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pro vyhledávání: '"Quinaprilat"'
Akademický článek
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Autor:
Emilia Konarzewska, Marzena Wojewodzka-Zelezniakowicz, Jerzy Robert Ladny, Ewa Chabielska, Wioleta Kisiel, Anna Gromotowicz-Poplawska, Janusz Szemraj
Publikováno v:
Journal of the Renin-Angiotensin-Aldosterone System: JRAAS
Journal of the Renin-Angiotensin-Aldosterone System, Vol 18 (2017)
Journal of the Renin-Angiotensin-Aldosterone System, Vol 18 (2017)
Introduction: The aim of this study was to investigate the effects of plasma and tissue angiotensin-converting enzyme inhibitors (ACE-Is) against propofol-induced endothelial dysfunction and to elucidate the involved mechanisms in vitro. Materials an
Autor:
Sigrid Mennickent, Camilo Hernández, Carola Vergara, Marta de Diego, Henry Charnock, Ricardo Godoy
Publikováno v:
Journal of Chromatographic Science. 54:1346-1351
Rapid stability-indicating LC methods for simultaneous analysis of quinapril and hydrochlorothiazide were developed, validated and compared using evaporative light scattering detection (ELSD) and diode array detection (DAD). For the separation of qui
Autor:
Pertti J. Neuvonen, Mikko T. Holmberg, Janne T. Backman, Terhi Launiainen, Aleksi Tornio, Mikko Niemi, E. Katriina Tarkiainen
Publikováno v:
British Journal of Clinical Pharmacology. 80:1131-1138
Aim The aim of the present study was to investigate the effects of the carboxylesterase 1 (CES1) c.428G > A (p.G143E, rs71647871) single nucleotide variation (SNV) on the pharmacokinetics of quinapril and enalapril in a prospective genotype panel stu
Publikováno v:
Talanta. 179
A novel electrochemiluminescence (ECL) sensor with composite consisted of silica-sol, Zinc oxide nanoparticles (ZnO NPs), polyvinylpyrrolidone (PVP) and tris(2, 2'-bipyridine) ruthenium (II) was constructed. A new method for simultaneous determinatio
Publikováno v:
Bulletin of Experimental Biology and Medicine. 152:590-594
We studied the effects of three various angiotensin converting enzyme inhibitors (enalapril, lisinopril and quinapril) on heart rhythm variability in anesthetized and immobilized rats. In all cases (except for quinapril in experiments on anesthetized
Publikováno v:
Expert Opinion on Drug Metabolism & Toxicology. 5:1337-1347
Quinaprilat is an ACE inhibitor for intravenous use especially in patients with arterial hypertension or chronic heart failure. In contrast to the oral prodrug quinapril, it has not been approved for clinical application.In this review, the pharmacok
Autor:
Ying Yu, Haodan Yuan, Jonathan Chupka, Bo Feng, Jenny Y. Zheng, Brian R. Bond, Timothy G. Heath
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 330:191-197
In humans and rats, a synergistic blood pressure reduction was observed when the fibrate gemcabene (CI-1027) was coadministered with the angiotensin-converting enzyme inhibitor quinapril. In a quinapril (3 mg/kg) pharmacokinetic rat study, there was
Publikováno v:
Journal of Molecular Structure: THEOCHEM. 869:19-28
The density functional theory (DFT) using Becke3LYP functional and the two-layered ONIOM Becke3LYP:MNDO calculations have been carried out to investigate the structural and thermodynamic properties of 29 neutral and deprotonated angiotensin-convertin
Autor:
Sagar A. Parekh, Ashutosh Pudage, Sudhir S Kamat, Santosh S. Joshi, Vikas V. Vaidya, Noel A. Gomes
Publikováno v:
Journal of Chromatography B. 873:59-69
A rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been developed and validated for the simultaneous estimation of hydrochlorothiazide, quinapril and its metabolite quinaprilat in human plasma. After solid phas