Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Quinn H, Hogan"'
Autor:
Brandon Itson-Zoske, Seung Min Shin, Hao Xu, Chensheng Qiu, Fan Fan, Quinn H. Hogan, Hongwei Yu
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-15 (2022)
Abstract Background Peripheral and central nociceptive sensitization is a critical pathogenetic component in osteoarthritis (OA) chronic pain. T-type calcium channel 3.2 (CaV3.2) regulates neuronal excitability and plays important roles in pain proce
Externí odkaz:
https://doaj.org/article/287fb8b52b0845bfbe9f61abfe27e12d
Publikováno v:
Neurobiology of Pain, Vol 12, Iss , Pp 100104- (2022)
There is growing literature supporting cannabinoids as a potential therapeutic for pain conditions. The development of chronic pain has been associated with reduced concentrations of the endogenous cannabinoid anandamide (AEA) in the midbrain dorsal
Externí odkaz:
https://doaj.org/article/acb27cf68b8b445fbb982aa72b884d11
Autor:
Yin Feng, Keguo Li, Elizabeth Roth, Dongman Chao, Christina M. Mecca, Quinn H. Hogan, Christopher Pawela, Wai-Meng Kwok, Amadou K. S. Camara, Bin Pan
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
A major hurdle preventing effective interventions for patients with mild traumatic brain injury (mTBI) is the lack of known mechanisms for the long-term cognitive impairment that follows mTBI. The closed head impact model of repeated engineered rotat
Externí odkaz:
https://doaj.org/article/8d671e316ce44557b8d32cb7c9eabd47
Autor:
Katherine Sherman, Victoria Woyach, James C. Eisenach, Francis A. Hopp, Freddy Cao, Quinn H. Hogan, Caron Dean
Publikováno v:
Neurobiology of Pain, Vol 10, Iss , Pp 100069- (2021)
The genesis of neuropathic pain is complex, as sensory abnormalities may differ between patients with different or similar etiologies, suggesting mechanistic heterogeneity, a concept that is largely unexplored. Yet, data are usually grouped for analy
Externí odkaz:
https://doaj.org/article/82906cf37ae14ebc92a32a7815a13e4e
Autor:
Victoria Woyach, Katherine Sherman, Cecilia J. Hillard, Francis A. Hopp, Quinn H. Hogan, Caron Dean
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 323(5)
The complexity of neuropathic pain and its associated comorbidities, including dysautonomia, make it difficult to treat. Overlap of anatomical regions and pharmacology of sympathosensory systems in the central nervous system (CNS) provide targets for
Autor:
Hongwei Yu, Seung Min Shin, Fei Wang, Hao Xu, Hongfei Xiang, Yongsong Cai, Brandon Itson-Zoske, Quinn H. Hogan
Publikováno v:
PAIN Reports, Vol 4, Iss 1, p e703 (2019)
Abstract. Introduction:. Tmem100 modulates interactions between TRPA1 and TRPV1. The cell specificity of Tmem100 expression in dorsal root ganglia (DRGs) is not well defined, nor is the effect of peripheral nerve injury on Tmem100 expression. Objecti
Externí odkaz:
https://doaj.org/article/848386c975cb484e9c9bcd114352acfa
Autor:
Tyler B. Waltz, Dongman Chao, Eve K. Prodoehl, Vanessa L. Ehlers, Bhavya S. Dharanikota, Nancy M. Dahms, Elena Isaeva, Quinn H. Hogan, Bin Pan, Cheryl L. Stucky
Publikováno v:
bioRxiv
Patients with Fabry disease suffer from chronic debilitating pain and peripheral sensory neuropathy with minimal treatment options, but the cellular drivers of this pain are unknown. Here, we propose a novel mechanism by which altered signaling betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b924350ad5a1fd2538f69f704c65c60d
https://doi.org/10.1101/2023.05.26.542493
https://doi.org/10.1101/2023.05.26.542493
Autor:
Fan Fan, Brandon Itson-Zoske, Hongwei Yu, Cheryl L. Stucky, Seung Min Shin, Francie Moehring, Quinn H. Hogan
Publikováno v:
Pain
Piezo2 mechanotransduction channel is a crucial mediator of sensory neurons for sensing and transducing touch, vibration, and proprioception. We here characterized Piezo2 expression and cell specificity in rat peripheral sensory pathway using a valid
Autor:
Seung Min Shin, Brandon Itson-Zoske, Fan Fan, Uarda Gani, Mahmudur Rahman, Quinn H. Hogan, Hongwei Yu
Publikováno v:
Molecular Pain. 19:174480692311743
Here, we present evidence showing Piezo1 protein expression in the primary sensory neurons (PSNs) and non-neuronal cells of rat peripheral nervous system. Using a knockdown/knockout validated antibody, we detected Piezo1 immunoreactivity (IR) in ∼6
Autor:
Yu Ting Lin, Shao Ming Wang, Katherine L. Wilson, Quinn H. Hogan, Hsiang En Wu, Tsung-Ping Su, Nino Goguadze, Bin Pan, Yoki Nakamura, Yuko Yasui, Tzu Yun Wang, Yuriko Kimura
Publikováno v:
Molecular Neurobiology
Mol Neurobiol
Mol Neurobiol
Sigma-1 receptors (Sig-1Rs) are endoplasmic reticulum (ER) chaperones implicated in neuropathic pain. Here we examine if the Sig-1R may relate to neuropathic pain at the level of dorsal root ganglia (DRG). We focus on the neuronal excitability of DRG