Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Qungen Xiao"'
Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
Autor:
Huan Li, Chao Song, Yang Zhang, Guohao Liu, Hailong Mi, Yachao Li, Zhiye Chen, Xiaoyu Ma, Po Zhang, Lidong Cheng, Peng Peng, Hongtao Zhu, Zirong Chen, Minhai Dong, Sui Chen, Hao Meng, QunGen Xiao, Honglian Li, Qiulian Wu, Baofeng Wang, Suojun Zhang, Kai Shu, Feng Wan, Dongsheng Guo, Wenchao Zhou, Lin Zhou, Feng Mao, Jeremy N. Rich, Xingjiang Yu
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Glioblastoma (GBM) is a lethal cancer characterized by hypervascularity and necrosis associated with hypoxia. Here, it is found that hypoxia preferentially induces the actin‐binding protein, Transgelin (TAGLN), in GBM stem cells (GSCs). Me
Externí odkaz:
https://doaj.org/article/95216e81a5c74d7e8e6af9ccdf165215
Autor:
Ting Li, Wei Li, Ying Li, Sui Chen, Qian Gao, Xiaopeng Li, Po Zhang, Jinyang Hu, Feng Dong, You He, Xianyou Xia, Fangling Cheng, Xiaoshuang Hou, Guohao Liu, Minhai Dong, Qungen Xiao, Xingjiang Yu, Guifa Xi, Dongsheng Guo, Xudong Wu, Baofeng Wang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Glioblastoma (GBM) is the most common malignant brain tumor with poor clinical outcomes. Immunotherapy has recently been an attractive and promising treatment of extracranial malignancies, however, most of clinical trials for GBM immunothe
Externí odkaz:
https://doaj.org/article/d100b5cfc0af4ee5972992117bc14884
Autor:
Cuifang Ye, Huan Li, Yachao Li, Yang Zhang, Guohao Liu, Hailong Mi, Honglian Li, Qungen Xiao, Li Niu, Xingjiang Yu
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104872- (2022)
Summary: Glioma stem cells (GSCs) in the hypoxic niches contribute to tumor initiation, progression, and recurrence in glioblastoma (GBM). Hypoxia induces release of high-mobility group box 1 (HMGB1) from tumor cells, promoting the development of tum
Externí odkaz:
https://doaj.org/article/cd8cbc0aa2f84355b2eceee8f11724a6
Autor:
Yusi Chen, Feng Hu, Junwen Wang, Kuan Huang, Weihua Liu, Yutang Tan, Kai Zhao, Qungen Xiao, Ting Lei, Kai Shu
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
BackgroundCraniopharyngioma (CP) with tumoral hemorrhage is a very rare syndrome presenting with various manifestation and unfavorable outcomes. The current retrospective study was performed to summarize the clinical features of CP with tumoral hemor
Externí odkaz:
https://doaj.org/article/3b7a7a3088794035b269890cea6d25d8
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Glioblastoma Multiforme (GBM) is the most common and aggressive form of intracranial tumors with poor prognosis. In recent years, tumor immunotherapy has been an attractive strategy for a variety of tumors. Currently, most immunotherapies take advant
Externí odkaz:
https://doaj.org/article/0aab5de088004c83bd270a19e5532c1f
Autor:
Fangling Cheng, Po Zhang, Qungen Xiao, Youwei Li, Minhai Dong, Heping Wang, Dong Kuang, Yue He, Qiuhong Duan, Feng Mao, Baofeng Wang, Dongsheng Guo
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Externí odkaz:
https://doaj.org/article/38a072e0706b49a69397f617dbe2d4b4
Autor:
Fangling Cheng, Po Zhang, Qungen Xiao, Youwei Li, Minhai Dong, Heping Wang, Dong Kuang, Yue He, Qiuhong Duan, Feng Mao, Baofeng Wang, Dongsheng Guo
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Glioblastoma is a highly lethal type of primary brain tumor that exhibits unrestricted growth and aggressive invasion capabilities, leading to a dismal prognosis despite a multitude of therapies. Multiple alterations in the expression level of genes
Externí odkaz:
https://doaj.org/article/89d48327699e46a99320be1c638c3427
Autor:
Qungen Xiao, Yihu Tan, Yang Guo, Hongkuan Yang, Feng Mao, Ruifan Xie, Baofeng Wang, Ting Lei, Dongsheng Guo
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111419 (2014)
The human leucine-rich repeats and immunoglobulin-like domains (LRIG) gene family contains LRIG1, 2 and 3, encoding integral membrane proteins with an ectodomain, a transmembrane domain and a cytoplasmic tail. LRIG1 negatively regulates multiple rece
Externí odkaz:
https://doaj.org/article/55529f4309e34ac0ac68f5d115c859a5
Autor:
Guohao Liu, Po Zhang, Sui Chen, Zirong Chen, Yanmei Qiu, Peng Peng, Wenda Huang, Fangling Cheng, Yang Zhang, Huan Li, Qungen Xiao, Feng Mao, Baofeng Wang, Xiaobing Jiang, Feng Wan, Dongsheng Guo, Xingjiang Yu
Publikováno v:
Neuro-Oncology.
Background Glioma stem cells (GSCs) are a subpopulation of tumor cells with self-renewal and tumorigenic capabilities in glioblastomas (GBMs). Diffuse infiltration of GSCs facilitates tumor progression and frustrates efforts at effective treatment. F
Autor:
Jinyang Hu, Feng Dong, You He, Xianyou Xia, Fangling Cheng, Sui Chen, Xiaoshuang Hou, Po Zhang, Guohao Liu, Ying Li, Qian Gao, Minhai Dong, Ting Li, Wei Li, Qungen Xiao, Xiaopeng Li, Xingjiang Yu, Guifa Xi, Dongsheng Guo, Xudong Wu, Baofeng Wang
Publikováno v:
Journal for immunotherapy of cancer. 10(9)
BackgroundGlioblastoma (GBM) is the most common malignant brain tumor with poor clinical outcomes. Immunotherapy has recently been an attractive and promising treatment of extracranial malignancies, however, most of clinical trials for GBM immunother