Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Quezia B. Cass"'
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
The extensive use of medicinal herbs to traditionally treat disease persists for generations, and scientific evidence on plant-derived extracts has indicated their numerous biological activities. The Bauhinia, popular known as cow’s paw (“pata de
Externí odkaz:
https://doaj.org/article/63b9566aebf24c1a81d64d182823f2e9
Autor:
THAYSSA S.F. FAGUNDES, ARTHUR L. MACEDO, DHIEGO B. RIGATO, BRUNO S. DO AMARAL, PAULA CHRISTINE JIMENEZ, LETÍCIA V. COSTA-LOTUFO, RENATA F.A. PEREIRA, FÁBIO AGUIAR-ALVES, ANGÉLICA R. SOARES, THATYANA R.A. VASCONCELOS, QUEZIA B. CASS, ALESSANDRA L. VALVERDE
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 93, Iss 4 (2021)
Abstract The extensive marine biodiversity has proved to be a promising source of substances with biomedical potential. In this study, the cytotoxicity of the Brazilian octocoral Phyllogorgia dilatata (Gorgoniidae) was evaluated against two tumor cel
Externí odkaz:
https://doaj.org/article/a9caa9e2f024417e81eb0373cf514ae3
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/ed2bd0cb1e564a2283502f7dce29a007
Autor:
Solida Long, Izadora L. Furlani, Juliana M. de Oliveira, Diana I. S. P. Resende, Artur M. S. Silva, Luís Gales, José A. Pereira, Anake Kijjoa, Quezia B. Cass, Regina V. Oliveira, Emília Sousa, Madalena M. M. Pinto
Publikováno v:
Molecules, Vol 26, Iss 16, p 5070 (2021)
In recent decades, fungi-derived naturally occurring quinazolines have emerged as potential drug candidates. Nevertheless, most studies are conducted for bioactivity assays, and little is known about their absorption, distribution, metabolism, and el
Externí odkaz:
https://doaj.org/article/c02d9b09174f4208890f6eba6f7a3406
Publikováno v:
Molecules, Vol 26, Iss 17, p 5231 (2021)
Metabolomics and lipidomics have demonstrated increasing importance in underlying biochemical mechanisms involved in the pathogenesis of diseases to identify novel drug targets and/or biomarkers for establishing therapeutic approaches for human healt
Externí odkaz:
https://doaj.org/article/6bd3c6592bb24fc1a97f52886c2d612e
Autor:
Bruna R. de Lima, Juliana M. Lima, Jéssica B. Maciel, Carolina Q. Valentim, Rita de Cássia S. Nunomura, Emerson S. Lima, Hector H. F. Koolen, Afonso Duarte L de Souza, Maria Lúcia B. Pinheiro, Quezia B. Cass, Felipe Moura A. da Silva
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Secondary metabolites from natural products are a potential source of acetylcholinesterase inhibitors (AChEIs), which is a key enzyme in the treatment of many neurodegenerative diseases. Inspired by the reported activities of isoquinoline-derivative
Externí odkaz:
https://doaj.org/article/ebb538931c054b639b13494ee5ad1530
Enantiomeric Mixtures in Natural Product Chemistry: Separation and Absolute Configuration Assignment
Publikováno v:
Molecules, Vol 23, Iss 2, p 492 (2018)
Chiral natural product molecules are generally assumed to be biosynthesized in an enantiomerically pure or enriched fashion. Nevertheless, a significant amount of racemates or enantiomerically enriched mixtures has been reported from natural sources.
Externí odkaz:
https://doaj.org/article/cc35f84ca1de469da7cac1b38776295d
Publikováno v:
Química Nova, Vol 33, Iss 10, Pp 2155-2164 (2010)
The development of Chiral Stationary Phases (CSPs) for high performance liquid chromatography has been studied by various researches around the world, especially, since 1980. This simple interest has been transformed into a tool of great technologica
Externí odkaz:
https://doaj.org/article/ce4fc658574d471abda73d158bf342d4
Publikováno v:
Química Nova, Vol 32, Iss 1, Pp 175-187 (2009)
The development and characterization of bioreactors or IMER (immobilized enzyme reactors) as research tools are important in the scope of medicinal chemistry and constitute an alternative for the rational development of drugs. This approach does not
Externí odkaz:
https://doaj.org/article/2ad875d4872a47f89820b7d962b218de
Autor:
Quezia B. Cass, M. Elizabeth Tiritan, Ana Lúcia Bassi, Silvana A. Calafatti, Ana Luiza G. Degani
Publikováno v:
Química Nova, Vol 20, Iss 1, Pp 49-57 (1997)
The importance of chromatographic separation of enantiomers has been acknowledged. This review surveys the development, application and perspectives of polysaccharide carbamates as chiral stationary phase for HPLC.
Externí odkaz:
https://doaj.org/article/9e0f76d84e5144beaa9eb69db9e034a0