Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Quoc C. Le"'
Autor:
Quoc C. Le, Li-Teh Wu, William H. Baricos, Sudhir V. Shah, Kazunori Hanada, Elliott Shaw, Shirley L. Cortez
Publikováno v:
Archives of Biochemistry and Biophysics. 288:468-472
We have utilized specific, irreversible inhibitors of cysteine proteinases to examine the role of renal cathepsin B and cathepsin L in the proteinuria which occurs in an experimental model of human glomerular disease. Administration of trans-epoxysuc
Publikováno v:
American Journal of Physiology-Renal Physiology. 260:F555-F561
We have utilized [3H] gelatin to document high activity of a metalloproteinase present in freshly isolated rat glomeruli. [3H] gelatin degradation by glomeruli was markedly inhibited by EDTA (10 mM: -89 +/- 2.3%) and o-phenanthroline (2 mM: -72 +/- 0
Autor:
Youwen Zhou, Quoc C. Le, Sudhir V. Shah, Sally O'Connor, Rudene M. Dicarlo, Shirley L. Cortez, William H. Baricos
Publikováno v:
Kidney International. 38:395-401
Glomerular basement membrane degradation by endogenous cysteine proteinases in isolated rat glomeruli. Recent in vitro and in vivo studies suggest that cysteine proteinases may play an important role in degradation of the glomerular basement membrane
Publikováno v:
American journal of nephrology. 18(1)
A 65-year-old woman developed nephrotic syndrome 7 years after receiving a cadaveric renal allograft. Renal biopsy and clinical laboratory evaluation revealed the underlying disease process to be AL amyloidosis. To our knowledge, this is the first re
Autor:
Kelly L. Hudkins, Connie L. Davis, Richard J. Johnson, Cecilia M. Giachelli, Stephan Segerer, Charles E. Alpers, Quoc C. Le
Publikováno v:
Kidney International. (2):635-640
Osteopontin expression in human cyclosporine toxicity . Background Osteopontin is a secreted phosphoprotein that has a number of diverse biological functions, including cell signaling, mediation of cell adhesion, migration, and chemoattraction of mon