Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Quezia, Lacerda"'
Autor:
Rebecca J Melillo, Christiane El Khoury, Amy L Shaver, Moriah Cunningham, Nathalia Benavides, Quezia Lacerda, Felix J Kim, Amy E Leader
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Despite the importance of community involvement in research, little formal training in community outreach and engagement (COE) is offered to cancer research trainees. A collaboration between the Office of COE and the Office of Can
Externí odkaz:
https://doaj.org/article/eb06bea0f0cb4012b31ee2bfd0b9693e
Autor:
Quezia Lacerda, Hebah Falatah, Ji-Bin Liu, Corinne E. Wessner, Brian Oeffinger, Ankit Rochani, Dennis B. Leeper, Flemming Forsberg, Joseph M. Curry, Gagan Kaushal, Scott W. Keith, Patrick O’Kane, Margaret A. Wheatley, John R. Eisenbrey
Publikováno v:
Pharmaceutics, Vol 15, Iss 4, p 1302 (2023)
Tumor hypoxia (oxygen deficiency) is a major contributor to radiotherapy resistance. Ultrasound-sensitive microbubbles containing oxygen have been explored as a mechanism for overcoming tumor hypoxia locally prior to radiotherapy. Previously, our gro
Externí odkaz:
https://doaj.org/article/1a19f6f3948d4cdd96820563b7ebdc10
Publikováno v:
Ultrasound Med Biol
Radiation therapy (RT) causes DNA damage through ionization, leading to double-strand breaks. In addition, it generates reactive oxygen species (ROS), which are toxic to tumor cells and the vasculature. However, hypoxic regions in the tumor have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8803a4598f9383f716fb9b3cb5d3d24
https://doi.org/10.1016/j.ultrasmedbio.2021.01.032
https://doi.org/10.1016/j.ultrasmedbio.2021.01.032
Autor:
Raj Patel, Quezia Lacerda, Brian E. Oeffinger, John R. Eisenbrey, Ankit K. Rochani, Gagan Kaushal, Corinne E. Wessner, Margaret A. Wheatley
Publikováno v:
Polymers; Volume 14; Issue 8; Pages: 1568
Co-delivery of cancer therapeutics improves efficacy and encourages synergy, but delivery faces challenges, including multidrug resistance and spatiotemporal distribution of therapeutics. To address these, we added paclitaxel to previously developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81da77943053feb8eb4ae965f5bea48c
Autor:
Hebah A. Falatah, Quezia Lacerda, Michael Chaga, Corinne E. Wessner, Flemming Forsberg, Dennis B. Leeper, John R. Eisenbrey
Publikováno v:
J Ultrasound Med
The feasibility of activating phase change contrast agents (PCCA) made from Definity (Lantheus Medical Imaging) using X-rays was investigated. A 10 mL of Definity PCCA (0.1 mL PCCA/mL) were injected into gelatin phantoms and irradiated using doses of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e12563410e48a9c6e10bae85cce1c15
https://europepmc.org/articles/PMC9793720/
https://europepmc.org/articles/PMC9793720/
Autor:
Quezia, Lacerda, Ankit, Rochani, Brian, Oeffinger, Ji-Bin, Liu, Corinne E, Wessner, Aylin, Tahmasebi, Hebah, Falatah, Philip, Lee, Dennis B, Leeper, Flemming, Forsberg, Joseph, Curry, Scott W, Keith, Patrick, O'Kane, Gagan, Kaushal, Margaret A, Wheatley, John R, Eisenbrey
Publikováno v:
Int J Pharm
Prior work has shown that microbubble-assisted delivery of oxygen improves tumor oxygenation and radiosensitivity, albeit over a limited duration. Lonidamine (LND) has been investigated because of its ability to stimulate glycolysis, lactate producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730898a6298a784001eb928cfc3d65e0
https://doi.org/10.1016/j.ijpharm.2022.122072
https://doi.org/10.1016/j.ijpharm.2022.122072
Autor:
Patrick O'Kane, Flemming Forsberg, Gagan Kaushal, Margaret A. Wheatley, John R. Eisenbrey, Raj Patel, Brian E. Oeffinger, Quezia Lacerda, Ankit K. Rochani, Dennis B. Leeper
Publikováno v:
2020 IEEE International Ultrasonics Symposium (IUS).
Lonidamine (LND) has been widely explored due to its ability to target metabolic glycolysis and mitochondrial respiration in tumors [4]. However, clinical translation has stalled due to poor bioavailability after oral administration. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::978e8790b6278c362bf09bf6ecaab921
https://doi.org/10.1109/ius46767.2020.9251788
https://doi.org/10.1109/ius46767.2020.9251788
Autor:
Margaret A. Wheatley, Jacob Powell, Quezia Lacerda, Purva B. Vaidya, Raj Patel, John R. Eisenbrey, Brian E. Oeffinger
Publikováno v:
Colloids Surf B Biointerfaces
We have developed oxygen filled microbubbles, SE61O2, for localized, ultrasound-triggered oxygen delivery to hypoxic tumors prior to radiation therapy. Microbubbles, created by sonication, have a shell composed of D-α-Tocopherol polyethylene glycol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfe9a2144a267b83e28262ac89dd6b7
https://doi.org/10.1016/j.colsurfb.2021.112049
https://doi.org/10.1016/j.colsurfb.2021.112049