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pro vyhledávání: '"Quinn R. Kirkpatrick"'
Autor:
Kathryn M. Lemberg, Rana Rais, Ranjeet Prasad Dash, Kateřina Novotná, Jesse Alt, Pavel Majer, Barbara S. Slusher, Lukáš Tenora, Alexandra J. Gadiano, Quinn R. Kirkpatrick, Jenny Lam, Vijayabhaskar Veeravalli
Publikováno v:
J Med Chem
6-Diazo-5-oxo-l-norleucine (DON) is a glutamine antagonist with robust anticancer efficacy; however, its therapeutic potential was hampered by its biodistribution and toxicity to normal tissues, specifically gastrointestinal (GI) tissues. To circumve