Zobrazeno 1 - 10
of 150
pro vyhledávání: '"R, Chizzonite"'
Publikováno v:
The Journal of Immunology. 155:4347-4354
Mice with the severe combined immunodeficiency (SCID) possess an IFN-gamma-dependent mechanism of resistance to the intracellular pathogens Toxoplasma gondii and Listeria monocytogenes that is dependent on IL-12-induced production of IFN-gamma by NK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc553de958cb48fd511f524dfc18d9f9
https://doi.org/10.4049/jimmunol.155.9.4347
https://doi.org/10.4049/jimmunol.155.9.4347
Publikováno v:
Blood. 84:125-132
Interleukin-1 (IL-1) has been shown to stimulate hematopoietic progenitor cell growth both in vitro and in vivo. Although IL-1 alone lacks the ability to promote hematopoietic progenitor growth in vitro, it is a potent synergistic factor in combinati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a4ddf6584b644d482ae2d22a9187c77
https://doi.org/10.1182/blood.v84.1.125.bloodjournal841125
https://doi.org/10.1182/blood.v84.1.125.bloodjournal841125
Publikováno v:
The Journal of Immunology. 150:2341-2345
In the colon-26 (C-26) tumor model, the cytokine IL-6 is an important factor involved in experimental cancer cachexia. Recent in vitro data indicated that IL-1 plays a role in the interaction between host macrophages and C-26 cells that express IL-1R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba074a465cb7a10e248e2b86cea5e124
https://doi.org/10.4049/jimmunol.150.6.2341
https://doi.org/10.4049/jimmunol.150.6.2341
Autor:
K Hestdal, SE Jacobsen, FW Ruscetti, CM Dubois, DL Longo, R Chizzonite, JJ Oppenheim, JR Keller
Publikováno v:
Blood. 80:2486-2494
To determine the mechanism(s) by which interleukin-1 (IL-1) promotes granulopoiesis in vivo, we examined the effect of in vivo administration of IL-1 alpha on colony-stimulating factor (CSF) receptor expression on bone marrow cells (BMCs) and whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::124ab926cde80041b876bdd81f232824
https://doi.org/10.1182/blood.v80.10.2486.bloodjournal80102486
https://doi.org/10.1182/blood.v80.10.2486.bloodjournal80102486
Autor:
Ueli Gubler, Mamoru Kiniwa, Christine Fargeas, R Chizzonite, Maurice K. Gately, Guy Delespesse
Publikováno v:
Journal of Clinical Investigation. 90:262-266
Interleukin-12 is a recently discovered lymphokine displaying an array of in vitro activities suggesting a major role in protective immunity against infectious agents like viruses. This study provides evidence that IL-12 may also be implicated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90766906a1ef356e97c79ba14574e9b
https://doi.org/10.1172/jci115846
https://doi.org/10.1172/jci115846
Publikováno v:
The Journal of Immunology. 148:3117-3124
IL-12 is a 75-kDa heterodimeric cytokine composed of disulfide-bonded 35-kDa and 40-kDa subunits. Included among the biologic activities mediated by IL-12 is induction of proliferation of PHA-activated human PBL. The concentration of IL-12 required t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fea69223d146a87cfec204a375a491c
https://doi.org/10.4049/jimmunol.148.10.3117
https://doi.org/10.4049/jimmunol.148.10.3117
Autor:
R Chizzonite, T Truitt, F J Podlaski, A G Wolitzky, P M Quinn, P Nunes, A S Stern, M K Gately
Publikováno v:
The Journal of Immunology. 147:1548-1556
IL-12, formerly known as cytotoxic lymphocyte maturation factor, is a cytokine that stimulates proliferation of PHA-activated human peripheral blood lymphoblasts and synergizes with low concentrations of IL-2 in the induction of lymphokine-activated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f321a38072b1fef8fec033bc2958b91
https://doi.org/10.4049/jimmunol.147.5.1548
https://doi.org/10.4049/jimmunol.147.5.1548
Autor:
J Hakimi, R Chizzonite, D R Luke, P C Familletti, P Bailon, J A Kondas, R S Pilson, P Lin, D V Weber, C Spence
Publikováno v:
The Journal of Immunology. 147:1352-1359
The anti-Tac mAb has been shown to bind to the p55 chain of the IL-2R, block IL-2 binding and inhibit T cell proliferation. A humanized form of anti-Tac (HAT) has been constructed that retains the binding properties of murine anti-Tac (MAT). These tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dd9b4219e2e04b504dcd2a0a973e463
https://doi.org/10.4049/jimmunol.147.4.1352
https://doi.org/10.4049/jimmunol.147.4.1352
Publikováno v:
The Journal of Experimental Medicine
Studies of radioresistance and radioprotection provide an excellent in vivo model for dissection of the pathophysiological role of cytokines. The availability of neutralizing antibodies to cytokines has made it possible to assess the contribution of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7dec8b9c984d75342bddd788c74390
https://doi.org/10.1084/jem.173.5.1177
https://doi.org/10.1084/jem.173.5.1177
Publikováno v:
Blood. 76:57-62
Interleukin-1 (IL-1) is radioprotective and induces both circulating colony-stimulating factor(s) (CSF) and IL-6 in mice. We evaluated the relationship among these three responses to IL-1 using anti-IL-1 receptor antibody 35F5. This antibody in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20ec622d9d8c9b0cf28d754fcd9b125
https://doi.org/10.1182/blood.v76.1.57.57
https://doi.org/10.1182/blood.v76.1.57.57