Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R, Barsden"'
Autor:
Bettina C. Schock, B Malcomson, S Cheung, Catriona Kelly, Burkhard Hirsch, Agnieszka Czerwiec, Joseph Elborn, R. Barsden, H Dürkop, Madeleine Ennis, James Reihill, A. Bertelsen
Publikováno v:
British Journal of Pharmacology. 173:778-789
Background and Purpose NF-κB-driven inflammation is negatively regulated by the zinc finger protein A20. Gibberellic acid (GA3) is a plant-derived diterpenoid with documented anti-inflammatory activity, which is reported to induce A20-like zinc fing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a80d413c3560635a6183bae841e3cebc
https://doi.org/10.1111/bph.13200
https://doi.org/10.1111/bph.13200
Autor:
Shauna Donegan, Beth Malcomson, Amal El Banna, Shu-Dong Zhang, Gayathri Thillaiyampalam, Joseph Elborn, Bettina C. Schock, Madeleine Ennis, Hollie Wilson, Eleonora Veglia, Catriona Kelly, R. Barsden
Publikováno v:
Malcomson, B, Wilson, H, Thillaiyampalan, G, Barsden, R, Donegan, S, El Banna, A, Elborn, J, Ennis, M, Kelly, C, Zhang, S-D & Schock, B 2016, ' Connectivity Mapping (ssCMap) To Predict A20 Inducing Drugs: Anti-inflammatory Action In Cystic Fibrosis ', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 26, pp. E3725–E3734 . https://doi.org/10.1073/pnas.1520289113
Cystic fibrosis (CF) lung disease is characterized by chronic and exaggerated inflammation in the airways. Despite recent developments to therapeutically overcome the underlying functional defect in the cystic fibrosis transmembrane conductance regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a704e540c6e2d7070e0d36dbcf7c779a
https://doi.org/10.1073/pnas.1520289113
https://doi.org/10.1073/pnas.1520289113
Autor:
J A, Reihill, B, Malcomson, A, Bertelsen, S, Cheung, A, Czerwiec, R, Barsden, J S, Elborn, H, Dürkop, B, Hirsch, M, Ennis, C, Kelly, B C, Schock
Publikováno v:
British journal of pharmacology. 173(4)
NF-κB-driven inflammation is negatively regulated by the zinc finger protein A20. Gibberellic acid (GA3 ) is a plant-derived diterpenoid with documented anti-inflammatory activity, which is reported to induce A20-like zinc finger proteins in plants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78495a79e888cc0614148a09c9444539
https://pubmed.ncbi.nlm.nih.gov/26013851
https://pubmed.ncbi.nlm.nih.gov/26013851
Publikováno v:
Journal of Cystic Fibrosis. 13:S74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14d6caa549d8426d90fb16d27f1319f
https://doi.org/10.1016/s1569-1993(14)60246-0
https://doi.org/10.1016/s1569-1993(14)60246-0
Akademický článek
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Akademický článek
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Publikováno v:
Journal of Cystic Fibrosis. :S75
Objectives: Inflammatory signalling − driven by activation of NF-uB − is negatively regulated by the zinc finger protein A20. In CF A20 expression/function is significantly reduced and the lack of A20 is associated with reduced lung function (Kel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664f4ad54c134d8705498c1e96b1f0d1