Global adaptation complicates the interpretation of genome scans for local adaptation

Autor: Tom R. Booker, Sam Yeaman, Michael C. Whitlock

Publikováno v: Evolution Letters, Vol 5, Iss 1, Pp 4-15 (2021)

Abstract Spatially varying selection promotes variance in allele frequencies, increasing genetic differentiation between the demes of a metapopulation. For that reason, outliers in the genome‐wide distribution of summary statistics measuring geneti

Externí odkaz: https://doaj.org/article/091676c3ea494c1d8a242006c207d094

Inferring Parameters of the Distribution of Fitness Effects of New Mutations When Beneficial Mutations Are Strongly Advantageous and Rare

Autor: Tom R. Booker

Publikováno v: G3: Genes, Genomes, Genetics, Vol 10, Iss 7, Pp 2317-2326 (2020)

Characterizing the distribution of fitness effects (DFE) for new mutations is central in evolutionary genetics. Analysis of molecular data under the McDonald-Kreitman test has suggested that adaptive substitutions make a substantial contribution to b

Externí odkaz: https://doaj.org/article/daeb102b1206406e88be4cdad59554cc

Genetic diversity loss in the Anthropocene

Autor: Moises Exposito-Alonso, Tom R. Booker, Lucas Czech, Lauren Gillespie, Shannon Hateley, Christopher C. Kyriazis, Patricia L. M. Lang, Laura Leventhal, David Nogues-Bravo, Veronica Pagowski, Megan Ruffley, Jeffrey P. Spence, Sebastian E. Toro Arana, Clemens L. Weiß, Erin Zess

Publikováno v: Exposito-Alonso, M, Booker, T R, Czech, L, Gillespie, L, Hateley, S, Kyriazis, C C, Lang, P L M, Leventhal, L, Nogues-Bravo, D, Pagowski, V, Ruffley, M, Spence, J P, Arana, S E T, Weiss, C L & Zess, E 2022, ' Genetic diversity loss in the Anthropocene ', Science, vol. 377, no. 6613, pp. 1431-1435 . https://doi.org/10.1126/science.abn5642

More species than ever before are at risk of extinction due to anthropogenic habitat loss and climate change. But even species that are not threatened have seen reductions in their populations and geographic ranges, likely impacting their genetic div

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae8eff7173233e7a386a03084dab0523
https://doi.org/10.1126/science.abn5642

How useful is genomic data for predicting maladaptation to future climate?

Autor: Brandon M. Lind, Rafael Candido-Ribeiro, Pooja Singh, Mengmeng Lu, Dragana Obreht Vidakovic, Tom R. Booker, Michael C. Whitlock, Sam Yeaman, Nathalie Isabel, Sally N. Aitken

Methods using genomic information to forecast population maladaptation to climate change are becoming increasingly common, yet the lack of model validation poses serious hurdles toward their incorporation into management and policy. Here, we compare

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fac2667aa8c4f2ba832f4f54936c6a49
https://doi.org/10.1101/2023.02.10.528022

Disentangling the genetic consequences of demographic change

Autor: Julia M. Kreiner, Tom R. Booker

Publikováno v: Molecular ecologyREFERENCES.

Quantifying the impact of human activity on the capacity of populations to persist is paramount to conservation biology, as numerous species and populations have already been driven to or beyond the brink of extinction. Those populations that persist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175cee790cb5d5d15052325a1773f597
https://pubmed.ncbi.nlm.nih.gov/36440474