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P046 Vitamin D decreases PDIA3 and prevents the enhanced migration of fibroblasts from stricturing Crohn’s disease

Autor: M D Barrachina, R Alos, L Gisbert-Ferrándiz, Sara Calatayud, S Coll, Jesus Cosin-Roger, Dolores Ortiz-Masiá, C Bauset, F Navarro-Vicente

Publikováno v: Journal of Crohn's and Colitis. 14:S156-S156

Background Fibrosis is a common complication in Crohn’s disease (CD) patients and fibroblasts play an important role in the fibrogenic process. Low vitamin D (VD) levels and a defective VD-signalling pathway have been reported in CD. VD signals thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb40a23f1a09d9f42b87620cee3cd720
https://doi.org/10.1093/ecco-jcc/jjz203.175

P003 C86/CD16 macrophages may act as a source of WNT2b in intestinal tissue from B3 Crohn’s disease patients

Autor: P Salvador, M D Barrachina, D.C. Macias-Ceja, Jesus Cosin-Roger, L Gisbert-Ferrándiz, R Alos, Sara Calatayud, J. Manyé, F Navarro-Vicente, M Rodriguez-Antequera, S Coll, Dolores Ortiz-Masiá

Publikováno v: Journal of Crohn's and Colitis. 13:S087-S088

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bff2a9b9c396bd26afeb4c1453cd9199
https://doi.org/10.1093/ecco-jcc/jjy222.127

P045 Local inflammation modulates vitamin D receptor protein levels in fibroblasts

Autor: P Salvador, D.C. Macias-Ceja, M D Barrachina, L Gisbert-Ferrándiz, Sara Calatayud, R Alos, F Navarro-Vicente, Jesus Cosin-Roger

Publikováno v: Journal of Crohn's and Colitis. 13:S109-S109

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94d7ac42c327790c137cda06fc70c2da
https://doi.org/10.1093/ecco-jcc/jjy222.169

M1 Macrophages Activate Notch Signalling in Epithelial Cells: Relevance in Crohn's Disease

Autor: R Alos, M D Barrachina, Dolores Ortiz-Masiá, Juan V. Esplugues, Carlos Hernández, Joaquín Hinojosa, Sara Calatayud, Jesus Cosin-Roger

Publikováno v: Ortiz-Masiá, María Dolores; Cosín Roger, Jesús; Calatayud Romero, Sara; Hernández, C.; Alós, R.; Hinojosa, J.; Esplugues, Juan Vicente; Barrachina Sancho, María Dolores (2016) M1 Macrophages Activate Notch Signalling in Epithelial Cells: Relevance in Crohn's Disease Journal Of Crohns & Colitis
RODERIC. Repositorio Institucional de la Universitat de Valéncia
instname
JOURNAL OF CROHNS & COLITIS
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
Journal of Crohn's & colitis
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA

Background: The Notch signalling pathway plays an essential role in mucosal regeneration, which constitutes a key goal of Crohn's disease (CD) treatment. Macrophages coordinate tissue repair and several phenotypes have been reported which differ in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33d049faab4c6238184641076ee2b09