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Autor:
Michel Kraemer, Dominique Briane, J.-C. Kouyoumdjian, J.-L. Moretti, Anna Starzec, R. Beaupain, Olivier Oudar
Publikováno v:
Biology of the Cell. 95:257-264
Genetic and cellular heterogeneity is one of mechanisms involved in increasing tumour aggressiveness during neoplastic progression. Development of drug-resistant tumour cell subpopulations is a major problem in clinical oncology. Multi-drug resistant
Publikováno v:
Tumor Biology. 18:135-145
Lymphokine-activated killer (LAK) cells were cocultured in the presence of interleukin-2 (IL-2), with pulmonary surfactant secreting A549 lung carcinoma nodules and maintained in continuous three-dimensional culture for 2-6 days in an attempt to test
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 29:100-104
Publikováno v:
Fibrinolysis. 4:61-66
Summary The effects of TNF have been studied on the fibrinolytic activity of A549 lung carcinoma cells in an attempt to provide information on the effect of this factor on the fibrinolytic balance in the microenvironment of tumour cells. The results
EFFECTS OF LYMPHOKINE-ACTIVATED KILLER-CELLS ON MELANOMA NODULES MAINTAINED IN 3-DIMENSIONAL CULTURE
Publikováno v:
International Journal of Oncology.
Lymphokine activated killer (LAK) cells were cocultivated from 2 to 6 days with WM266 metastatic melanoma cells maintained as nodules in organotypic culture. The LAK cells in suspension were allowed to deposit freely on the nodule surface from where
Publikováno v:
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 15(2)
In order to better understand the interaction between activated lymphocytes and breast carcinoma cells, we studied the degree of infiltration, the membrane contacts established and their cytostatic and cytolytic effects in MCF-7 nodules maintained in
Publikováno v:
In vitro cellulardevelopmental biology. Animal. (12)
Publikováno v:
In vivo (Athens, Greece). 6(6)
The antiproliferative and cytodifferentiating effects of a new stable butyric derivative, monobut-3, were compared using human MDA-MB-231 breast cancer cells grown in three dimension as either in vitro tumor nodules or in vivo xenograft tumors. In in