Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Questa, Hope"'
Autor:
Lynne T. O'Brien, Michelle Guy, David P. Dearnaley, R A Wilkinson, Z Kote-Jarai, Sameer Jhavar, Julia C. Meitz, Cyril Fisher, Doug Easton, D G R Evans, A. R. Norman, Alison Falconer, Matthew S. Forrest, Yolanda Barbachano, Elizabeth Page, Amanda L. Hall, Peter Osin, Sarah Bullock, S M Edwards, Questa Hope, Rosalind A. Eeles, Audrey Ardern-Jones, Beatrice N. Gehr-Swain
Publikováno v:
British Journal of Cancer
Prostate cancer (PrCa) is a significant public health problem. In the European Union, approximately 200 000 men are diagnosed annually with the disease. There are 35 515 cases (Cancer Research UK, 2009a) per year in the United Kingdom and 10 239 deat
Autor:
Alison J. Sinclair, Salama Al Mehairi, Questa Hope, Derek N. Woolfson, Celine Schelcher, Michelle J. West, Kirsty Flower, Elizabeth Verrall, Beth Bromley
Publikováno v:
Journal of Virology. 81:7149-7155
The Epstein-Barr virus transcription factor Zta (encoded by BZLF1 ) is a bZIP protein containing an α-helical coiled-coil homodimerization motif (zipper). The Zta zipper forms less-stable dimers than other bZIP proteins, and an adjacent region (CT)
Autor:
Daniel J, Schaid, Shannon K, McDonnell, Katherine E, Zarfas, Julie M, Cunningham, Scott, Hebbring, Stephen N, Thibodeau, Rosalind A, Eeles, Douglas F, Easton, William D, Foulkes, Jacques, Simard, Graham G, Giles, John L, Hopper, Lovise, Mahle, Pal, Moller, Michael, Badzioch, D Timothy, Bishop, Chris, Evans, Steve, Edwards, Julia, Meitz, Sarah, Bullock, Questa, Hope, Michelle, Guy, Chih-lin, Hsieh, Jerry, Halpern, Raymond R, Balise, Ingrid, Oakley-Girvan, Alice S, Whittemore, Jianfeng, Xu, Latchezar, Dimitrov, Bao-Li, Chang, Tamara S, Adams, Aubrey R, Turner, Deborah A, Meyers, Danielle M, Friedrichsen, Kerry, Deutsch, Suzanne, Kolb, Marta, Janer, Leroy, Hood, Elaine A, Ostrander, Janet L, Stanford, Charles M, Ewing, Marta, Gielzak, Sarah D, Isaacs, Patrick C, Walsh, Kathleen E, Wiley, William B, Isaacs, Ethan M, Lange, Lindsey A, Ho, Jennifer L, Beebe-Dimmer, David P, Wood, Kathleen A, Cooney, Daniela, Seminara, Tarja, Ikonen, Agnes, Baffoe-Bonnie, Henna, Fredriksson, Mika P, Matikainen, Teuvo L J, Tammela, Joan, Bailey-Wilson, Johanna, Schleutker, Christiane, Maier, Kathleen, Herkommer, Josef J, Hoegel, Walther, Vogel, Thomas, Paiss, Fredrik, Wiklund, Monica, Emanuelsson, Elisabeth, Stenman, Björn-Anders, Jonsson, Henrik, Grönberg, Nicola J, Camp, James, Farnham, Lisa A, Cannon-Albright, William J, Catalona, Brian K, Suarez, Kimberly A, Roehl
Publikováno v:
Human Genetics. 120:471-485
While it is widely appreciated that prostate cancers vary substantially in their propensity to progress to a life-threatening stage, the molecular events responsible for this progression have not been identified. Understanding these molecular mechani
Autor:
Douglas F. Easton, Kenneth Muir, Gianluca Severi, Sarah Bullock, Ketil Heimdal, Richard S. Houlston, William D. Foulkes, Questa Hope, David P. Dearnaley, Lovise Maehle, Stephen M. Edwards, Sameer Jhavar, David Roquis, James C. Engert, Christine Southgate, Daniel Sinnett, Nancy Hamel, Michael D. Badzioch, Jacques Simard, Melissa C. Southey, Alison Falconer, A Dowe, Graham G. Giles, John L. Hopper, Christopher H. Evans, Pål Møller, Rosalind A. Eeles, Dallas R. English, Julia C. Meitz
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 14:397-402
Background: Variants in the gene encoding the macrophage scavenger receptor 1 (MSR14) protein have been identified in men with prostate cancer, and several small studies have suggested that the 999C>T (R293X) protein-truncating mutation may be associ
Autor:
Karlsson, Questa Hope
Epstein Barr Virus (EBV) is a γ-herpesvirus infecting around 95% of the human\ud population. EBV infection is life-long and asymptomatic in the majority of individuals,\ud however EBV is associated with Nasopharyngeal Carcinoma, Burkitt's\ud lymphom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::e716697094097eb515261815c145bcca
http://sro.sussex.ac.uk/id/eprint/47212/1/Karlsson,_Questa_Hope.pdf
http://sro.sussex.ac.uk/id/eprint/47212/1/Karlsson,_Questa_Hope.pdf
Autor:
Joan E. Bailey-Wilson, Gail P. Jarvik, Douglas F. Easton, Sarah D. Isaacs, Caroline E. Mohai, William B. Isaacs, Björn Anders Jonsson, Alice S. Whittemore, Shannon K. McDonnell, Mika P. Matikainen, Janet L. Stanford, Kathleen A. Cooney, Kerry Deutsch, Teuvo L.J. Tammela, Rosalind A. Eeles, Tamara S. Adams, Jianfeng Xu, Steve Edwards, Suzanne Kolb, Danielle M. Friedrichsen, Stephen N. Thibodeau, Fredrik Wiklund, Questa Hope, Deborah A. Meyers, Agnes Baffoe-Bonnie, Michael D. Badzioch, Jacques Simard, Leroy Hood, Raymond N. Balise, Kathleen Herkommer, Pål Møller, Christopher P. Evans, Jennifer L. Beebe-Dimmer, Nicola J. Camp, Jerry Halpern, Scott J. Hebbring, Marta Gielzak, Ethan M. Lange, Patrick C. Walsh, Daniela Seminara, Charles M. Ewing, Elaine A. Ostrander, John L. Hopper, Monica Emanuelsson, Daniel J. Schaid, Josef Hoegel, Graham G. Giles, Chih Iin Hsieh, Katherine E. Zarfas, Kathleen E. Wiley, Latchezar Dimitrov, Elisabeth Stenman, Julie M. Cunningham, Bao Li Chang, William D. Foulkes, Henna Fredriksson, Walther Vogel, Ingrid Oakley-Girvan, James M. Farnham, Marta Janer, Tarja Ikonen, Lovise Mahle, Aubrey R. Turner, Sarah Bullock, Christiane Maier, Thomas Paiss, Johanna Schleutker, Lisa A. Cannon-Albright, Henrik Grönberg, Julia C. Meitz, Tim Bishop
Publikováno v:
The American Journal of Human Genetics. (2):219-229
Evidence of the existence of major prostate cancer (PC)-susceptibility genes has been provided by multiple segregation analyses. Although genomewide screens have been performed in over a dozen independent studies, few chromosomal regions have been co
Autor:
David P. Dearnaley, Audrey Ardern-Jones, A Murkin, J. Kelly, Zsofia Kote-Jarai, Peter Osin, Julia C. Meitz, Doug Easton, Christine Southgate, Rashmi Singh, A Dowe, Sue Williams, Margaret Stevens, Rosalind A. Eeles, Stephen M. Edwards, Rachel Jackson, Dawn Teare, Rifat Hamoudi, Richard A. Oram, Alison Falconer, A.J. Bruce Ponder, Simon A. Gayther, Questa Hope
Publikováno v:
The American Journal of Human Genetics. (1):1-12
Studies of families with breast cancer have indicated that male carriers of BRCA2 mutations are at increased risk of prostate cancer, particularly at an early age. To evaluate the contribution of BRCA2 mutations to early-onset prostate cancer, we scr