Zobrazeno 1 - 10 of 370 pro vyhledávání: '"R, Asofsky"'
2
Induction of differentiation in a B lymphoma X B lymphocyte hybrid line. II. Intraclonal heterogeneity in growth, secretion of IgM, and cytokine production in response to lipopolysaccharide
Autor: J Little, D W Alling, R Asofsky
Publikováno v: The Journal of Immunology. 150:2129-2138
Murine B lymphocyte clones have proven to be useful models to study aspects of B lymphocyte growth and development. It had been previously shown that induction of TH2.2 (B lymphoma X B lymphocyte) with LPS resulted in differentiation into IgM-secreti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5c89c164e707146e99e7a6ad1c51b0c
https://doi.org/10.4049/jimmunol.150.6.2129
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3
Functional studies on B cell hybridomas with B cell surface antigens. I. Effects of anti-immunoglobulin antibodies on proliferation and differentiation
Autor: T Hamano, R Asofsky
Publikováno v: The Journal of Immunology. 130:2027-2032
B cell hybridomas with Ia and IgM molecules on the cell membrane were treated with either purified goat anti-mouse mu antibody (anti-mu) or monoclonal rat anti-mouse IgM antibody (anti-IgM). The spontaneous uptake of [3H] thymidine by these cells was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2402d21abc35349fa993563199cf2a6f
https://doi.org/10.4049/jimmunol.130.5.2027
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4
High anti-TNP plaque-forming cell potential of residual mIg+ cells in a T cell population
Autor: J J Mond, M G Mage, T L Rothstein, D E Mosier, H Herrod, R Asofsky, W E Paul
Publikováno v: The Journal of Immunology. 125:1526-1529
In the course of experiments designed to study the immune response of purified populations of B lymphocytes to thymus-independent (TI) antigens, a variety of cell purification procedures were followed. In using anti-immunoglobulin-coated dishes to se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4d4b4081813143328b25bb671329e7c
https://doi.org/10.4049/jimmunol.125.4.1526
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5
Suppression of spontaneous reticulum cell sarcoma development and of syngeneic stimulator cell by anti-mu treatment of SJL/J mice
Autor: I R Katz, R Asofsky, G J Thorbecke
Publikováno v: The Journal of Immunology. 125:1355-1359
The cellular origin of reticulum cell sarcoma (RCS) in SJL/J mice was studied by comparing the incidence of spontaneous RCS in control mice and in mice suppressed with goat anti-mu Ig from birth on. At 10 months of age anti-mu suppressed mice had 0%
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::72aec07add9db32b0311d0ee789b913c
https://doi.org/10.4049/jimmunol.125.3.1355
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6
IA mutant functional antigen-presenting cell lines
Autor: L H Glimcher, T Hamano, R Asofsky, D H Sachs, M Pierres, L E Samelson, S O Sharrow, W E Paul
Publikováno v: The Journal of Immunology. 130:2287-2294
We describe a protocol for the selection of mutant cells with an altered pattern of Ia antigenic determinants and antigen-presenting properties from a homogeneous population of functional antigen-presenting cells (APC). The APC line used in this work
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33a6abbd60ed961f9437f71fe7b1c0a3
https://doi.org/10.4049/jimmunol.130.5.2287
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7
Effects of deoxycoformycin in mice. II. Differences between the drug sensitivities and purine metabolizing enzymes of transplantable lymphomas of varying immunologic phenotypes
Autor: H Ratech, J Kim, R Asofsky, G J Thorbecke, R Hirschhorn
Publikováno v: The Journal of Immunology. 132:3077-3084
Transplantable BALB/c and AKR lymphomas of different cell surface immunologic phenotypes have distinctive patterns of response to the ADA inhibitor DCF in vivo and in vitro. BAL 9, a lymphoma of the Lyt-1+,2+ T cell phenotype, was the most sensitive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd585e2ecf4f5bc9ed8df7f6c1844d59
https://doi.org/10.4049/jimmunol.132.6.3077
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9
Radioimmunoassay for detecting antibodies against murine malarial parasite antigens: monoclonal antibodies recognizing Plasmodium yoelii antigens
Autor: K J Kim, D W Taylor, C B Evans, R Asofsky
Publikováno v: The Journal of Immunology. 125:2565-2569
A solid-phase radioimmunoassay (SPRIA) in microtiter wells was established for detecting antibodies against Plasmodium yoelii Ag. The SPRIA was found 1) to require as little as 5 micrograms of crude parasite Ag per well, 2) to be able to detect 0.5 n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f4646c32d87ddf674ce081d74381fe45
https://doi.org/10.4049/jimmunol.125.6.2565
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10
Regulation of anti-hapten antibody responses in vivo: memory, carrier-specific Lyt-2+ T cells can terminate antibody production without altering the peak of response
Autor: C Kanellopoulos-Langevin, B J Mathieson, A Perkins, A Maynard, R Asofsky
Publikováno v: The Journal of Immunology. 132:1639-1646
By using the classical hapten-carrier antigenic system (dinitrophenyl-keyhole limpet hemocyanin) (DNP-KLH), and positive immunoselective techniques for purification of lymphocyte subsets, we studied the kinetics and role of KLH-primed T cells in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::feef1d3f03ba9131f7c96ef6cd8bda3b
https://doi.org/10.4049/jimmunol.132.4.1639
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