Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Qusai Y. Al-Share"'
Autor:
Lucia Russo, Hilda E. Ghadieh, Simona S. Ghanem, Qusai Y. Al-Share, Zachary N. Smiley, Cara Gatto-Weis, Emily L. Esakov, Marcia F. McInerney, Garrett Heinrich, Xin Tong, Lei Yin, Sonia M. Najjar
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 12, Pp 2163-2175 (2016)
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin sensitivity by promoting hepatic insulin clearance and mediating suppression of fatty acid synthase activity. Feeding C57BL/6J male mice with a high-fat (HF) diet f
Externí odkaz:
https://doaj.org/article/f7f6fe2e102a48d98a2c1e9bb9c83e65
Autor:
Shoroq M Altawalbeh, Basima A Almomani, Qais Alefan, Suleiman Mohammad Momany, Qusai Y Al-Share
Publikováno v:
International Journal of Pharmacy Practice. 30:457-465
Objectives Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Concerns have been raised about the influence of adverse drug effects on patient’s health-related quality of life (HRQoL) in COPD patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c4093fdfb82cc47e47a623f9c701b0
https://doi.org/10.1093/ijpp/riac052
https://doi.org/10.1093/ijpp/riac052
Autor:
Sumona Ghosh Lester, lucia eRusso, Simona Simon Ghanem, Saja Sadik Khuder, Anthony Michael DeAngelis, Emily L Esakov, Thomas A Bowman, Garrett eHeinrich, Qusai Y Al-Share, Marcia F McInerney, William M Philbrick, Sonia Michael Najjar
Publikováno v:
Frontiers in Endocrinology, Vol 6 (2015)
CEACAM1 promotes insulin extraction, an event that occurs mainly in liver. Phenocopying global Ceacam1 null mice (Cc1–/–), C57/BL6J mice fed a high-fat diet exhibited reduced hepatic CEACAM1 levels and impaired insulin clearance, followed by hype
Externí odkaz:
https://doaj.org/article/0892afe37c8447e6bba827286aaade08
Autor:
Silas A Culver, Syed Quadri, Kelly L. Ledford, Caixia Li, Qusai Y. Al-Share, Helmy M. Siragy, Hilda E. Ghadieh, Sonia M. Najjar
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 309:E802-E810
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAMl), a substrate of the insulin receptor tyrosine kinase, regulates insulin action by promoting insulin clearance. Global null mutation of Ceacam1 gene ( Cc1−/−) results in features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3f6a908d15d8d1e6af64379cafa3eb
https://doi.org/10.1152/ajpendo.00158.2015
https://doi.org/10.1152/ajpendo.00158.2015
Autor:
Meenakshi Kaw, Thomas A. Bowman, Lucia Russo, Payal R. Patel, Jason K. Kim, Rohit N. Kulkarni, Simon L. Abdallah, Anthony M. DeAngelis, Sumona Ghosh Lester, Garrett Heinrich, Christian K. Raphael, Sonia M. Najjar, Sadeesh K. Ramakrishnan, William M. Philbrick, Qusai Y. Al-Share, Abraham D. Lee, Andrea Jung Kim
Publikováno v:
Diabetes
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin sensitivity by promoting hepatic insulin clearance. Liver-specific inactivation or global null-mutation of Ceacam1 impairs hepatic insulin extraction to cause chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1104a144ff045409495ab7f59c319052
https://doi.org/10.2337/db14-1772
https://doi.org/10.2337/db14-1772
Autor:
Khadijeh Rezaei, Simona S. Ghanem, Lei Yin, Garrett Heinrich, Sonia M. Najjar, Harrison T. Muturi, Anthony M. DeAngelis, Deqiang Zhang, Robert S. Garofalo, Hilda E. Ghadieh, Thomas A. Bowman, Qusai Y. Al-Share
Publikováno v:
Frontiers in Endocrinology
Impairment of insulin clearance is being increasingly recognized as a critical step in the development of insulin resistance and metabolic disease. The carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) promotes insulin clearance. Nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e002818b3fc58662596b061ef047e411
https://doi.org/10.3389/fendo.2017.00054
https://doi.org/10.3389/fendo.2017.00054
Autor:
Garrett Heinrich, Deqiang Zhang, Khadijeh Rezaei, Robert S. Garofalo, Lei Yin, Qusai Y. Al-Share, Sonia M. Najjar, Harrison T. Muturi, Hilda E. Ghadieh, Thomas A. Bowman, Simona S. Ghanem
Publikováno v:
Frontiers in Endocrinology
The pathogenesis of human non-alcoholic fatty liver disease (NAFLD) remains unclear, in particular in the context of its relationship to insulin resistance and visceral obesity. Work on the carcinoembryonic antigen-related cell adhesion molecule 1 (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d24e7f891792b8159681fe4d97c8d61
https://doi.org/10.3389/fendo.2017.00008
https://doi.org/10.3389/fendo.2017.00008
Autor:
Marcia F. McInerney, Simona S. Ghanem, Cara Gatto-Weis, Hilda E. Ghadieh, Lei Yin, Emily Esakov, Qusai Y. Al-Share, Sonia M. Najjar, Xin Tong, Zachary N. Smiley, Lucia Russo, Garrett Heinrich
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 12, Pp 2163-2175 (2016)
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates insulin sensitivity by promoting hepatic insulin clearance and mediating suppression of fatty acid synthase activity. Feeding C57BL/6J male mice with a high-fat (HF) diet f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4941c0eb4836cd2e0bd395fb9e01f0f2
https://europepmc.org/articles/PMC5321226/
https://europepmc.org/articles/PMC5321226/
Autor:
Sumona Ghosh Lester, lucia eRusso, Simona Simon Ghanem, Saja Sadik Khuder, Anthony Michael DeAngelis, Emily L Esakov, Thomas A Bowman, Garrett eHeinrich, Qusai Y Al-Share, Marcia F McInerney, William M Philbrick, Sonia Michael Najjar
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 6 (2015)
Frontiers in Endocrinology, Vol 6 (2015)
CEACAM1 promotes insulin extraction, an event that occurs mainly in liver. Phenocopying global Ceacam1 null mice (Cc1–/–), C57/BL6J mice fed a high-fat diet exhibited reduced hepatic CEACAM1 levels and impaired insulin clearance, followed by hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e2ef7196820f2826fa669fd6330b2a
http://europepmc.org/articles/PMC4522571
http://europepmc.org/articles/PMC4522571
Autor:
Denisa May, Holger Kalthoff, Qusai Y. Al-Share, George A. Abou-Rjaily, Sue-Hwa Lin, Michael Neumaier, Randall J. Ruch, Anthony M. DeAngelis, Sang Jun Lee, Sonia M. Najjar
Publikováno v:
Journal of Clinical Investigation. 114:944-952
Phosphorylation of the cell adhesion protein CEACAM1 increases insulin sensitivity and decreases insulin-dependent mitogenesis in vivo. Here we show that CEACAM1 is a substrate of the EGFR and that upon being phosphorylated, CEACAM1 reduces EGFR-medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fc64dcfc99c398e01501f795fa49fb
https://doi.org/10.1172/jci200421786
https://doi.org/10.1172/jci200421786