Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Quinn P, Peterson"'
Autor:
Fatmah R. Alsereidi, Zenith Khashim, Hezlin Marzook, Ahmed M. Al-Rawi, Tiana Salomon, Mahra K. Almansoori, Moustafa M. Madkour, Ahmed Mohamed Hamam, Mahmoud M. Ramadan, Quinn P. Peterson, Mohamed A. Saleh
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-22 (2024)
Abstract Abstract Dapagliflozin (DAPA), a sodium-glucose cotransporter 2 (SGLT2) inhibitor, is well-recognized for its therapeutic benefits in type 2 diabetes (T2D) and cardiovascular diseases. In this comprehensive in vitro study, we investigated DA
Externí odkaz:
https://doaj.org/article/66efeddb86da4093bfbe280b78a341bb
Autor:
Kihak Gwon, Ether Dharmesh, Kianna M. Nguyen, Anna Marie R. Schornack, Jose M. de Hoyos-Vega, Hakan Ceylan, Gulnaz Stybayeva, Quinn P. Peterson, Alexander Revzin
Publikováno v:
Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Human pluripotent stem cells (hPSCs) represent an excellent cell source for regenerative medicine and tissue engineering applications. However, there remains a need for robust and scalable differentiation of stem cells into functional adult
Externí odkaz:
https://doaj.org/article/8f3caee6592e456e81bd4c902b791461
Autor:
Kihak Gwon, Hye Jin Hong, Alan M. Gonzalez-Suarez, Michael Q. Slama, Daheui Choi, Jinkee Hong, Harihara Baskaran, Gulnaz Stybayeva, Quinn P. Peterson, Alexander Revzin
Publikováno v:
Bioactive Materials, Vol 15, Iss , Pp 1-14 (2022)
Human pluripotent stem cells (hPSC) hold considerable promise as a source of adult cells for treatment of diseases ranging from diabetes to liver failure. Some of the challenges that limit the clinical/translational impact of hPSCs are high cost and
Externí odkaz:
https://doaj.org/article/82e304db50db4772875bb07418f55833
Autor:
Pouria Fattahi, Jose M. de Hoyos-Vega, Jong Hoon Choi, Caden D. Duffy, Alan M. Gonzalez-Suarez, Yuji Ishida, Kianna M. Nguyen, Kihak Gwon, Quinn P. Peterson, Takeshi Saito, Gulnaz Stybayeva, Alexander Revzin
Publikováno v:
Cells, Vol 12, Iss 15, p 1982 (2023)
Human pluripotent stem cells (hPSCs) are capable of unlimited proliferation and can undergo differentiation to give rise to cells and tissues of the three primary germ layers. While directing lineage selection of hPSCs has been an active area of rese
Externí odkaz:
https://doaj.org/article/a37baaa26ed144c583c718d6c96e880b
Autor:
Pouria Fattahi, Ali Rahimian, Michael Q. Slama, Kihak Gwon, Alan M. Gonzalez-Suarez, Jadon Wolf, Harihara Baskaran, Caden D. Duffy, Gulnaz Stybayeva, Quinn P. Peterson, Alexander Revzin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Cellular therapies based on human pluripotent stem cells (hPSCs) offer considerable promise for treating numerous diseases including diabetes and end stage liver failure. Stem cell spheroids may be cultured in stirred bioreactors to scale up
Externí odkaz:
https://doaj.org/article/53e0a7662aba4e918a6dcc5423f60520
Autor:
Quinn P. Peterson, Adrian Veres, Lihua Chen, Michael Q. Slama, Jennifer H. R. Kenty, Shaimaa Hassoun, Matthew R. Brown, Haiqiang Dou, Caden D. Duffy, Quan Zhou, Aleksey V. Matveyenko, Björn Tyrberg, Maria Sörhede-Winzell, Patrik Rorsman, Douglas A. Melton
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Deriving functional pancreatic cell types from human stem cells may have important clinical applications. Building on previous work, here the authors generate stem cell-derived alpha cells via a polyhormonal intermediate, which have a gene expression
Externí odkaz:
https://doaj.org/article/6faab0e582834b4a8aca6528596abca2
Autor:
Alessandra Rigamonti, Giuliana G. Repetti, Chicheng Sun, Feodor D. Price, Danielle C. Reny, Francesca Rapino, Karen Weisinger, Chen Benkler, Quinn P. Peterson, Lance S. Davidow, Emil M. Hansson, Lee L. Rubin
Publikováno v:
Stem Cell Reports, Vol 6, Iss 6, Pp 993-1008 (2016)
Summary: Human pluripotent stem cells (hPSCs) offer a renewable source of cells that can be expanded indefinitely and differentiated into virtually any type of cell in the human body, including neurons. This opens up unprecedented possibilities to st
Externí odkaz:
https://doaj.org/article/e6b00698c1684cd49a830854f122ca4d
Autor:
Li Zhan, Joseph Sushil Rao, Nikhil Sethia, Michael Q. Slama, Zonghu Han, Diane Tobolt, Michael Etheridge, Quinn P. Peterson, Cari S. Dutcher, John C. Bischof, Erik B. Finger
Publikováno v:
Nature Medicine. 28:798-808
Pancreatic islet transplantation can cure diabetes but requires accessible, high-quality islets in sufficient quantities. Cryopreservation could solve islet supply chain challenges by enabling quality-controlled banking and pooling of donor islets. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f0046a90c232cffea5a08a4a42aac32
https://doi.org/10.1038/s41591-022-01718-1
https://doi.org/10.1038/s41591-022-01718-1
Data from Discovery and Canine Preclinical Assessment of a Nontoxic Procaspase-3–Activating Compound
Autor:
Timothy M. Fan, Paul J. Hergenrother, Levent Dirikolu, Joanna M. Schmit, Dewey Kim, Diana C. West, Chris J. Novotny, Danny C. Hsu, Quinn P. Peterson
A critical event in the apoptotic cascade is the proteolytic activation of procaspases to active caspases. The caspase autoactivating compound PAC-1 induces cancer cell apoptosis and exhibits antitumor activity in murine xenograft models when adminis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4da4676de1260cceb60939b1883cd170
https://doi.org/10.1158/0008-5472.c.6500739
https://doi.org/10.1158/0008-5472.c.6500739
Autor:
Timothy M. Fan, Paul J. Hergenrother, Levent Dirikolu, Joanna M. Schmit, Dewey Kim, Diana C. West, Chris J. Novotny, Danny C. Hsu, Quinn P. Peterson
Supplementary Methods and Materials, Figure 1, Tables 1-2 from Discovery and Canine Preclinical Assessment of a Nontoxic Procaspase-3–Activating Compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ab42579487dd63ef7dd02eb43a91e0
https://doi.org/10.1158/0008-5472.22383996
https://doi.org/10.1158/0008-5472.22383996