Zobrazeno 1 - 10
of 1 139
pro vyhledávání: '"R, BASERGA"'
Autor:
R. Baserga
From a logical point of view, cell division is regulated by the environment and by the ability of the cell to respond to the environmental signals. The terminology of the cell cycle, the elaborate mathematical models, and the kinetic analyses are all
Autor:
R Baserga, S Alatalo, Serdar Yilmaz, P Aho, G Cozzone, Marjukka Myllärniemi, B A Jameson, Einari Aavik, Anne Räisänen-Sokolowski, Pekka Häyry
Publikováno v:
The FASEB Journal. 9:1336-1344
Restenosis after angioplasty is believed to result from stimulation of smooth muscle cells (SMC) by various growth-promoting factors as a consequence of endothelial injury. In this study we have tested the hypothesis that insulin-like growth factor-1
Autor:
R, Baserga
Publikováno v:
The American journal of pathology. 137(3)
Autor:
R Baserga
Publikováno v:
Journal of Cell Science. 98:433-436
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(7)
The type 1 insulin-like growth factor receptor (IGF-IR) is emerging as a powerful survival factor against a variety of apoptotic agents in many cell types. A mutant IGF-IR designated 486/STOP is known to induce apoptosis and inhibit the growth of hum
Autor:
R, Baffa, K, Reiss, E A, El-Gabry, J, Sedor, M L, Moy, D, Shupp-Byrne, S E, Strup, W W, Hauck, R, Baserga, L G, Gomella
Publikováno v:
Techniques in urology. 6(3)
Insulin-like growth factor 1 (IGF-1) is an important mitogenic and antiapoptotic peptide that affects the proliferation of normal and malignant cells. Contradictory reports on the association between serum IGF-1 level and prostate cancer have been hi
Publikováno v:
Cancer research. 60(15)
R- cells are 3T3 cells derived from mouse embryos with a targeted disruption of the type 1 insulin-like growth factor receptor (IGF-IR) genes. R- cells are refractory to transformation by a variety of viral and cellular oncogenes, including an activa
Autor:
A, Morrione, G, Romano, M, Navarro, K, Reiss, B, Valentinis, M, Dews, E, Eves, M R, Rosner, R, Baserga
Publikováno v:
Cancer research. 60(8)
The type I insulin-like growth factor receptor (IGF-IR) is known to send two seemingly contradictory signals inducing either cell proliferation or cell differentiation, depending on cell type and/or conditions. H19-7 cells are rat hippocampal neurona
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(11)
The insulin-like growth factor I receptor is known to play a major role in transformation and apoptosis. The dominant negative mutant of the insulin-like growth factor I receptor, designated 486/STOP, causes massive apoptosis of tumor cells and inhib
Publikováno v:
Developments in biological standardization. 94
We have evaluated the effect of antisense IGF receptor transcripts on the proliferation and tumorigenicity in an SV40-induced, immunocompetent hamster mesothelioma model (H9A). Expression of IGF-1 and IGF-1 receptor (IGF-1 R) genes was identified fro