Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Quynh Phung"'
Autor:
Carolin M. Lieber, Robert M. Cox, Julien Sourimant, Josef D. Wolf, Kate Juergens, Quynh Phung, Manohar T. Saindane, Meghan K. Smith, Zachary M. Sticher, Alexander A. Kalykhalov, Michael G. Natchus, George R. Painter, Kaori Sakamoto, Alexander L. Greninger, Richard K. Plemper
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Molnupiravir was the first orally available SARS-CoV-2 antiviral approved for outpatient use against SARS-CoV-2, but its efficacy against variants of concern, especially delta, was questioned. Here the authors evaluate molnupiravir against variant of
Externí odkaz:
https://doaj.org/article/4980daa3f2c04201ae020f4e00503ea0
Autor:
Emily Romeis, Nicole A P Lieberman, Barbara Molini, Lauren C Tantalo, Benjamin Chung, Quynh Phung, Carlos Avendaño, Anastassia Vorobieva, Alexander L Greninger, Lorenzo Giacani
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011259 (2023)
BackgroundThe TprK protein of the syphilis agent, Treponema pallidum subsp. pallidum (T. pallidum), undergoes antigenic variation in seven discrete variable (V) regions via non-reciprocal segmental gene conversion. These recombination events transfer
Externí odkaz:
https://doaj.org/article/3637a32b0e5d45cab49823cc0c655e9f
Autor:
Michelle J Lin, Austin M Haynes, Amin Addetia, Nicole A P Lieberman, Quynh Phung, Hong Xie, Tien V Nguyen, Barbara J Molini, Sheila A Lukehart, Lorenzo Giacani, Alexander L Greninger
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009753 (2021)
Immune evasion by Treponema pallidum subspecies pallidum (T. pallidum) has been attributed to antigenic variation of its putative outer-membrane protein TprK. In TprK, amino acid diversity is confined to seven variable (V) regions, and generation of
Externí odkaz:
https://doaj.org/article/93670bd7706c4c12aeb62626826fc333
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009612 (2021)
Despite more than a century of research, genetic manipulation of Treponema pallidum subsp. pallidum (T. pallidum), the causative agent of syphilis, has not been successful. The lack of genetic engineering tools has severely limited understanding of t
Externí odkaz:
https://doaj.org/article/2416de458b6342998c140c10f7ea5636
Autor:
Amin Addetia, Nicole A. P. Lieberman, Quynh Phung, Tien-Ying Hsiang, Hong Xie, Pavitra Roychoudhury, Lasata Shrestha, Michelle A. Loprieno, Meei-Li Huang, Michael Gale, Keith R. Jerome, Alexander L. Greninger
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
SARS-CoV-2, the causative agent of coronavirus disease 2019 (COVID-19), is an RNA virus with a large genome that encodes multiple accessory proteins. While these accessory proteins are not required for growth in vitro
Externí odkaz:
https://doaj.org/article/0e18c7c8b75c48a4980e5cd2d2a78a89
Autor:
Amin Addetia, Michelle J. Lin, Quynh Phung, Hong Xie, Meei-Li Huang, Giulia Ciccarese, Ivano Dal Conte, Marco Cusini, Francesco Drago, Lorenzo Giacani, Alexander L. Greninger
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Immune evasion and disease progression of Treponema pallidum subsp. pallidum are associated with sequence diversity in the hypervariable outer membrane protein TprK. Previous attempts to study variation within TprK have sequenced at depths i
Externí odkaz:
https://doaj.org/article/228d25d164af4f5a84dfd3ae4ebe36dc
Autor:
Samuel S. Minot, Vikas Peddu, Alexander L. Greninger, Keith R. Jerome, Arun K. Nalla, Meei Li Huang, Lasata Shrestha, Pavitra Roychoudhury, Hong Xie, Garrett A. Perchetti, Quynh Phung, Adam Reinhardt, Ryan C. Shean, Shriya B. Reddy
Publikováno v:
Clinical Chemistry
Background More than 2 months separated the initial description of SARS-CoV-2 and discovery of its widespread dissemination in the United States. Despite this lengthy interval, implementation of specific quantitative reverse transcription (qRT)-PCR-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264811ee6b677245d232a8cae1032740
https://doi.org/10.1093/clinchem/hvaa106
https://doi.org/10.1093/clinchem/hvaa106
Autor:
Kwanbyung Chae, Van Tu Nguyen, Sangryun Lee, Thi Quynh Phung, Yumin Sim, Maeng-Je Seong, Sang Woon Lee, Yeong Hwan Ahn, Soonil Lee, Seunghwa Ryu, Ji-Yong Park
Publikováno v:
Applied Surface Science. 605:154736
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::794808d7ee0b676c87cd3bed19b29a69
https://doi.org/10.1016/j.apsusc.2022.154736
https://doi.org/10.1016/j.apsusc.2022.154736
Publikováno v:
J Mol Diagn
Sequencing of plasma cell-free DNA (cfDNA) is a promising milieu for broad-based cancer and infectious disease diagnostics. The performance of cfDNA sequencing for infectious disease diagnostics is chiefly limited by inadequate analytical sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df24556db83201dcf58992606cc991a
https://pubmed.ncbi.nlm.nih.gov/35569878
https://pubmed.ncbi.nlm.nih.gov/35569878
Autor:
Alexander L. Greninger, Hong Xie, Austin M. Haynes, Barbara J. Molini, Tien V. Nguyen, Lorenzo Giacani, Sheila A. Lukehart, Amin Addetia, Quynh Phung, Nicole A P Lieberman, Michelle J. Lin
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009753 (2021)
PLoS Neglected Tropical Diseases, Vol 15, Iss 9, p e0009753 (2021)
Immune evasion by Treponema pallidum subspecies pallidum (T. pallidum) has been attributed to antigenic variation of its putative outer-membrane protein TprK. In TprK, amino acid diversity is confined to seven variable (V) regions, and generation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d63da55eb279ac4b439753efc9f6fa
http://europepmc.org/articles/PMC8480903
http://europepmc.org/articles/PMC8480903