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Effect of Vupanorsen on Non-High-Density Lipoprotein Cholesterol Levels in Statin-Treated Patients With Elevated Cholesterol: TRANSLATE-TIMI 70

Autor: Brian A. Bergmark, Nicholas A. Marston, Candace R. Bramson, Madelyn Curto, Vesper Ramos, Alexandra Jevne, Julia F. Kuder, Jeong-Gun Park, Sabina A. Murphy, Subodh Verma, Wojtek Wojakowski, Steven G. Terra, Marc S. Sabatine, Stephen D. Wiviott, Diane Carbonneau, Raphael Poulin-Robitaille, Jeffrey Wayne, Keung Lee, Samuel Mujica Trenche, Petros Dzongowski, Daniel Gaudet, Joanna Van, Dilawar Ajani, Harold Bays, John O’Mahony, Adam Janas, John Scott, Moustafa Ashraf Moustafa, Thomas Ransom, Sabrina Benjamin, Naresh Aggarwal, Pawel Bogdanski, Douglas Friars, Robert Schlosser, Boguslaw Okopien, Madhusudan Budhraja, Lawrence Feld, Leslie Klaff, Guy Tellier, Giuseppe Mazza, Iwona Wierzbicka, Ewa Jazwinska-Tarnawska, Fernando Boccalandro, Julio Rosenstock, Elizabeth Marquez, Kim Barbel-Johnson, Katarzyna Madziarska, Kenneth Heaton, Jean-Claude Tardif, John Rubino, Miguel Trevino, Katie Moriarty, Anil Gupta, Wojciech Wojakowski, James Fidelholtz, Dinesh Gupta, Hani Alasaad, Shane Christensen, Parag Shah, Stephanie Li, Mark Sherman, Andre Frechette, Cecilia Arango, Alan Egan, Sunny Srivastava, Archna Bajaj, Carlos Ince Jr, Aleksander Zurakowski

Publikováno v: Circulation. 145(18)

Background: Genetic loss-of-function variants in ANGPTL3 are associated with lower levels of plasma lipids. Vupanorsen is a hepatically targeted antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Methods: Adults

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12a6c0c8169d6edb06e1e63884560053
https://pubmed.ncbi.nlm.nih.gov/35449408

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Lack of a pharmacokinetic interaction between azithromycin and chloroquine

Autor: Jack A, Cook, Edward J, Randinitis, Candace R, Bramson, David L, Wesche

Publikováno v: The American journal of tropical medicine and hygiene. 74(3)

A study was conducted to investigate a possible pharmacokinetic interaction between azithromycin and chloroquine. Twenty-four subjects received azithromycin, 1,000 mg a day for three days, followed by a washout period, then azithromycin, 1,000 mg plu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::94680854c620b97fa9f80d95ac61ce6f
https://pubmed.ncbi.nlm.nih.gov/16525098

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Psychometric evaluation of the Beck Depression Inventory-II with primary care medical patients

Autor: R C, Arnau, M W, Meagher, M P, Norris, R, Bramson

Publikováno v: Health psychology : official journal of the Division of Health Psychology, American Psychological Association. 20(2)

This study evaluated the psychometric characteristics of the Beck Depression Inventory-II (BDI-II; A. T. Beck, R. A. Steer,G. K. Brown, 1996) in a primary care medical setting. A principal-components analysis with Promax rotation indicated the presen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc563d2e5d62605770400d9b28a4031c
https://pubmed.ncbi.nlm.nih.gov/11315728

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Preconsultation education promoting breast cancer screening: does the choice of media make a difference?

Autor: R L, Street, A, Van Order, R, Bramson, T, Manning

Publikováno v: Journal of cancer education : the official journal of the American Association for Cancer Education. 13(3)

Multimedia technology can be a valuable resource for health promotion and patient education initiatives because it allows messages to be presented within an environment that is both sensory-rich and interactive (i.e., the user can explore the informa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::494ea81e2479ae52a8581816723944b1
https://pubmed.ncbi.nlm.nih.gov/10898560

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Occult vascular injuries following gunshot wounds resulting in long bone fractures of the extremities

Autor: J, Norman, V, Gahtan, M, Franz, R, Bramson

Publikováno v: The American surgeon. 61(2)

The routine use of arteriography following penetrating injuries to the extremities has declined in popularity in recent years. A careful physical examination coupled with Doppler-derived blood pressure has been shown to be sufficient to determine the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c3931c8130b6317ad9422a905af4b1d4
https://pubmed.ncbi.nlm.nih.gov/7856975

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A 2.0-A structure of the blue copper protein (cupredoxin) from Alcaligenes faecalis S-6

Autor: E T, Adman, S, Turley, R, Bramson, K, Petratos, D, Banner, D, Tsernoglou, T, Beppu, H, Watanabe

Publikováno v: The Journal of biological chemistry. 264(1)

The structure of a blue copper protein, cupredoxin, from the potent denitrifying bacterium Alcaligenes faecalis S-6, has been determined and refined against 2 A x-ray diffraction data. The agreement between observed and calculated structure factors i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::dda87ec78cbf591c39cb4cbc982b398d
https://pubmed.ncbi.nlm.nih.gov/2909547

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