Overcoming Barriers in Glioblastoma—Advances in Drug Delivery Strategies

Autor: Esther ter Linden, Erik R. Abels, Thomas S. van Solinge, Jacques Neefjes, Marike L. D. Broekman

Publikováno v: Cells, Vol 13, Iss 12, p 998 (2024)

The world of cancer treatment is evolving rapidly and has improved the prospects of many cancer patients. Yet, there are still many cancers where treatment prospects have not (or hardly) improved. Glioblastoma is the most common malignant primary bra

Externí odkaz: https://doaj.org/article/c72f996ace264630b609f4c3eaab3be2

Glioblastoma hijacks microglial gene expression to support tumor growth

Autor: Sybren L. N. Maas, Erik R. Abels, Lieke L. Van De Haar, Xuan Zhang, Liza Morsett, Srinjoy Sil, Joana Guedes, Pritha Sen, Shilpa Prabhakar, Suzanne E. Hickman, Charles P. Lai, David T. Ting, Xandra O. Breakefield, Marike L. D. Broekman, Joseph El Khoury

Publikováno v: Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)

Abstract Background Glioblastomas are the most common and lethal primary brain tumors. Microglia, the resident immune cells of the brain, survey their environment and respond to pathogens, toxins, and tumors. Glioblastoma cells communicate with micro

Externí odkaz: https://doaj.org/article/b9621698f61b420098d1d9686658007c

Preventing inflammation inhibits biopsy-mediated changes in tumor cell behavior

Autor: Maria Alieva, Andreia S. Margarido, Tamara Wieles, Erik R. Abels, Burcin Colak, Carla Boquetale, Herke Jan Noordmans, Tom J. Snijders, Marike L. Broekman, Jacco van Rheenen

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)

Abstract Although biopsies and tumor resection are prognostically beneficial for glioblastomas (GBM), potential negative effects have also been suggested. Here, using retrospective study of patients and intravital imaging of mice, we identify some of

Externí odkaz: https://doaj.org/article/870adc24b20d4709945c1f69dfd3f0c7

Conceptual design of the AGATA 2π array at LNL

Autor: J.J. Valiente-Dobón, R. Menegazzo, A. Goasduff, D. Agguiaro, P. Aguilera, F. Angelini, M. Balogh, D. Bazzacco, J. Benito, G. Benzoni, N. Bez, M. Bolognesi, S. Bottoni, D. Brugnara, S. Carollo, P. Cocconi, A. Cogo, J. Collado, F.C.L. Crespi, A. Ertoprak, R. Escudeiro, F. Galtarossa, E.R. Gamba, A. Gambalonga, B. Góngora Servín, A. Gottardo, A. Gozzelino, M. Gulmini, Z. Huang, T. Marchi, D. Mengoni, P. Modanese, D.R. Napoli, J. Pellumaj, R.M. Pérez-Vidal, S. Pigliapoco, E. Pilotto, L. Ramina, M. Rampazzo, W. Raniero, M. Rebeschini, K. Rezynkina, D. Rosso, M. Scarcioffolo, D. Scarpa, M. Sedlák, R. Smith, N. Toniolo, F. Veronese, V. Volpe, L. Zago, I. Zanon, G. Zhang, R. Abels, M.L. Allegrini, C. Aufranc, G. Baulieu, C. Belkhiria, M. Benettoni, D. Benini, M. Bentley, M. Biasotto, M. Blaizot, J. Blasco Miquel, C. Boiano, A. Boston, H. Boston, A. Boujrad, P. Bourgault, A. Bracco, S. Brambilla, I. Burrows, F. Camera, S. Capra, A. Capsoni, R. Cash, J.V. Civera, E. Clément, S. Coelli, M. Cordwell, L. Corradi, S. Coudert, G. De Angelis, L. De Ruvo, G. Debras, M. Del Fabbro, J. Diklić, N. Dosme, G. Duchene, B. Duclos, J. Dudouet, J. Eberth, S. Elloumi, C. Everett, S. Fantinel, M. Fillinger, E. Fioretto, C. Fransen, A. Gadea, L. Gibelin, V. González, J. Goupil, C. Görgen, A. Grant, K. Green, J. Ha, T. Hartnett, K. Henseler, H. Hess, R. Hirsch, C. Houarner, J. Jacob, T. Joannem, D.S. Judson, N. Karkour, M. Karolak, M. Kebbiri, J. Kieffer, M. Labiche, X. Lafay, P. Le Jeannic, A. Lefevre, E. Legay, F. Legruel, S. Lenzi, S. Leoni, D. Linget, M. Liptrot, A. López-Martens, A. Lotodé, L. Manara, L. Ménager, T. Mijatović, B. Million, A. Minarello, G. Montagnoli, P. Morrall, I. Mullacrane, J. Nyberg, G. Philippon, M. Polettini, F. Popieul, A. Pullia, F. Recchia, P. Reiter, G. Richardt, M. Rocchini, A. Roger, F. Saillant, E. Sanchis, Md.S.R. Laskar, G. Secci, M.-H. Sigward, J. Simpson, N. Solenne, F. Spee, A.M. Stefanini, O. Stézowski, S. Szilner, N. Templeton, Ch. Theisen, S. Thiel, F. Tomasi, S. Tzvetkov, D. Vigano, E. Viscione, O. Wieland, K. Wimmer, G. Wittwer, M. Zielińska

Publikováno v: Nucl.Instrum.Meth.A
Nucl.Instrum.Meth.A, 2023, 1049, pp.168040. ⟨10.1016/j.nima.2023.168040⟩

International audience; The Advanced GAmma Tracking Array (AGATA) has been installed at Laboratori Nazionali di Legnaro (LNL), Italy. In this installation, AGATA will consist, at the beginning, of 13 AGATA triple clusters (ATCs) with an angular cover

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc2cf553b9fb19ad9ade4939cdce8bf
https://hdl.handle.net/11577/3468370

Histological development and integration of the Zebrafish Weberian apparatus

Autor: Selena S. Richardson, Nathan C. Bird, Jeremy R. Abels

Publikováno v: Developmental Dynamics. 249:998-1017

Background The Weberian apparatus enhances hearing in otophysan fishes, including Zebrafish (Danio rerio). Several studies have examined aspects of morphological development of the Weberian apparatus and hearing ability in Zebrafish. A comprehensive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4383fe120276c4aed5999de5312ff2c6
https://doi.org/10.1002/dvdy.172