Zobrazeno 1 - 10
of 132
pro vyhledávání: '"R, Baurain"'
Publikováno v:
Clinical and Experimental Metastasis. 16:193-203
We used Transwell chambers to study separately cellular motility and invasion. In order to assess the cellular motility, polycarbonate microporous filters were coated with extracellular matrix proteins which adsorbed on the filters without clogging t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c54ebed287c17755b5a4865c128bbcfd
https://doi.org/10.1023/a:1006532523152
https://doi.org/10.1023/a:1006532523152
Autor:
O. van Tellingen, W.J. Nooyen, R. Baurain, H.R. van der Woude, W.W. ten Bokkel Huinink, J. H. Beijnen
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 574:293-298
The determination of N-(deacetyl-O-4-vinblastoyl-23)- l -tryptophan (vintriptol acid, VtrpA), a metabolite of the investigational semi-synthetic vinca alkaloid vintriptol [N-(deacetyl-O-4-vinblastoyl-23)- l -ethyltryptophan, VtrpE], in plasma and uri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302ab7a4a7f97cf6490946a48a9d0e9f
https://doi.org/10.1016/0378-4347(92)80042-o
https://doi.org/10.1016/0378-4347(92)80042-o
Autor:
A, Trouet, A, Passioukov, K, Van derpoorten, A M, Fernandez, J, Abarca-Quinones, R, Baurain, T J, Lobl, C, Oliyai, D, Shochat, V, Dubois
Publikováno v:
Cancer research. 61(7)
Oligopeptidic derivatives of anthracyclines unable to penetrate cells were prepared and screened for their stability in human blood and their reactivation by peptidases secreted by cancer cells. N-beta-alanyl-L-leucyl-L-alanyl-L-leucyl-doxorubicin wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f82800632e6c0607bfcceeab1b14272f
https://pubmed.ncbi.nlm.nih.gov/11306455
https://pubmed.ncbi.nlm.nih.gov/11306455
Publikováno v:
Clinicalexperimental metastasis. 16(2)
We used Transwell chambers to study separately cellular motility and invasion. In order to assess the cellular motility, polycarbonate microporous filters were coated with extracellular matrix proteins which adsorbed on the filters without clogging t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05048654245f3e24d6bf628fb06c3592
https://pubmed.ncbi.nlm.nih.gov/9514101
https://pubmed.ncbi.nlm.nih.gov/9514101
Autor:
R. Baurain, J. H. Beijnen, H.R. van der Woude, W.J. Nooyen, O. van Tellingen, W.W. ten Bokkel Huinink
Publikováno v:
Journal of chromatography. 553(1-2)
Procedures for the determination of vinblastine (VBL), 4-O-deacetylvinblastine (DVBL) and 4-O-deacetylvinblastine-3-oic acid (DVBLA) in biological samples using high-performance liquid chromatography (HPLC) combined with selective sample clean-up are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc9507450375cffa47d5fab472ece62
https://pubmed.ncbi.nlm.nih.gov/1787167
https://pubmed.ncbi.nlm.nih.gov/1787167
Publikováno v:
Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53d34045695cb459a82843659516ab20
https://pubmed.ncbi.nlm.nih.gov/1805716
https://pubmed.ncbi.nlm.nih.gov/1805716
Publikováno v:
Archives of Toxicology ISBN: 9783540514220
The primary task of industrial toxicologists is to provide a comprehensive assessment of the adverse effects of selected chemical substances in several animal species and over a broad range of doses. Increasingly, their collaboration is also required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bb3c1c7e5ed346f90f6be073f28cde6
https://doi.org/10.1007/978-3-642-74936-0_22
https://doi.org/10.1007/978-3-642-74936-0_22
Autor:
O. van Tellingen, W.W. ten Bokkel Huinink, H.R. van der Woude, R. Baurain, J. H. Beijnen, W.J. Nooyen
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 8(8-12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9b6d80a3f1d7d699a64634c45db1938
https://pubmed.ncbi.nlm.nih.gov/2100581
https://pubmed.ncbi.nlm.nih.gov/2100581
Publikováno v:
Journal of Medicinal Chemistry. 23:1171-1174
The accumulation of amino acid and dipeptide derivatives of DNR has been studied in vitro on L1210 cells. Only Leu-DNR reaches accumulation levels close to DNR, while Val-DNR, Ile-DNR, and Leu-Leu-DNR reach intermediate values. Intracellular DNR was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::973f9b865f2d7fc01f6d3def08f4e0c2
https://doi.org/10.1021/jm00185a004
https://doi.org/10.1021/jm00185a004
Publikováno v:
Cancer Chemotherapy and Pharmacology. 9:93-96
When injected rapidly IV into rabbits, the plasma levels of free DOX decreased biphasically and the drug was distributed in a volume greater than the body volume. When given as a DNA complex, the area under the concentration versus time curve was inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609f0abbcdf6bd9eb45f28ce9caf8ab3
https://doi.org/10.1007/bf00265386
https://doi.org/10.1007/bf00265386