Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Qunzhao Wang"'
Autor:
Stephen J. Klawa, Michelle Lee, Kyle D. Riker, Tengyue Jian, Qunzhao Wang, Yuan Gao, Margaret L. Daly, Shreeya Bhonge, W. Seth Childers, Tolulope O. Omosun, Anil K. Mehta, David G. Lynn, Ronit Freeman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract In neurodegenerative diseases, polymorphism and supramolecular assembly of β-sheet amyloids are implicated in many different etiologies and may adopt either a left- or right-handed supramolecular chirality. Yet, the underlying principles of
Externí odkaz:
https://doaj.org/article/6511971a5a27462aa4ef6f1dc86b0364
Autor:
Matthew M. Anttila, Brianna M. Vickerman, Qunzhao Wang, David S. Lawrence, Nancy L. Allbritton
Publikováno v:
Analytical Chemistry. 93:16664-16672
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c042a36d99de2aa9188469a0640e0243
https://doi.org/10.1021/acs.analchem.1c04225
https://doi.org/10.1021/acs.analchem.1c04225
Autor:
Song Ding, Rishi R. Rampersad, Qunzhao Wang, Emily M. Rabjohns, David S. Lawrence, Amanda M Eudy, Emilia M. Zywot, Lauren Haar, Joshua G. Welfare, Victoria A. Wickenheisser, Teresa K. Tarrant, Natalia Orlova
Publikováno v:
Adv Ther (Weinh)
Arthritis is a leading cause of disability in adults, which can be intensely incapacitating. The location and intensity of the pain is both subjective and challenging to manage. Consequently, patient-directed delivery of anti-inflammatories is an ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c938e4d194fe49941ba3cc6bd6d2a9fd
https://europepmc.org/articles/PMC9075171/
https://europepmc.org/articles/PMC9075171/
Autor:
Teresa Tarrant, qunzhao wang, Natalia Orlova, Victoria Wickenheisser, Christina Marvin, Lauren Haar, David Lawrence, Song Ding, Emily Rabjohns, Brianna Vickerman, Emilia Zywot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f7276e3e4d63f04eeb6421927e48d45
https://doi.org/10.1021/scimeetings.0c07032
https://doi.org/10.1021/scimeetings.0c07032
Chemical cytometry, sensitive analytical measurements of single cells, reveals inherent heterogeneity of cells within a population which is masked or averaged out when using bulk analysis techniques. A particular challenge of chemical cytometry is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d81fb19f7458c4c8d28a3240575e405
https://doi.org/10.1016/bs.mie.2019.02.023
https://doi.org/10.1016/bs.mie.2019.02.023
Autor:
David S. Lawrence, Qunzhao Wang, Colin P. O'Banion, Melanie A. Priestman, Luong T. Nguyen, Stephen P. Holly, Leslie V. Parise
Publikováno v:
Angewandte Chemie International Edition. 55:950-954
Although peptide-based therapeutics are finding increasing application in the clinic, extensive structural modification is typically required to prevent their rapid degradation by proteases in the blood. We have evaluated the ability of erythrocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b643ba26f276098d0036ad4f044e9a5
https://doi.org/10.1002/anie.201508767
https://doi.org/10.1002/anie.201508767
Autor:
Melanie A. Priestman, Finith E. Jernigan, Qunzhao Wang, Marion Schmidt, David S. Lawrence, Ruma Chowdhury
Publikováno v:
ACS Chemical Biology
The proteasome, a validated anticancer target, participates in an array of biochemical activities, which range from the proteolysis of defective proteins to antigen presentation. We report the preparation of biochemically and photophysically distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127d50c8dec5a984fa451041b20a9945
http://europepmc.org/articles/PMC4340355
http://europepmc.org/articles/PMC4340355
Autor:
Qunzhao Wang, S. Gabriela Herrera-Loeza, Angela Proctor, Jen Jen Yeh, David S. Lawrence, Nancy L. Allbritton
Publikováno v:
Analytical Chemistry
An optimized peptide substrate was used to measure protein kinase B (PKB) activity in single cells. The peptide substrate was introduced into single cells, and capillary electrophoresis was used to separate and quantify nonphosphorylated and phosphor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7729d48c680a86d8a265c080c02ee63f
http://europepmc.org/articles/PMC4018172
http://europepmc.org/articles/PMC4018172
Autor:
Nancy L. Allbritton, David S. Lawrence, Imola G. Zigoneanu, Qunzhao Wang, Christopher E. Sims, Angela Proctor
A peptidase-resistant ABL kinase substrate was developed by identifying protease-susceptible bonds on an ABL substrate peptide and replacing flanking amino acids with non-native amino acids. After an iterative design process, the lead, or designed, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120af827f1f29b78d1c6c301c184af20
https://europepmc.org/articles/PMC5111365/
https://europepmc.org/articles/PMC5111365/
Publikováno v:
Angewandte Chemie (International ed. in English). 55(42)
Tools to evaluate oncogenic kinase activity in small clinical samples have the power to guide precision medicine in oncology. Existing platforms have demonstrated impressive insights into the activity of protein kinases, but these technologies are un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99771aafda44fec41643367715907c4
https://pubmed.ncbi.nlm.nih.gov/27647713
https://pubmed.ncbi.nlm.nih.gov/27647713