Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Qurratulain Aftab"'
Autor:
Qurratulain Aftab, Marc Mesnil, Emmanuel Ojefua, Alisha Poole, Jenna Noordenbos, Pierre-Olivier Strale, Chris Sitko, Caitlin Le, Nikolay Stoynov, Leonard J. Foster, Wun-Chey Sin, Christian C. Naus, Vincent C. Chen
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Extracellular matrix (ECM) remodeling, degradation and glioma cell motility are critical aspects of glioblastoma multiforme (GBM). Despite being a rich source of potential biomarkers and targets for therapeutic advance, the dynamic changes occurring
Externí odkaz:
https://doaj.org/article/4c81f1bf13534e85868d69ab4051c20a
Autor:
John J. Shin, Qurratulain Aftab, Pamela Austin, Jennifer A. McQueen, Tak Poon, Shu Chen Li, Barry P. Young, Calvin D. Roskelley, Christopher J. R. Loewen
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 9, Pp 1039-1049 (2016)
A hallmark of all primary and metastatic tumours is their high rate of glucose uptake and glycolysis. A consequence of the glycolytic phenotype is the accumulation of metabolic acid; hence, tumour cells experience considerable intracellular acid stre
Externí odkaz:
https://doaj.org/article/e4ad6a9d9de942b1a8efd2584d4da9bd
Autor:
Leonard J. Foster, Pierre-Olivier Strale, Marc Mesnil, Wun-Chey Sin, Jenna Noordenbos, Vincent C. Chen, Alisha T Poole, Christian C. Naus, Qurratulain Aftab, Caitlin Le, Emmanuel Ojefua, Chris Sitko, Nikolay Stoynov
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Frontiers, 2019, 13, ⟨10.3389/fnins.2019.00143⟩
Frontiers in Neuroscience, Vol 13 (2019)
Frontiers in Neuroscience, Frontiers, 2019, 13, ⟨10.3389/fnins.2019.00143⟩
Frontiers in Neuroscience, Vol 13 (2019)
Extracellular matrix (ECM) remodeling, degradation and glioma cell motility are critical aspects of glioblastoma multiforme (GBM). Despite being a rich source of potential biomarkers and targets for therapeutic advance, the dynamic changes occurring
Publikováno v:
Oncogene. 35:1504-1516
Reactive astrocytes are integral to the glioma microenvironment. Connexin43 (Cx43) is a major gap junction protein in astrocytes and its expression is enhanced significantly in glioma-associated astrocytes, especially at the peri-tumoral region. Alth
Publikováno v:
Oncotarget
Glioblastoma Multiforme (GBM), an aggressive form of adult brain tumor, is difficult to treat due to its invasive nature. One of the molecular changes observed in GBM is a decrease in the expression of the gap junction protein Connexin43 (Cx43); howe
Autor:
Tak Poon, Pamela Austin, Qurratulain Aftab, John J.H. Shin, Jennifer McQueen, Barry P. Young, Christopher J. R. Loewen, Calvin D. Roskelley, Shu Chen Li
Publikováno v:
Disease Models & Mechanisms.
A hallmark of all primary and metastatic tumours is their high rate of glucose uptake and glycolysis. A consequence of the glycolytic phenotype is the accumulation of metabolic acid; hence, tumour cells experience considerable intracellular acid stre
Publikováno v:
Seminars in celldevelopmental biology. 50
Cell migration is critical for cell differentiation, tissue formation and organ development. Several mechanisms come to play in the process of cell migration, orchestrating changes in cell polarity, adhesion, process extension and motility. Recent fi
Publikováno v:
Glia. 55:1554-1564
Gliomas are particularly difficult to cure owing largely to their invasive nature. The neoplastic changes of astrocytes which give rise to these tumors frequently include a reduction of connexin43 (Cx43), the most abundant connexin isoform expressed
Autor:
Christian C. Naus, Xiaoting Hong, Shannon Lozinsky, Vincent C. Chen, Qurratulain Aftab, Noreen Ma, Paul R. Gielen, Wun Chey Sin
Publikováno v:
Neuropharmacology, 75, pp. 539-48
Neuropharmacology, 75, 539-48
Neuropharmacology, 75, 539-48
Item does not contain fulltext Glioblastoma multiforme (GBM) is the most aggressive astrocytoma, and therapeutic options are generally limited to surgical resection, radiotherapy, and Temozolomide (TMZ) chemotherapy. TMZ is a DNA alkylating agent tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52c3fc6129c5ab87a08781607c2d33f
https://doi.org/10.1016/j.neuropharm.2013.05.002
https://doi.org/10.1016/j.neuropharm.2013.05.002