Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Quynh T Phan"'
Autor:
Quynh T Phan, Norma V Solis, Max V Cravener, Marc Swidergall, Jianfeng Lin, Manning Y Huang, Hong Liu, Shakti Singh, Ashraf S Ibrahim, Massimiliano Mazzone, Aaron P Mitchell, Scott G Filler
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011579 (2023)
Fungal invasion of the oral epithelium is central to the pathogenesis of oropharyngeal candidiasis (OPC). Candida albicans invades the oral epithelium by receptor-induced endocytosis but this process is incompletely understood. We found that C. albic
Externí odkaz:
https://doaj.org/article/e8148324a566459f8f1ffa7fd287ef45
Autor:
Quynh T Phan, Norma V Solis, Jianfeng Lin, Marc Swidergall, Shakti Singh, Hong Liu, Donald C Sheppard, Ashraf S Ibrahim, Aaron P Mitchell, Scott G Filler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 7, p e1010681 (2022)
During hematogenously disseminated candidiasis, blood borne fungi must invade the endothelial cells that line the blood vessels to infect the deep tissues. Although Candida albicans, which forms hyphae, readily invades endothelial cells, other medica
Externí odkaz:
https://doaj.org/article/743b5ca3cf9542828ee062ad7674967c
Autor:
Hong Liu, Wenjie Xu, Vincent M Bruno, Quynh T Phan, Norma V Solis, Carol A Woolford, Rachel L Ehrlich, Amol C Shetty, Carrie McCraken, Jianfeng Lin, Michael J Bromley, Aaron P Mitchell, Scott G Filler
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009235 (2021)
To gain a better understanding of the transcriptional response of Aspergillus fumigatus during invasive pulmonary infection, we used a NanoString nCounter to assess the transcript levels of 467 A. fumigatus genes during growth in the lungs of immunos
Externí odkaz:
https://doaj.org/article/947ef2889ffa4ef082053220a5482001
Autor:
Marc Swidergall, Norma V Solis, Nicolas Millet, Manning Y Huang, Jianfeng Lin, Quynh T Phan, Michael D Lazarus, Zeping Wang, Michael R Yeaman, Aaron P Mitchell, Scott G Filler
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009221 (2021)
During oropharyngeal candidiasis (OPC), Candida albicans invades and damages oral epithelial cells, which respond by producing proinflammatory mediators that recruit phagocytes to foci of infection. The ephrin type-A receptor 2 (EphA2) detects β-glu
Externí odkaz:
https://doaj.org/article/395ddc2932ba4cfea5fd7af5f93987eb
Autor:
Jianing N Sun, Norma V Solis, Quynh T Phan, Jashanjot S Bajwa, Helena Kashleva, Angela Thompson, Yaoping Liu, Anna Dongari-Bagtzoglou, Mira Edgerton, Scott G Filler
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001181 (2010)
Candida albicans Ssa1 and Ssa2 are members of the HSP70 family of heat shock proteins that are expressed on the cell surface and function as receptors for antimicrobial peptides such as histatins. We investigated the role of Ssa1 and Ssa2 in mediatin
Externí odkaz:
https://doaj.org/article/ac9894ee30824f00a6fcd382cef88be3
Autor:
Quynh T Phan, Carter L Myers, Yue Fu, Donald C Sheppard, Michael R Yeaman, William H Welch, Ashraf S Ibrahim, John E Edwards, Scott G Filler
Publikováno v:
PLoS Biology, Vol 5, Iss 3, p e64 (2007)
Candida albicans is the most common cause of hematogenously disseminated and oropharyngeal candidiasis. Both of these diseases are characterized by fungal invasion of host cells. Previously, we have found that C. albicans hyphae invade endothelial ce
Externí odkaz:
https://doaj.org/article/7de12b1cc3b141c5b28ce0aacaecaed3
Autor:
Hong Liu, Jianfeng Lin, Quynh T. Phan, Fabrice N. Gravelat, Donald C. Sheppard, Scott G. Filler
Publikováno v:
bioRxiv
During the initiation of invasive aspergillosis, inhaledAspergillus fumigatusconidia are deposited on the epithelial cells lining the bronchi, terminal bronchioles, and alveoli. While the interactions ofA. fumigatuswith bronchial and type II alveolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724a44c33ea1876693a270683ac94f62
https://doi.org/10.1101/2023.04.18.537379
https://doi.org/10.1101/2023.04.18.537379
Autor:
Quynh T. Phan, Norma V. Solis, Max V. Cravener, Marc Swidergall, Jianfeng Lin, Manning Y. Huang, Hong Liu, Shakti Singh, Ashraf S. Ibrahim, Massimiliano Mazzone, Aaron P. Mitchell, Scott G. Filler
Publikováno v:
bioRxiv
SummaryFungal invasion of the oral epithelium is central to the pathogenesis of oropharyngeal candidiasis (OPC).Candida albicansinvades the oral epithelium by receptor-induced endocytosis but this process is incompletely understood. We found thatC. a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b09d2ab4cc98f8f93af6959938907a
https://europepmc.org/articles/PMC9980113/
https://europepmc.org/articles/PMC9980113/
Autor:
Jianfeng Lin, Feng Wang, Scott G. Filler, Sarah L. Gaffen, Shan Li, Michael Eng, Norma V. Solis, Marc Swidergall, Quynh T Phan, Tsui-Fen Chou
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
mBio
mBio, vol 12, iss 6
mBio
mBio, vol 12, iss 6
During oropharyngeal candidiasis, Candida albicans activates the epidermal growth factor receptor (EGFR), which induces oral epithelial cells to endocytose the fungus and synthesize proinflammatory mediators. To elucidate EGFR signaling pathways that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eab10a7d3f29970ee985bb2b0195ef1
https://journals.asm.org/doi/10.1128/mBio.02716-21
https://journals.asm.org/doi/10.1128/mBio.02716-21
Autor:
Marc Swidergall, Ashraf S. Ibrahim, Jianfeng Lin, Shakti Singh, Aaron P. Mitchell, Donald C. Sheppard, Norma V. Solis, Scott G. Filler, Hong Liu, Quynh T. Phan
During hematogenously disseminated candidiasis, blood borne fungi must invade the endothelial cells that line the blood vessels to infect the deep tissues. AlthoughCandida albicans, which forms hyphae, readily invades endothelial cells, other medical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f66179e34c68e7e9df5343e1820b2490
https://doi.org/10.1101/2021.09.18.460925
https://doi.org/10.1101/2021.09.18.460925