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pro vyhledávání: '"Quynh-T Le"'
Autor:
Mary Jo Dorie, Mary S. Kovacs, Edward C. Gabalski, Markus Adam, Quynh-T Le, Daniel A. Bloch, Harlan A. Pinto, David J. Terris, J. Martin Brown
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 1, Iss 5, Pp 461-467 (1999)
Tirapazamine (TPZ) [3-amino -1,2,4-benzotriazine 1,4-dioxide, SR4233, WIN 59075, and Tirazone™] is a novel anticancer drug that is selectively activated by the low oxygen environment in solid tumors. By killing the radioresistant hypoxic cells, TPZ
Externí odkaz:
https://doaj.org/article/7d8e2c0581434f3cbe71db842c248a53
Autor:
Quynh T. Le, Mahta Mirzaeiramin, Sophia S. Jung, Randy B. Stein, Cailin Kuchenbecker, U.S.A. California State Polytechnic University-Pomona, Jae Min Jung
Publikováno v:
Global Fashion Management Conference. 2018:1052-1052
Autor:
Primo N. Lara, Derick H Lau, Paul H. Gumerlock, Zelanna Goldberg, P. C. Mack, David R. Gandara, Quynh T Le
Publikováno v:
Seminars in oncology. 29(1 Suppl 4)
Preclinical models in vitro and in vivo have shown that tumor hypoxia alters the malignant cell phenotype, selecting for p53 mutations, stimulating angiogenesis and metastasis, and markedly reducing the efficacy of both radiotherapy and chemotherapy.