Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Quetzalcoatl Escalante-Covarrubias"'
Autor:
Quetzalcoatl Escalante-Covarrubias, Lucía Mendoza-Viveros, Mirna González-Suárez, Román Sitten-Olea, Laura A. Velázquez-Villegas, Fernando Becerril-Pérez, Ignacio Pacheco-Bernal, Erick Carreño-Vázquez, Paola Mass-Sánchez, Marcia Bustamante-Zepeda, Ricardo Orozco-Solís, Lorena Aguilar-Arnal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-24 (2023)
The timing of NAD + supply determines its efficacy to treat metabolic disease. Here, the authors show that increasing NAD + at the early active phase maximizes weight loss and glucose regulation in mice. NAD + can displace the phase of the liver cloc
Externí odkaz:
https://doaj.org/article/fbdcecb98964451ea63d43a530a1552e
Autor:
Abdalla Ahmed, Jibran Nehal Syed, Lijun Chi, Yaxu Wang, Carmina Perez-Romero, Dorothy Lee, Etri Kocaqi, Amalia Caballero, Jielin Yang, Quetzalcoatl Escalante-Covarrubias, Akihiko Ishimura, Takeshi Suzuki, Lorena Aguilar-Arnal, Gerard Bryan Gonzales, Kyoung-Han Kim, Paul Delgado-Olguín
Publikováno v:
Nature Cardiovascular Research. 2:174-191
Cardiac metabolism is deranged in heart failure, but underlying mechanisms remain unclear. Here, we show that lysine demethylase 8 (Kdm8) maintains an active mitochondrial gene network by repressing Tbx15, thus preventing dilated cardiomyopathy leadi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f66ac2245a8b32c41111ad8108cc255
https://doi.org/10.1038/s44161-023-00214-0
https://doi.org/10.1038/s44161-023-00214-0
Publikováno v:
Current Opinion in Toxicology. 8:93-101
The circadian clock, a highly complex network of hierarchical oscillators, integrates daily environmental signaling to organize temporal segregation of metabolic pathways in a tissue-specific manner. Hence, 24-h period oscillations are observed in ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b2b5ff399b01bae3d419ed4fa3b63c2
https://doi.org/10.1016/j.cotox.2018.03.003
https://doi.org/10.1016/j.cotox.2018.03.003