Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Quynh N Vo"'
Publikováno v:
JACS Au, Vol 1, Iss 12, Pp 2208-2215 (2021)
Externí odkaz:
https://doaj.org/article/ccadad67c2ea4d6cb3717ed13f1dd8d9
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Structures of mu-opioid receptor (mOR) in complex with morphine derivatives have been determined; but the structural basis of mOR activation by fentanyl-like synthetic opioids remains unclear. Here, authors use state-of-the-art simulation techniques
Externí odkaz:
https://doaj.org/article/d6525e7321244607a119714580e78d1a
Autor:
Paween Mahinthichaichan, Ruibin Liu, Quynh N. Vo, Christopher R. Ellis, Lidiya Stavitskaya, Jana Shen
Publikováno v:
J Chem Inf Model
The nation’s opioid overdose deaths reached an all-time high in 2021. The majority of deaths are due to synthetic opioids represented by fentanyl. Naloxone, which is a FDA-approved reversal agent, antagonizes opioids through competitive binding at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24fbd23f7f4cee63b262791b88ea486c
https://doi.org/10.1021/acs.jcim.3c00069
https://doi.org/10.1021/acs.jcim.3c00069
Autor:
Paween Mahinthichaichan, Ruibin Liu, Quynh N Vo, Christopher R Ellis, Lidiya Stavitskaya, Jana Shen
Publikováno v:
bioRxiv
The nation's opioid overdose deaths reached an all-time high in 2021. The majority of deaths are due to synthetic opioids represented by fentanyl. Naloxone, which is an FDA-approved reversal agent, antagonizes opioids through competitive binding at t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f13a007ff31221d9315fb79f958b814
https://doi.org/10.1101/2023.03.06.531338
https://doi.org/10.1101/2023.03.06.531338
Publikováno v:
JACS Au
JACS Au, Vol 1, Iss 12, Pp 2208-2215 (2021)
JACS Au, Vol 1, Iss 12, Pp 2208-2215 (2021)
Driven by illicit fentanyl, opioid related deaths have reached the highest level in 2020. Currently, an opioid overdose is resuscitated by the use of naloxone, which competitively binds and antagonizes the μ-opioid receptor (mOR). Thus, knowledge of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8df4e995bf91173b227f30a77be64f27
https://doi.org/10.1021/jacsau.1c00341
https://doi.org/10.1021/jacsau.1c00341
Driven by illicit fentanyl, opioid related deaths have reached the highest level in 2020. Currently, an opioid over-dose is resuscitated by the use of naloxone, which competitively binds and antagonizes the µ-opioid receptor (mOR). Thus, knowledge o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14cbe99680baf282d4f1a5030c098ef1
https://doi.org/10.1101/2021.04.25.441335
https://doi.org/10.1101/2021.04.25.441335
Publikováno v:
Nature Communications
Research Square
article-version (status) pre
article-version (number) 1
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
bioRxiv
article-version (number) 2
Research Square
article-version (status) pre
article-version (number) 1
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
bioRxiv
article-version (number) 2
Roughly half of the drug overdose-related deaths in the United States are related to synthetic opioids represented by fentanyl which is a potent agonist of mu-opioid receptor (mOR). In recent years, X-ray crystal structures of mOR in complex with mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c7127ac4808ff3ede6b016cd313b41
http://europepmc.org/articles/PMC7881245
http://europepmc.org/articles/PMC7881245
Publikováno v:
Chemical Physics Letters. 671:58-62
We report a classical rate theory approach to predict the exchange mechanism that occurs between water and aqueous uranyl ion. Using our water and ion-water polarizable force field and molecular dynamics techniques, we computed the potentials of mean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3c6b8b7c08003b0e6cb3d15160b7a55
https://doi.org/10.1016/j.cplett.2017.01.020
https://doi.org/10.1016/j.cplett.2017.01.020
Publikováno v:
The journal of physical chemistry. B. 123(3)
In solvent extraction processes for recovering metal ions from used nuclear fuel, as well as other industrial applications, a better understanding of the metal complex phase transfer phenomenon would greatly aid ligand design and process optimization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b77e5adec549f0046da90240347308c
https://pubmed.ncbi.nlm.nih.gov/30584762
https://pubmed.ncbi.nlm.nih.gov/30584762
Publikováno v:
Oncogene. 5/30/2002, Vol. 21 Issue 24, p3864. 8p. 5 Diagrams.