Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Quinn A. Best"'
Autor:
Quinn A. Best, Richard A. Haack, Kerry M. Swift, Brian M. Bax, Sergey Y. Tetin, Stefan J. Hershberger
Publikováno v:
Luminescence. 36:1097-1106
Multicolor chemiluminescent acridinium derivatives were synthesized by attaching various common fluorophores to the N10 -acridinium position through a piperazine linker. Triggering of each acridinium derivative using alkaline hydrogen peroxide result
Aqueous NMR Signal Enhancement by Reversible Exchange in a Single Step Using Water-Soluble Catalysts
Autor:
Kevin W. Waddell, Fan Shi, Eduard Y. Chekmenev, Roman V. Shchepin, Kirsten A. Groome, Greg Zimay, Milton L. Truong, Quinn A. Best, Aaron M. Coffey, Boyd M. Goodson, Ping He
Publikováno v:
The Journal of Physical Chemistry. C, Nanomaterials and Interfaces
Two synthetic strategies are investigated for the preparation of water-soluble iridium-based catalysts for NMR signal amplification by reversible exchange (SABRE). In one approach, PEGylation of a variant N-heterocyclic carbene provided a novel catal
Publikováno v:
Tetrahedron Letters. 61:152332
Heterobifunctional compounds are of considerable interest in convergent synthesis strategies as well as in the labeling/tagging of biological molecules. Herein is described a synthetic strategy to functionalize sulfonic acids in the presence of carbo
Publikováno v:
ACS Chemical Biology. 11:231-240
We successfully synthesized a fluorescent probe capable of detecting the cancer-associatedquinoneoxidoreductase isozyme-1 within human cells, based on results from an investigation of the stability of various rhodamines and seminaphthorhodamines towa
Autor:
Chuangjun Liu, Quinn A. Best, Matthew E. McCarroll, Brian Suarez, Jack Pertile, Colleen N. Scott
Publikováno v:
Journal of Fluorescence. 25:231-237
A series of fluorescent pH probes based on the spiro-cyclic rhodamine core, aminomethylrhodamines (AMR), was synthesized and the effect of cycloalkane ring size on the acid/base properties of the AMR system was explored. The study involved a series o
Autor:
Kevin W. Waddell, Eduard Y. Chekmenev, Roman V. Shchepin, Kirill V. Kovtunov, Milton L. Truong, Danila A. Barskiy, Boyd M. Goodson, Kirsten A. Groome, Aaron M. Coffey, Ping He, Fan Shi, Quinn A. Best, Igor V. Koptyug
Publikováno v:
ChemPhysChem. 15:4100-4107
By using 5.75 and 47.5 mT nuclear magnetic resonance (NMR) spectroscopy, up to 10(5)-fold sensitivity enhancement through signal amplification by reversible exchange (SABRE) was enabled, and subsecond temporal resolution was used to monitor an exchan
Autor:
Danila A. Barskiy, Igor V. Koptyug, Kevin W. Waddell, Eduard Y. Chekmenev, Boyd M. Goodson, Fan Shi, Kirsten A. Groome, Ping He, Quinn A. Best, Kirill V. Kovtunov, Roman V. Shchepin, Aaron M. Coffey
Publikováno v:
Analytical Chemistry
We demonstrate the feasibility of microscale molecular imaging using hyperpolarized proton and carbon-13 MRI contrast media and low-field (47.5 mT) preclinical scale (38 mm i.d.) 2D magnetic resonance imaging (MRI). Hyperpolarized proton images with
Autor:
Aaron M. Coffey, Igor V. Koptyug, Eduard Y. Chekmenev, Boyd M. Goodson, Roman V. Shchepin, Ping He, Danila A. Barskiy, Fan Shi, Quinn A. Best, Kevin W. Waddell, Kirill V. Kovtunov, Kirsten A. Groome
Publikováno v:
ResearcherID
Journal of the American Chemical Society
Journal of the American Chemical Society
(1)H NMR signal amplification by reversible exchange (SABRE) was observed for pyridine and pyridine-d5 at 9.4 T, a field that is orders of magnitude higher than what is typically utilized to achieve the conventional low-field SABRE effect. In additio
Publikováno v:
The Journal of Organic Chemistry. 78:10134-10143
A series of pH dependent rhodamine analogues possessing an anilino-methyl moiety was developed and shown to exhibit a unique photophysical response to pH. These anilinomethylrhodamines (AnMR) maintain a colorless, nonfluorescent spirocyclic structure
Publikováno v:
Journal of the American Chemical Society. 135:13365-13370
We report the synthesis and characterization of a fluorescent probe (Hypo-SiF) designed for the detection of hypochlorous acid (HOCl) using a silicon analogue of fluorescein (SiF). The probe is regulated in an "off-on" fashion by a highly selective t