Zobrazeno 1 - 10
of 468
pro vyhledávání: '"Qun S"'
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 3, Pp 123-135 (2021)
Abstract Mitochondria‐associated membranes (MAMs) are essential to mitochondria. This study was to determine whether endotoxemia rearranges MAMs in the heart, and whether Beclin‐1 regulates this process. Wild‐type mice and mice with a cardiac
Externí odkaz:
https://doaj.org/article/937b921ecda343b88c4418525bb13a66
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
ObjectiveWe previously demonstrated that promoting Beclin-1–dependent autophagy is cardiac protective during endotoxemia shock, suggesting that autophagy-based approaches may become a promising therapeutic strategy for sepsis. In this study, we app
Externí odkaz:
https://doaj.org/article/a3c9a9bf7ed44cc4a78879b7a3c1cd2c
Publikováno v:
Cells, Vol 8, Iss 2, p 141 (2019)
Sepsis is a leading cause of death in intensive care units, and cardiac dysfunction is an identified serious component of the multi-organ failure associated with this critical condition. This review summarized the current discoveries and hypotheses o
Externí odkaz:
https://doaj.org/article/87a85a41f10440ca9eb215edf4f9fe3a
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3002 (2018)
Ghrelin via its receptor, the growth hormone secretagogue receptor (GHS-R), increases food intake and adiposity. The tissue-specific functions of GHS-R in peripheral tissues are mostly unknown. We previously reported that while GHS-R expression is ve
Externí odkaz:
https://doaj.org/article/50913818d6e542c49d31682961e867e3
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139416 (2015)
We have previously shown that mitochondria-targeted vitamin E (Mito-Vit-E), a mtROS specific antioxidant, improves cardiac performance and attenuates inflammation in a pneumonia-related sepsis model. In this study, we applied the same approaches to d
Externí odkaz:
https://doaj.org/article/945efe9d699e4bb8b46127cab21176e9
Autor:
Qun S Zang, Bobbie Martinez, Xiao Yao, David L Maass, Lisha Ma, Steven E Wolf, Joseph P Minei
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43424 (2012)
Our previous research demonstrated that sepsis produces mitochondrial dysfunction with increased mitochondrial oxidative stress in the heart. The present study investigated the role of mitochondria-localized signaling molecules, tyrosine kinase Src a
Externí odkaz:
https://doaj.org/article/5697fbc1edde491abb6ebdbc5a68a638
Akademický článek
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Publikováno v:
Journal of Rock Mechanics and Geotechnical Engineering, Vol 16, Iss 10, Pp 4004-4016 (2024)
The geometric properties of fracture surfaces significantly influence shear-seepage in rock fractures, introducing complexities to fracture modelling. The present study focuses on the hydro-mechanical behaviours of rough rock fractures during shear-s
Externí odkaz:
https://doaj.org/article/c93f8bba91794a3f9fd61d95a3190377
Autor:
Lan Feng, Qun Shi, Shujuan Wang, Ye Zhao, Haiyan Wu, Lei Wei, Qing Hao, Zhaojun Cui, Lin Wang, Jing Zhang, Dan Zhang, Xinxin Zhan, Jingwen Jiang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Objective Immune checkpoint inhibitor (ICI) therapy activates the immune system to recognize and eliminate cancer cells that have escaped surveillance. This study aimed to compare the treatment outcome of advanced and recurrent cervical canc
Externí odkaz:
https://doaj.org/article/9d1af354234747b58713f43450b35b5f
Akademický článek
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