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Toll-like receptor orchestrates a tumor suppressor response in non-small cell lung cancer

Autor: Millar, Fraser, Pennycuick, Adam, Muir, Morwenna, Quintanilla, Andrea, Hari, Priya, Freyer, Elisabeth, Gautier, Philippe, Meynert, Alison M, Grimes, Graeme R, Salomo Coll, Carla, Zdral, Sofia, Victorelli, Stella, Teixeira, Vitor H., Connolly, John, Passos, Joao F, Ros, Marian A, Wallace, William, Frame, Margaret C, Sims, Andrew H, Boulter, Luke, Janes, Sam M, Wilkinson, Simon, Acosta, Juan Carlos

Publikováno v: Millar, F, Pennycuick, A, Muir, M, Quintanilla, A, Hari, P, Freyer, E, Gautier, P, Meynert, A M, Grimes, G R, Salomo Coll, C, Zdral, S, Victorelli, S, Teixeira, V H, Connolly, J, Passos, J F, Ros, M A, Wallace, W, Frame, M C, Sims, A H, Boulter, L, Janes, S M, Wilkinson, S & Acosta, J C 2022, ' Toll-like receptor orchestrates a tumor suppressor response in non-small cell lung cancer ', Cell Reports . https://doi.org/10.1016/j.celrep.2022.111596

Targeting early-stage lung cancer is vital to improve survival. Yet, the mechanisms and components of the early tumor suppressor response in lung cancer are not well understood. In this report we study the role of TLR2, a regulator of oncogene-induce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::258cd64b70b9116c67b233424ea571ce
https://www.pure.ed.ac.uk/ws/files/308129435/Toll_like_receptor_orchestrates_a_tumor_suppressor_response_in_non_small_cell_lung_cancer_published_pdf.pdf

Estudio de alternativas para la eliminación biológica de materia orgánica y nutrientes para la población de Cusco (Perú)

Autor: Rivas Quintanilla, Andrea

Publikováno v: RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
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[ES] El presente trabajo fin de master evalúa diferentes alternativas y propone la más eficiente considerando porcentajes de eliminación tanto de materia orgánica como de nutrientes así también como los costos de construcción y mantenimiento d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::2c2ad46586f31dc3cd8044e1ef12dfdd
http://hdl.handle.net/10251/160136

Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence

Autor: Fernández-Duran, Irene, Quintanilla, Andrea, Tarrats, Núria, Birch, Jodie, Hari, Priya, Millar, Fraser R., Lagnado, Anthony B., Smer-Barreto, Vanessa, Muir, Morwenna, Brunton, Valerie G., Passos, João F., Acosta, Juan Carlos

Publikováno v: Cell Death and Differentiation; June 2022, Vol. 29 Issue: 6 p1267-1282, 16p

PHD3 regulates p53 protein stability by hydroxylating Proline 359

Autor: Rodriguez, Javier, Herrero, Ana, Li, Shuijie, Rauch, Nora, Quintanilla, Andrea, Wynne, Kieran, Krstic, Aleksandar, Acosta, Juan Carlos, Taylor, Cormac, Schlisio, Susanne, von Kriegsheim, Alex

Publikováno v: Rodriguez, J, Herrero, A, Li, S, Rauch, N, Quintanilla, A, Wynne, K, Krstic, A, Acosta, J C, Taylor, C, Schlisio, S & von Kriegsheim, A 2018, ' PHD3 regulates p53 protein stability by hydroxylating Proline 359 ', Cell Reports . https://doi.org/10.1016/j.celrep.2018.06.108
Cell Reports

Summary Cellular p53 protein levels are regulated by a ubiquitination/de-ubiquitination cycle that can target the protein for proteasomal destruction. The ubiquitination reaction is catalyzed by a multitude of ligases, whereas the removal of ubiquiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d8ee9a6ebb2a5e51deefcb8a7f424c64
https://hdl.handle.net/20.500.11820/140f6b18-8d00-4012-83c6-da3b42ec108b