Zobrazeno 1 - 10
of 554
pro vyhledávání: '"R, Breese"'
Autor:
Kathryn M. Harper, Darin J. Knapp, Caroline A. Todd, Irina Balan, Laure Aurelian, Hugh E. Criswell, George R. Breese
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Chemokines such as chemokine (C-C motif) ligand 2 (CCL2) play a role in several behaviors, including anxiety-like behavior, but whether neurons are an important source of CCL2 for behavior and how neuronal CCL2 may work to affect behavior are still d
Externí odkaz:
https://doaj.org/article/bd0e8ceac01045ddae6df7b3817fe7e3
Autor:
Jacob Pfeil, Lauren M Sanders, Ioannis Anastopoulos, A Geoffrey Lyle, Alana S Weinstein, Yuanqing Xue, Andrew Blair, Holly C Beale, Alex Lee, Stanley G Leung, Phuong T Dinh, Avanthi Tayi Shah, Marcus R Breese, W Patrick Devine, Isabel Bjork, Sofie R Salama, E Alejandro Sweet-Cordero, David Haussler, Olena Morozova Vaske
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007753 (2020)
Precision oncology has primarily relied on coding mutations as biomarkers of response to therapies. While transcriptome analysis can provide valuable information, incorporation into workflows has been difficult. For example, the relative rather than
Externí odkaz:
https://doaj.org/article/6b18e66d017444afb3146ec81d8a8f6f
Autor:
Shruti Menon, Marcus R. Breese, Yone Phar Lin, Hannah Allegakoen, Shruthi Perati, Ann Heslin, Max A. Horlbeck, Jonathan Weissman, E. Alejandro Sweet-Cordero, Trever G. Bivona, Asmin Tulpule
While oncogenes promote cancer cell growth, unrestrained proliferation represents a significant stressor to cellular homeostasis networks such as the DNA damage response (DDR). To enable oncogene tolerance, many cancers disable tumor suppressive DDR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aebbf27fb4ff7deea6627704a054eeb0
https://doi.org/10.1101/2023.04.30.538578
https://doi.org/10.1101/2023.04.30.538578
Autor:
Courtney R. Schott, Amanda L. Koehne, Leanne C. Sayles, Elizabeth P. Young, Cuyler Luck, Katharine Yu, Alex G. Lee, Marcus R. Breese, Stanley G. Leung, Hang Xu, Avanthi Tayi Shah, Heng-Yi Liu, Aviv Spillinger, Inge H. Behroozfard, Kieren D. Marini, Phuong T. Dinh, María V. Pons Ventura, Emma N. Vanderboon, Florette K. Hazard, Soo-Jin Cho, Raffi S. Avedian, David G. Mohler, Melissa Zimel, Rosanna Wustrack, Christina Curtis, Marina Sirota, E. Alejandro Sweet-Cordero
Publikováno v:
bioRxiv
Models to study metastatic disease in rare cancers are needed to advance preclinical therapeutics and to gain insight into disease biology, especially for highly aggressive cancers with a propensity for metastatic spread. Osteosarcoma is a rare cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0ee0ac364e1000526423f6f55b43f81
https://doi.org/10.1101/2023.01.19.524562
https://doi.org/10.1101/2023.01.19.524562
Publikováno v:
Journal of Virus Eradication, Vol 3, Iss , Pp 29- (2017)
Externí odkaz:
https://doaj.org/article/30f5224d4cf348bc8d1bc79786e30352
Autor:
Henry J. Martell, Avanthi T. Shah, Alex G. Lee, Bogdan Tanasa, Stanley G. Leung, Aviv Spillinger, Heng-Yi Liu, Inge Behroozfard, Phuong Dinh, María V. Pons Ventura, Florette K. Hazard, Arun Rangaswami, Sheri L. Spunt, Norman J. Lacayo, Tabitha Cooney, Jennifer G. Michlitsch, Anurag K. Agrawal, Marcus R. Breese, Alejandro Sweet-Cordero
Publikováno v:
Cancer Research. 83:1509-1509
For many pediatric cancer patients, commonly used gene-panel sequencing tests yield few actionable results, partly due to the complex genomic alterations present. We hypothesized that an unbiased approach, combining whole-genome (WGS) and RNA sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27b898ddfe3bc343e773f0ae5f6196c3
https://doi.org/10.1158/1538-7445.am2023-1509
https://doi.org/10.1158/1538-7445.am2023-1509
Autor:
Andrew S. Clugston, Megan Ostrowski, Coco Wu, Leanne Sayles, Stanley G. Leung, Vijay Ramani, E. Alejandro Sweet-Cordero, Marcus R. Breese
Publikováno v:
Cancer Research. 83:214-214
We have leveraged long-read and spatial sequencing modalities to identify patient-specific oncogenic alterations for treatment of pediatric osteosarcomas. Osteosarcoma (OS) is the most common primary bone malignancy in children and young adults, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dc2faed665200d18d19116842ad15ef
https://doi.org/10.1158/1538-7445.am2023-214
https://doi.org/10.1158/1538-7445.am2023-214
Autor:
Anya Levinson, Jessica Van Ziffle, M Dwight Chen, Jacob Pfeil, Inge Behroozfard, E. Alejandro Sweet-Cordero, Charles Zaloudek, Avanthi Tayi Shah, Stanley G. Leung, Elliot Stieglitz, Arjun A. Rao, Benjamin Laguna, Nicholas R. Ladwig, Henry J Martell, Sofie R. Salama, Alex G. Lee, Marcus R. Breese, Lee-may Chen
Publikováno v:
JCO Precision Oncology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda6e5cb23a53fecc0fc172016633116
https://doi.org/10.1200/po.20.00132
https://doi.org/10.1200/po.20.00132
Autor:
Nayana Wijayawardhane, Brian C. Shonesy, Thirumalini Vaithianathan, Noemi Pandiella, Julia Vaglenova, Charles R. Breese, Alexander Dityatev, Vishnu Suppiramaniam
Publikováno v:
Neurobiology of Disease, Vol 29, Iss 1, Pp 81-91 (2008)
Ethanol-induced damage in the developing hippocampus may result in cognitive deficits such as those observed in fetal alcohol spectrum disorder (FASD). Cognitive deficits in FASD are partially mediated by alterations in glutamatergic synaptic transmi
Externí odkaz:
https://doaj.org/article/a3b18452f4f043c9a9b852d52fe74158
Autor:
Stanley G. Leung, Avanthi Tayi Shah, Ash A. Alizadeh, Heike E. Daldrup-Link, Inge Behroozfard, Allison Pribnow, Jacob J. Chabon, Florette K. Hazard, David M. Kurtz, Tej D. Azad, Marcus R. Breese, Norman J. Lacayo, Soo-Jin Cho, E. Alejandro Sweet-Cordero, Sheri L. Spunt, Maximilian Diehn, Kieuhoa T. Vo, Frederick M. Wittber, Arun Rangaswami, Heng-Yi Liu, Aviv Spillinger, Krystal Straessler, Emily G. Hamilton
Publikováno v:
Molecular cancer therapeutics, vol 20, iss 10
Mol Cancer Ther
Mol Cancer Ther
Most circulating tumor DNA (ctDNA) assays are designed to detect recurrent mutations. Pediatric sarcomas share few recurrent mutations but rather are characterized by translocations and copy-number changes. We applied Cancer Personalized Profiling by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb53f86840895e7d172afc93a12b111
https://escholarship.org/uc/item/4zr836sf
https://escholarship.org/uc/item/4zr836sf