NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor.

Autor: Rasmussen KK; Biological Chemistry, Department of Chemistry, University of Copenhagen, Copenhagen, Denmark. kkr@chem.ku.dk.; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark. kkr@chem.ku.dk.; Structural Biology and NMR Laboratory, Department of Biology, University of Copenhagen, Copenhagen, Denmark. kkr@chem.ku.dk., Falkesgaard MH; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Winther M; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Roed NK; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Quistgaard CL; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Teisen MN; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Edslev SM; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Petersen DL; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Aljubouri A; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Christensen C; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Thulstrup PW; Biological Chemistry, Department of Chemistry, University of Copenhagen, Copenhagen, Denmark., Lo Leggio L; Biological Chemistry, Department of Chemistry, University of Copenhagen, Copenhagen, Denmark., Teilum K; Structural Biology and NMR Laboratory, Department of Biology, University of Copenhagen, Copenhagen, Denmark., Walmod PS; Laboratory of Neural Plasticity, Department of Neuroscience and Pharmacology, University of Copenhagen, Copenhagen, Denmark.

Publikováno v: Scientific reports [Sci Rep] 2018 Jun 12; Vol. 8 (1), pp. 8957. Date of Electronic Publication: 2018 Jun 12.

Deficiency in the neural cell adhesion molecule 2 (NCAM2) reduces axonal levels of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1), affects axonal organization in the hippocampus, and leads to behavioral deficits.

Autor: Sah, Saroj, Keable, Ryan, Pfundstein, Grant, Clemens, Kelly J, Begg, Denovan, Schachner, Melitta, Leshchyns'ka, Iryna, Sytnyk, Vladimir

Publikováno v: Cerebral Cortex; 9/15/2023, Vol. 33 Issue 18, p10047-10065, 19p

NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3.

Autor: Parcerisas, Antoni, Pujadas, Lluís, Ortega-Gascó, Alba, Perelló-Amorós, Bartomeu, Viais, Ricardo, Hino, Keiko, Figueiro-Silva, Joana, Torre, Anna La, Trullás, Ramón, Simó, Sergi, Lüders, Jens, Soriano, Eduardo

Publikováno v: Cerebral Cortex; Jun2020, Vol. 30 Issue 6, p3781-3799, 19p