Výsledky vyhledávání - "Quinten Remijsen"

Drug–drug interactions between immunosuppressants and antidiabetic drugs in the treatment of post-transplant diabetes mellitus

Autor: Quinten Remijsen, Thomas Vanhove, Pieter Gillard, Dirk Kuypers

Publikováno v: Transplantation Reviews. 31:69-77

Post-transplant diabetes mellitus is a frequent complication of solid organ transplantation that generally requires treatment with lifestyle interventions and antidiabetic medication. A number of demonstrated and potential pharmacokinetic drug-drug i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c425d913ca623090560f67c505553993
https://doi.org/10.1016/j.trre.2016.09.001

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Neutrophil extracellular trap cell death requires both autophagy and superoxide generation

Autor: Riet De Rycke, Ellen Wirawan, Quinten Remijsen, Eef Parthoens, Jean Willems, Samuel Noppen, Michel Delforge, Peter Vandenabeele, Tom Vanden Berghe, Bob Asselbergh

Publikováno v: Cell Research; Vol 21

Neutrophil extracellular traps (NETs) are extracellular chromatin structures that can trap and degrade microbes. They arise from neutrophils that have activated a cell death program called NET cell death, or NETosis. Activation of NETosis has been sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c790e693866a420c8d0ca8efab49e7f
https://doi.org/10.1038/cr.2010.150

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Parabutoporin, a cationic amphipathic peptide from scorpion venom: Much more than an antibiotic

Autor: Jean Willems, Fons Verdonck, Quinten Remijsen

Publikováno v: Toxicon. 55:180-185

Parabutoporin (PP) from the South African scorpion Parabuthus schlechteri is a 45-mer lysine-rich and cysteine-free peptide. At micromolar concentrations it has antimicrobial effects against G+ and G- bacteria and is antifungal as well. However, at s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b615000b308a51c61132b8a130a19e8f
https://doi.org/10.1016/j.toxicon.2009.10.027

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Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt

Autor: Eef Parthoens, Tom Vanden Berghe, Bob Asselbergh, Peter Vandenabeele, Quinten Remijsen, Jean Willems

Publikováno v: Journal of Leukocyte Biology; Vol 85

Neutrophil cell death plays a crucial role in neutrophil homeostasis and the resolution of inflammation. The superoxide-producing NADPH oxidase is involved in pathogen degradation and subsequent activation of cell death programs. Neutrophils from pat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970e0944c145404fb2afcf52333e4969
https://doi.org/10.1189/jlb.0908525

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Antioxidant potential of CORM-A1 and resveratrol during TNF-α/cycloheximide-induced oxidative stress and apoptosis in murine intestinal epithelial MODE-K cells

Autor: Roberto Motterlini, Georges Leclercq, Peter Vandenabeele, Vera Goossens, Dinesh Babu, Romain Lefebvre, Quinten Remijsen

Publikováno v: Toxicology and applied pharmacology. 288(2)

Targeting excessive production of reactive oxygen species (ROS) could be an effective therapeutic strategy to prevent oxidative stress-associated gastrointestinal inflammation. NADPH oxidase (NOX) and mitochondrial complexes (I and II) are the major

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6dac2423a3fdd2b6c83bc7d8a37e722
https://pubmed.ncbi.nlm.nih.gov/26187750

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Escherichia coli induces bovine neutrophil cell death independent from caspase-3/-7/-1, but with phosphatidylserine exposure prior to membrane rupture

Autor: Christopher J. Guérin, Peter Vandenabeele, Sofie Notebaert, Filip Boyen, Dieter Demon, Evelyne Meyer, Koen Breyne, Quinten Remijsen, Kristel Demeyere

Publikováno v: VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY
Veterinary Immunology and Immunopathology; Vol 153

Neutrophils are essential for the innate immune response against bacterial pathogens and play a key role during the early phases of infection, including mastitis and endometritis in cows. When directly challenged with bacteria, neutrophils undergo ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373d619d13a80ddeb7585feaccbbf4c0
https://hdl.handle.net/1854/LU-4099308

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Reconstitution of protection against Aspergillus infection in chronic granulomatous disease (CGD)

Autor: Jean Willems, Peter Vandenabeele, Quinten Remijsen, Taco W. Kuijpers

Publikováno v: Blood, 114(16). American Society of Hematology

Chronic granulomatous disease (CGD) patients have impaired nicotinamide adenine dinucleotide phosphate (NADPH) oxidase function, resulting in poor antimicrobial activity of neutrophils, including the inability to generate neutrophil extracellular tra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c421c09154c842272b20212c6de9387f
https://lirias.kuleuven.be/handle/123456789/247735

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Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis

Autor: Mathieu J.M. Bertrand, Nozomi Takahashi, Peter Vandenabeele, Vera Goossens, C. Van den Haute, Tom Vanden Berghe, Quinten Remijsen, Ria Roelandt, Yves Dondelinger, Sasker Grootjans, Nele Vanlangenakker, Veerle Baekelandt, Inge Bruggeman, Amanda Gonçalves

Publikováno v: Cell Death & Disease
CELL DEATH & DISEASE

In human cells, the RIPK1-RIPK3-MLKL-PGAM5-Drp1 axis drives tumor necrosis factor (TNF)-induced necroptosis through mitochondrial fission, but whether this pathway is conserved among mammals is not known. To answer this question, we analyzed the pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c38317c70254050ead0990838fb2f20a
http://europepmc.org/articles/PMC4040672

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