswamy Venketasubramanian, Christopher P. Chen, Joyce R. Chong, Mitchell K. P. Lai
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 75 (2024)
In the brain, the extracellular matrix (ECM) composition shapes the neuronal microenvironment and can undergo substantial changes with cerebral pathology. Brevican is integral to the formation of the ECM’s neuroprotective perineuronal nets (PNNs).
Externí odkaz:
https://doaj.org/article/c47e21c8d23048429fbcd19466f740e8
Publikováno v:
Biosurface and Biotribology, Vol 8, Iss 2, Pp 121-128 (2022)
Abstract With one‐third of patients having osteoarthritis predominantly in one compartment of the knee, unicompartmental knee spacers have been introduced as a less invasive alternative to total knee replacement. However, patients with the knee spa
Externí odkaz:
https://doaj.org/article/b5494be4eba840d2a22eb41df3df101d
Autor:
Joyce R. Chong, Saima Hilal, Nicholas J. Ashton, Thomas K. Karikari, Anthonin Reilhac, Henri Vrooman, Michael Schöll, Henrik Zetterberg, Kaj Blennow, Christopher P. Chen, Mitchell K. P. Lai
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 1, Pp n/a-n/a (2023)
Abstract Introduction Plasma neurofilament light chain (NfL) is a potential biomarker for neurodegeneration in Alzheimer's disease (AD), ischemic stroke, and non‐dementia cohorts with cerebral small vessel disease (CSVD). However, studies of AD in
Externí odkaz:
https://doaj.org/article/eaeb727ebf9341b1bcc25a03be027817
Autor:
C. C. Yu, E. J. Koh, J. A. Low, M. L. Ong, A. G. H. Sim, D. Y. Q. Hong, R. Chong, J. Low, R. Ng
Publikováno v:
BMC Medical Education, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background This study evaluated the impact of the adapted version of the Respecting Choices® The Living Matters Advance Care Planning (ACP) facilitator training programme on trainees’ attitudes on facilitation 6 months post-training. Sett
Externí odkaz:
https://doaj.org/article/2d37e2e1ba784dbdb50e1413a12d33bc