Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Qun Ying Lei"'
Autor:
Jing He, Mingen Lin, Xinchao Zhang, Ruonan Zhang, Tongguan Tian, Yuefan Zhou, Wenjing Dong, Yajing Yang, Xue Sun, Yue Dai, Yue Xu, Zhenru Zhang, Ming Xu, Qun-Ying Lei, Yanping Xu, Lei Lv
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Tumor development, involving both cell growth (mass accumulation) and cell proliferation, is a complex process governed by the interplay of multiple signaling pathways. TET2 mainly functions as a DNA dioxygenase, which modulates gene express
Externí odkaz:
https://doaj.org/article/f14e9dc959e64d9eb8fb2ae99ea97411
Autor:
Yuan Shen, Liang-Liang Zheng, Cai-Yun Fang, Yao-Yao Xu, Chao Wang, Jin-Tao Li, Ming-Zhu Lei, Miao Yin, Hao-Jie Lu, Qun-Ying Lei, Jia Qu
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113720- (2024)
Summary: LMNA gene mutation can cause muscular dystrophy, and post-translational modification plays a critical role in regulating its function. Here, we identify that lamin A is palmitoylated at cysteine 522, 588, and 591 residues, which are reversel
Externí odkaz:
https://doaj.org/article/3f01aba67c1c4caab980cf48358b8d03
Autor:
Junjiao Song, Hongquan Li, Yanfang Liu, Xinrong Li, Qili Shi, Qun‐Ying Lei, Weiguo Hu, Shenglin Huang, Zhiao Chen, Xianghuo He
Publikováno v:
Advanced Science, Vol 10, Iss 26, Pp n/a-n/a (2023)
Abstract Aldolase A (ALDOA), a crucial glycolytic enzyme, is often aberrantly expressed in various types of cancer. Although ALDOA has been reported to play additional roles beyond its conventional enzymatic role, its nonmetabolic function and underl
Externí odkaz:
https://doaj.org/article/4c6bf9d8025849eeaa270cbc15be707a
Autor:
Xinyue Lv, Peipei Ding, Luying Li, Ling Li, Danlei Zhou, Xiaochao Wang, Jianfeng Chen, Wei Zhang, Qi Wang, Tian Liao, Wenyu Wen, Dawang Zhou, Qing-Hai Ji, Xianghuo He, Qun-Ying Lei, Weiguo Hu
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101766- (2023)
Sufficient evidence has linked many different types of cancers and T2D through shared risk factors; however, the underlying mechanisms are not fully understood. α-Hydroxybutyrate (α-HB), a byproduct metabolite increased in diabetes and cancer, incl
Externí odkaz:
https://doaj.org/article/cacb6d4737814e1abb411fe1c2ef9871
Autor:
Jin-Tao Li, Hai Yang, Ming-Zhu Lei, Wei-Ping Zhu, Ying Su, Kai-Yue Li, Wen-Ying Zhu, Jian Wang, Lei Zhang, Jia Qu, Lei Lv, Hao-Jie Lu, Zheng-Jun Chen, Lu Wang, Miao Yin, Qun-Ying Lei
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-12 (2022)
Abstract Folic acid, served as dietary supplement, is closely linked to one-carbon metabolism and methionine metabolism. Previous clinical evidence indicated that folic acid supplementation displays dual effect on cancer development, promoting or sup
Externí odkaz:
https://doaj.org/article/25ed74a1881f41afbdcc36be38e5204e
Autor:
Zhiyuan Xiang, Guixue Hou, Shanliang Zheng, Minqiao Lu, Tianyu Li, Qingyu Lin, Hao Liu, Xingwen Wang, Tianqi Guan, Yuhan Wei, Wenxin Zhang, Yi Zhang, Chaoran Liu, Li Li, Qun-ying Lei, Ying Hu
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 9/10/2024, Vol. 121 Issue 37, p1-12, 32p
Autor:
Jing He, Mingen Lin, Xinchao Zhang, Ruonan Zhang, Tongguan Tian, Yuefan Zhou, Wenjing Dong, Yajing Yang, Xue Sun, Yue Dai, Yue Xu, Zhenru Zhang, Ming Xu, Qun-Ying Lei, Yanping Xu, Lei Lv
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/29dfc5f129eb43fcb2310ecd9839a26c
Autor:
Jiahui Xu, Xiaoli Yang, Qiaodan Deng, Cong Yang, Dong Wang, Guojuan Jiang, Xiaohong Yao, Xueyan He, Jiajun Ding, Jiankun Qiang, Juchuanli Tu, Rui zhang, Qun-Ying Lei, Zhi-min Shao, Xiuwu Bian, Ronggui Hu, Lixing Zhang, Suling Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Vasculogenic mimicry (VM) contributes to the development of triple-negative breast cancer. In this study, the authors show that TEM8 is expressed in VM-forming breast cancer stem cells and it promotes stemness and VM differentiation capacity through
Externí odkaz:
https://doaj.org/article/4d5dff66ab924a66a148c3c003c9bdec
Autor:
Hongquan Li, Junjiao Song, Yifei He, Yizhe Liu, Zhen Liu, Weili Sun, Weiguo Hu, Qun‐Ying Lei, Xin Hu, Zhiao Chen, Xianghuo He
Publikováno v:
Advanced Science, Vol 9, Iss 21, Pp n/a-n/a (2022)
Abstract Metabolic reprogramming is often observed in carcinogenesis, but little is known about the aberrant metabolic genes involved in the tumorigenicity and maintenance of stemness in cancer cells. Sixty‐seven oncogenic metabolism‐related gene
Externí odkaz:
https://doaj.org/article/dbbc6bbbbdca40fe97cc2f6f7db23a39
Autor:
Wei Zhang, Xin Zhang, Sheng Huang, Jianfeng Chen, Peipei Ding, Qi Wang, Luying Li, Xinyue Lv, Ling Li, Pingzhao Zhang, Danlei Zhou, Wenyu Wen, Yiping Wang, Qun‐Ying Lei, Jiong Wu, Weiguo Hu
Publikováno v:
Molecular Oncology, Vol 15, Iss 5, Pp 1466-1485 (2021)
Tumor growth, especially in the late stage, requires adequate nutrients and rich vasculature, in which PKM2 plays a convergent role. It has been reported that PKM2, together with FOXM1D, is upregulated in late‐stage colorectal cancer and associated
Externí odkaz:
https://doaj.org/article/92870627dcd54d3d9dae022c4ff54fd6