Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Quy T. Nguyen"'
Publikováno v:
Obstetrics and Gynecology International, Vol 2016 (2016)
Background. Accurate timing of antenatal corticosteroids (ACS) has resulted in improved neonatal outcomes. Objectives. Our primary objective was to determine predictors for optimal timing of ACS in women presenting with spontaneous preterm labor. Stu
Externí odkaz:
https://doaj.org/article/3fa0fe4e371e4160b66823c2611db564
Publikováno v:
2022 RIVF International Conference on Computing and Communication Technologies (RIVF).
Autor:
Amanda M Opaluch, Monika Schneider, Chih-yuan Chiang, Quy T Nguyen, Ana M Maestre, Lubbertus C F Mulder, Ismael Secundino, Paul D De Jesus, Renate König, Viviana Simon, Victor Nizet, Graham MacLeod, Susannah Varmuza, Ana Fernandez-Sesma, Sumit K Chanda
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89284 (2014)
Innate immune sensors such as Toll-like receptors (TLRs) differentially utilize adaptor proteins and additional molecular mediators to ensure robust and precise immune responses to pathogen challenge. Through a gain-of-function genetic screen, we ide
Externí odkaz:
https://doaj.org/article/8a1d8360ade647799e0b14344a763138
Autor:
Simon Langer, Lars Pache, Paul D. De Jesus, Sunnie M. Yoh, Kevin C. Olivieri, Alex J. Portillo, Prashant Jain, Quy T. Nguyen, Sumit K. Chanda, Guney Boso, Stephen Soonthornvacharin
Publikováno v:
Cell Reports, Vol 22, Iss 9, Pp 2493-2503 (2018)
Summary: Accessory proteins of lentiviruses, such as HIV-1, target cellular restriction factors to enhance viral replication. Systematic analyses of proteins that are targeted for degradation by HIV-1 accessory proteins may provide a better understan
Publikováno v:
Language Resources and Evaluation. 52:269-315
Treebanks are important resources for researchers in natural language processing. They provide training and testing materials so that different algorithms can be compared. However, it is not a trivial task to construct high-quality treebanks. We have
Autor:
Megan L. Shaw, Lars Pache, Randy A. Albrecht, Dario Andenmatten, Lubbertus C. F. Mulder, Guojun Wang, Abraham L. Brass, Marie O. Pohl, Adolfo García-Sastre, Yingyao Zhou, Michael Shales, Nir Hacohen, Doug Sanders, Stephen J. Elledge, David A. Stein, Michael A. White, Renate König, Thomas F. Meyer, Alexander Karlas, Paul DeJesus, Sagi Shapira, Maria G. Gonzalez, Jianwei Che, Gwen Jang, Balaji Manicassamy, Nevan J. Krogan, Erik Verschueren, Silke Stertz, Ariel Rodriguez-Frandsen, Quy T. Nguyen, Andre Gatorano, Emilio Yángüez, Hong M. Moulton, Jeffrey R. Johnson, Shashank Tripathi, Tasha L. Johnson, Sumit K. Chanda
Publikováno v:
Cell Host & Microbe. 18(6):723-735
Several systems-level datasets designed to dissect host-pathogen interactions during influenza A infection have been reported. However, apparent discordance among these data has hampered their full utility toward advancing mechanistic and therapeutic
Publikováno v:
Obstetrics and Gynecology International
Obstetrics and Gynecology International, Vol 2016 (2016)
Obstetrics and Gynecology International, Vol 2016 (2016)
Background. Accurate timing of antenatal corticosteroids (ACS) has resulted in improved neonatal outcomes.Objectives. Our primary objective was to determine predictors for optimal timing of ACS in women presenting with spontaneous preterm labor.Study
Autor:
Ismael Secundino, Loren Miraglia, Paul D. De Jesus, Ana Fernandez-Sesma, Quy T. Nguyen, Irene Ramos, Chih-yuan Chiang, Yingyao Zhou, Ghislain M. C. Bonamy, Genevieve Welch, Victor Nizet, Ana M. Maestre, Anthony P. Orth, Amanda M. Opaluch, Gregory M. Barton, Alex Engel, Sumit K. Chanda
Publikováno v:
Cell Host & Microbe. 11:306-318
SummaryPathogens commonly utilize endocytic pathways to gain cellular access. The endosomal pattern recognition receptors TLR7 and TLR9 detect pathogen-encoded nucleic acids to initiate MyD88-dependent proinflammatory responses to microbial infection
Autor:
Peter Palese, Adolfo García-Sastre, Quy T. Nguyen, Renate Koenig, Kelli Kuhen, Paul D. De Jesus, Atsushi Inoue, Pablo Abreu, Paul Anderson, Megan L. Shaw, Puiying A. Mak, Elisa Barile, Zhong Chen, Silke Stertz, Sumit K. Chanda, Maurizio Pellecchia, Kris M. White
Publikováno v:
ACS Infectious Diseases
An ultrahigh-throughput screen was performed to identify novel small molecule inhibitors of influenza virus replication. The screen employed a recombinant influenza A/WSN/33 virus expressing Renilla luciferase and yielded a hit rate of 0.5%, of which
Autor:
Stephen Soonthornvacharin, Yingyao Zhou, Ariel Rodriguez-Frandsen, Elisa de Castro, Hong M. Moulton, Maria Teresa Sánchez-Aparicio, Adolfo García-Sastre, David A. Stein, Vinod Balasubramaniam, Shashank Tripathi, Atsushi Inoue, Nicholas J Huffmaster, Felipe Galvez, Paul D. De Jesus, Quy T. Nguyen, Renate König, Sumit K. Chanda, Sunnie M. Yoh, Nevan J. Krogan
Publikováno v:
Nature microbiology
Retinoic acid-inducible gene I (RIG-I) receptor recognizes 5'-triphosphorylated RNA and triggers a signalling cascade that results in the induction of type-I interferon (IFN)-dependent responses. Its precise regulation represents a pivotal balance be