Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Quinton M, Dowling"'
Autor:
Quinton M. Dowling, Hannah E. Volkman, Elizabeth E. Gray, Sergey Ovchinnikov, Stephanie Cambier, Asim K. Bera, Banumathi Sankaran, Max R. Johnson, Matthew J. Bick, Alex Kang, Daniel B. Stetson, Neil P. King
Publikováno v:
Nature Structural & Molecular Biology. 30:72-80
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::327402f7257c88d20de19eff584d1a8d
https://doi.org/10.1038/s41594-022-00862-z
https://doi.org/10.1038/s41594-022-00862-z
Autor:
Quinton M, Dowling, Hannah E, Volkman, Elizabeth E, Gray, Sergey, Ovchinnikov, Stephanie, Cambier, Asim K, Bera, Banumathi, Sankaran, Max R, Johnson, Matthew J, Bick, Alex, Kang, Daniel B, Stetson, Neil P, King
Publikováno v:
Nature structuralmolecular biology.
Cyclic GMP-AMP synthase (cGAS) is a pattern recognition receptor critical for the innate immune response to intracellular pathogens, DNA damage, tumorigenesis and senescence. Binding to double-stranded DNA (dsDNA) induces conformational changes in cG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29cf47701e3c50b5b91036a7ead465f1
https://pubmed.ncbi.nlm.nih.gov/36593311
https://pubmed.ncbi.nlm.nih.gov/36593311
Autor:
Dawn M. Fedor, Quinton M. Dowling, Sylvain Cloutier, Sarah C. Parker, Michelle Archer, Lucien Barnes, Ryan M. Kramer, Thomas S. Vedvick, Simon Williams, Christopher B. Fox
Publikováno v:
AAPS PharmSciTech. 18:2077-2084
Although substantial effort has been made in the development of next-generation recombinant vaccine systems, maintenance of a cold chain is still typically required and remains a critical challenge in effective vaccine distribution. The ability to en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aef1138a9ec814550a1088847a33be3
https://doi.org/10.1208/s12249-016-0688-7
https://doi.org/10.1208/s12249-016-0688-7
Autor:
Christopher B. Fox, Quinton M. Dowling, Michelle Archer, Dawn M. Fedor, Po-Wei D. Huang, Alicia M. Schwartz, Natasha Dubois Cauwelaert, Thomas S. Vedvick, Elyse A. Beebe, Mark T. Orr, Ryan M. Kramer
Publikováno v:
International Journal of Nanomedicine
Ryan M Kramer, Michelle C Archer, Mark T Orr, Natasha Dubois Cauwelaert, Elyse A Beebe, Po-wei D Huang, Quinton M Dowling, Alicia M Schwartz, Dawn M Fedor, Thomas S Vedvick, Christopher B Fox Infectious Disease Research Institute, Seattle, WA, USA Ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4fba7f06d2f51415408295b031d995
https://pubmed.ncbi.nlm.nih.gov/29983563
https://pubmed.ncbi.nlm.nih.gov/29983563
Autor:
Quinton M. Dowling, Alicia M. Schwartz, Christopher B. Fox, Thomas S. Vedvick, Ryan M. Kramer
Publikováno v:
Journal of Pharmaceutical Sciences. 104:768-774
Aluminum salts have a long history as safe and effective vaccine adjuvants. In addition, aluminum salts have high adsorptive capacities for vaccine antigens and adjuvant molecules, for example, Toll-like receptor 4 (TLR4) agonists. However, the physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da6ed2d6d6052fb0b022f49555678aa
https://doi.org/10.1002/jps.24180
https://doi.org/10.1002/jps.24180
Autor:
Rhea N. Coler, Christopher B. Fox, Quinton M. Dowling, Mark T. Orr, John D. Laurance, Steven G. Reed, Anthony L. Desbien, Thomas S. Vedvick, Ryan M. Kramer, Lucien Barnes, Elyse A. Beebe
Publikováno v:
Journal of Controlled Release. 177:20-26
Next-generation rationally-designed vaccine adjuvants represent a significant breakthrough to enable development of vaccines against challenging diseases including tuberculosis, HIV, and malaria. New vaccine candidates often require maintenance of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3051de4a6155463c5fbb2a1edf106858
https://doi.org/10.1016/j.jconrel.2013.12.025
https://doi.org/10.1016/j.jconrel.2013.12.025
Autor:
Jeff Guderian, James Chesko, Christopher B. Fox, Magdalini Moutaftsi, Quinton M. Dowling, Thomas S. Vedvick, Ryan M. Kramer, Sandra J. Sivananthan
Publikováno v:
Journal of Pharmaceutical Sciences. 103:879-889
Activity of adjuvanted vaccines is difficult to predict in vitro and in vivo. The wide compositional and conformational range of formulated adjuvants, from aluminum salts to oil-in-water emulsions, makes comparisons between physicochemical and immuno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7f1d619766951793a2a3635d569852
https://doi.org/10.1002/jps.23868
https://doi.org/10.1002/jps.23868
Autor:
Quinton M, Dowling, Ryan M, Kramer
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1494
Fourier transform infrared (FTIR) spectroscopy is widely used in the pharmaceutical industry for process monitoring, compositional quantification, and characterization of critical quality attributes in complex mixtures. Advantages over other spectros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1d208851143190fc71ad552f0f33c6d
https://pubmed.ncbi.nlm.nih.gov/27718199
https://pubmed.ncbi.nlm.nih.gov/27718199
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1494
Dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) are two orthogonal and complementary methods of measuring size of particles in a sample. These technologies use the theory of Brownian motion by analyzing the random changes of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb6a3d6d5753ee95a39d1c0d51fb16dd
https://pubmed.ncbi.nlm.nih.gov/27718198
https://pubmed.ncbi.nlm.nih.gov/27718198
Publikováno v:
Methods in Molecular Biology ISBN: 9781493964437
Dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA) are two orthogonal and complementary methods of measuring size of particles in a sample. These technologies use the theory of Brownian motion by analyzing the random changes of l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41653ce12918784de42b244b6034afb9
https://doi.org/10.1007/978-1-4939-6445-1_17
https://doi.org/10.1007/978-1-4939-6445-1_17
