Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Quim Peña"'
Autor:
Quim Peña, Sergi Rodríguez-Calado, A. Jalila Simaan, Mercè Capdevila, Pau Bayón, Oscar Palacios, Julia Lorenzo, Olga Iranzo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Metal-based chemotherapeutics like cisplatin are widely employed in cancer treatment. In the last years, the design of redox-active (transition) metal complexes, such as of copper (Cu), has attracted high interest as alternatives to overcome platinum
Externí odkaz:
https://doaj.org/article/2ac498bd2c4d49ca800cae2d859fa6e2
Autor:
Ilaria Biancacci, Federica De Lorenzi, Benjamin Theek, Xiangyang Bai, Jan‐Niklas May, Lorena Consolino, Maike Baues, Diana Moeckel, Felix Gremse, Saskia vonStillfried, Asmaa El Shafei, Karina Benderski, Armin Azadkhah Shalmani, Alec Wang, Jeffrey Momoh, Quim Peña, Eva Miriam Buhl, Johannes Buyel, Wim Hennink, Fabian Kiessling, Josbert Metselaar, Yang Shi, Twan Lammers
Publikováno v:
Advanced Science, Vol 9, Iss 10, Pp n/a-n/a (2022)
Abstract Cancer nanomedicines rely on the enhanced permeability and retention (EPR) effect for efficient target site accumulation. The EPR effect, however, is highly heterogeneous among different tumor types and cancer patients and its extent is expe
Externí odkaz:
https://doaj.org/article/e176678c786847e28bbd7e7799858866
Autor:
Jacopo Andreo, Romy Ettlinger, Orysia Zaremba, Quim Peña, Ulrich Lächelt, Roberto Fernández de Luis, Ralph Freund, Stefano Canossa, Evelyn Ploetz, Wei Zhu, Christian S. Diercks, Harald Gröger, Stefan Wuttke
The chemistry of metal-organic and covalent organic frameworks (MOFs and COFs) is perhaps the most diverse and inclusive among the chemical sciences, and yet it can be radically expanded by blending it with nanotechnology. The result is reticular nan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0982ac94caf73919d018c0a12586a5b
https://pub.uni-bielefeld.de/record/2962334
https://pub.uni-bielefeld.de/record/2962334
Autor:
Masoud Sadeghzadeh, Sara Sanchez Berlanga, Fabian Hertel, Alexandru Florea, Sabri Sahnoun, Alec Wang, Karolin Römhild, Jan-Niklas May, Quim Peña, Yang Shi, Josbert Metselaar, Twan Lammers, Felix Mottaghy
Publikováno v:
Nuclear Medicine and Biology. :S163-S164
Autor:
Mihael Vucur, Jiong-Wei Wang, Gert Storm, Fabian Kiessling, Federica De Lorenzi, Armin Azadkhah Shalmani, Alexandros Marios Sofias, Quim Peña, Twan Lammers, Lorena Consolino, Yang Shi
Publikováno v:
Advanced Drug Delivery Reviews, 175, 1. Elsevier
Adv Drug Deliv Rev
Advanced Drug Delivery Reviews
Adv Drug Deliv Rev
Advanced Drug Delivery Reviews
Fibrosis is a common denominator in many pathologies and crucially affects disease progression, drug delivery efficiency and therapy outcome. We here summarize therapeutic and diagnostic strategies for fibrosis targeting in atherosclerosis and cardia
Autor:
Quim, Peña, Giuseppe, Sciortino, Jean-Didier, Maréchal, Sylvain, Bertaina, A Jalila, Simaan, Julia, Lorenzo, Mercè, Capdevila, Pau, Bayón, Olga, Iranzo, Òscar, Palacios
Publikováno v:
Inorganic Chemistry
Three novel dinuclear Cu(II) complexes based on a N,N,O-chelating salphen-like ligand scaffold and bearing varying aromatic substituents (−H, −Cl, and −Br) have been synthesized and characterized. The experimental and computational data obtaine
Autor:
A. Jalila Simaan, Pau Bayón, Giuseppe Sciortino, Òscar Palacios, Olga Iranzo, Quim Peña, Julia Lorenzo, Sergi Rodríguez-Calado, Mercè Capdevila, Jean-Didier Maréchal
Publikováno v:
Journal of Inorganic Biochemistry
Journal of Inorganic Biochemistry, Elsevier, In press, 195, pp.51-60. ⟨10.1016/j.jinorgbio.2019.03.011⟩
Journal of Inorganic Biochemistry, In press, 195, pp.51-60. ⟨10.1016/j.jinorgbio.2019.03.011⟩
Journal of Inorganic Biochemistry, Elsevier, In press, 195, pp.51-60. ⟨10.1016/j.jinorgbio.2019.03.011⟩
Journal of Inorganic Biochemistry, In press, 195, pp.51-60. ⟨10.1016/j.jinorgbio.2019.03.011⟩
Reactive oxygen species (ROS) formation appears as one of the most promising pathways to induce cell death. The interesting Cu(II)/Cu(I) redox pair has been reported to biologically generate ROS and induce cell damage. Simple metal complexes, such as
Autor:
Marta Figueredo, Kevin Morales, Pau Bayón, Quim Peña, Antonio Rodríguez-Diéguez, Katia G. Samper, Òscar Palacios, Jordi Hernando, Julia Lorenzo, Mercè Capdevila
Two new squaramide-based platinum(II) complexes C1 and C2 have been synthesized and fully characterized. Their photoresponse has been assessed and is discussed. A remarkable enhancement in the DNA binding activity has been observed for both complexes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c144d5ebf0e1d8f984ec53cc26b7a4b
https://ddd.uab.cat/record/273779
https://ddd.uab.cat/record/273779
Autor:
Quim Peña, Alec Wang, Orysia Zaremba, Yang Shi, Hans W. Scheeren, Josbert M. Metselaar, Fabian Kiessling, Roger M. Pallares, Stefan Wuttke, Twan Lammers
Publikováno v:
Chemical Society Reviews. 51(7):2544-2582
Metal complexes are extensively used for cancer therapy. The multiple variables available for tuning (metal, ligand, and metal-ligand interaction) offer unique opportunities for drug design, and have led to a vast portfolio of metallodrugs that can d
Autor:
'Quim Peña
Publikováno v:
Alec Wang